نتائج البحث - "David J. Brooks"

1

Mapping Cholinergic Synaptic Loss in Parkinson’s Disease: An [18F]FEOBV PET Case-Control Study

المؤلفون: Jacob Horsager, Niels Okkels, Allan K. Hansen, Malene F. Damholdt, Katrine H. Andersen, Tatyana D. Fedorova, Ole Lajord Munk, Erik H. Danielsen, Nicola Pavese, David J. Brooks, Per Borghammer

المصدر: Horsager, J, Okkels, N, Hansen, A K, Damholdt, M F, Andersen, K H, Fedorova, T D, Munk, O L, Danielsen, E H, Pavese, N, Brooks, D J & Borghammer, P 2022, ' Mapping Cholinergic Synaptic Loss in Parkinson's Disease : An [18F]FEOBV PET Case-Control Study ', Journal of Parkinson's Disease, vol. 12, no. 8, pp. 2493-2506 . https://doi.org/10.3233/JPD-223489Test

مصطلحات موضوعية: Cellular and Molecular Neuroscience, positron emission tomography, vesicular acetylcholine transporter, Case-Control Studies, Positron-Emission Tomography, Parkinson’s disease, [18F]FEOBV, Cholinergic Agents, Disease Progression, Humans, Parkinson Disease, Neurology (clinical), Cholinergic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754f8a7539bb7452ec182e565da60e8bTest
https://doi.org/10.3233/jpd-223489Test

2

Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease

المساهمون: National Institute for Health Research, UK DRI Ltd

المصدر: Venkataraman, A V, Mansur, A, Rizzo, G, Bishop, C, Lewis, Y, Kocagoncu, E, Lingford-Hughes, A, Huiban, M, Passchier, J, Rowe, J B, Tsukada, H, Brooks, D J, Martarello, L, Comley, R A, Chen, L, Schwarz, A J, Hargreaves, R, Gunn, R N, Rabiner, E A & Matthews, P M 2022, ' Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease ', Science Translational Medicine, vol. 14, no. 658, eabk1051 . https://doi.org/10.1126/scitranslmed.abk1051Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f1dff4aaab7fcdad74b5dfc66d7a81Test
https://doi.org/10.1126/scitranslmed.abk1051Test

3

Healthy brain aging assessed with [

المؤلفون: Katrine B, Andersen, Allan K, Hansen, Karoline, Knudsen, Anna Christina, Schacht, Malene F, Damholdt, David J, Brooks, Per, Borghammer

المصدر: Nuclear medicine and biology.

مصطلحات موضوعية: Healthy Aging, Glucose, Fluorodeoxyglucose F18, Positron-Emission Tomography, Brain, Humans, Aged, Glycoproteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::e6f732fc3dfa3864adc944d2d9ce17b5Test
https://pubmed.ncbi.nlm.nih.gov/35820300Test

4

Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder

المؤلفون: Kristina Bacher Svendsen, Alex Iranzo, Nicola Pavese, Dolores Vilas, David J. Brooks, Eduardo Tolosa, Alicia Garrido, Morten Gersel Stokholm, Marit Otto, Arne Møller, Kristian Stær, Mónica Serradell, Per Borghammer, Joan Santamaria, Karen Østergaard, Carles Gaig

المصدر: Stær, K, Iranzo, A, Stokholm, M G, Østergaard, K, Serradell, M, Otto, M, Svendsen, K B, Garrido, A, Vilas, D, Santamaria, J, Møller, A, Gaig, C, Brooks, D J, Borghammer, P, Tolosa, E & Pavese, N 2020, ' Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder ', Parkinsonism & Related Disorders, vol. 81, pp. 89-93 . https://doi.org/10.1016Test/j.parkreldis.2020.10.014

مصطلحات موضوعية: Male, 0301 basic medicine, Parkinson's disease, Substantia nigra, REM Sleep Behavior Disorder, REM sleep behavior disorder, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Substantia Innominata, medicine, Humans, Cognitive Dysfunction, Donepezil, Carbon Radioisotopes, Neuroinflammation, Aged, Cerebral Cortex, Inflammation, business.industry, Substantia innominata, Middle Aged, Isoquinolines, Mental Status and Dementia Tests, medicine.disease, Acetylcholinesterase, Cortex (botany), 030104 developmental biology, Neurology, chemistry, Positron-Emission Tomography, Cholinergic, Female, Cholinesterase Inhibitors, Microglia, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a4ee8ab93f9a2856d261984fb1f930Test
https://doi.org/10.1016Test/j.parkreldis.2020.10.014

5

In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET

المؤلفون: David J. Brooks, Anne M. Landau, Majken B. Thomsen, Anna C. Schacht, Thea P. Lillethorup, Jan Jacobsen, Mette Kildevæld Simonsen, Marina Romero-Ramos

المصدر: Thomsen, M, Jacobsen, J, Lillethorup, T P, Schacht, A C, Simonsen, M I T, Romero-Ramos, M, Brooks, D J & Landau, A 2021, ' In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET ', Journal of Cerebral Blood Flow and Metabolism, vol. 41, no. 4, pp. 819-830 . https://doi.org/10.1177/0271678X20931140Test
J Cereb Blood Flow Metab

مصطلحات موضوعية: Levetiracetam, Nerve Tissue Proteins, Pharmacology, Synaptic vesicle, Neuroprotection, Rats, Sprague-Dawley, Synapse, Lesion, Hydroxydopamines, 03 medical and health sciences, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, synapse, In vivo, medicine, Animals, rat, Parkinson Disease, Secondary, 030304 developmental biology, SV2A, 0303 health sciences, Membrane Glycoproteins, Chemistry, Neurodegeneration, neurodegeneration, Original Articles, Quinolinic Acid, medicine.disease, Corpus Striatum, Rats, SV2A protein, Kinetics, Huntington Disease, Neuroprotective Agents, [11C]UCB-J PET, Neurology, Positron-Emission Tomography, Synapses, embryonic structures, Autoradiography, Anticonvulsants, Female, Neurology (clinical), Radiopharmaceuticals, medicine.symptom, Cardiology and Cardiovascular Medicine, 030217 neurology & neurosurgery, Quinolinic acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d936e22954b72b8ef486a681c907b897Test
https://doi.org/10.1177/0271678x20931140Test

6

Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder

المؤلفون: Joan Santamaria, Tatyana D. Fedorova, Kotaro Hiraoka, Alicia Garrido, Marit Otto, Nobuyuki Okamura, Anette Torvin Møller, Alex Iranzo, Carles Gaig, Dolores Vilas, M. Gersel Stokholm, Eduard Tolosa, Karen Østergaard, David J. Brooks, Nicola Pavese, Per Borghammer, Mónica Serradell, K. Bacher Svendsen

المصدر: Gersel Stokholm, M, Iranzo, A, Østergaard, K, Serradell, M, Otto, M, Bacher Svendsen, K, Garrido, A, Vilas, D, Fedorova, T D, Santamaria, J, Møller, A, Gaig, C, Hiraoka, K, Brooks, D J, Okamura, N, Borghammer, P, Tolosa, E & Pavese, N 2020, ' Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder ', European Journal of Neurology, vol. 27, no. 4, pp. 644-652 . https://doi.org/10.1111/ene.14127Test

مصطلحات موضوعية: DOPAMINERGIC DEFICITS, Male, Cingulate cortex, positron emission tomography, Parkinson's disease, Polysomnography, REM Sleep Behavior Disorder, Lewy body disease, DIAGNOSIS, 03 medical and health sciences, 0302 clinical medicine, PARKINSONS-DISEASE, mental disorders, MANAGEMENT, medicine, Cholinesterases, Humans, Dementia, 030212 general & internal medicine, rapid eye movement sleep behaviour disorder, Aged, Temporal cortex, Dementia with Lewy bodies, business.industry, DEMENTIA, Parkinsonism, NEURODEGENERATION, Brain, Montreal Cognitive Assessment, ACETYLTRANSFERASE ACTIVITY, Middle Aged, COGNITIVE IMPAIRMENT, medicine.disease, LEWY BODIES, Denervation, acetylcholine, Dihydroxyphenylalanine, ALZHEIMERS-DISEASE, Dorsolateral prefrontal cortex, medicine.anatomical_structure, Neurology, Positron-Emission Tomography, Female, Neurology (clinical), business, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6bb785d695e7d8b6bc98668eed9bcbTest
http://hdl.handle.net/10097/00130915Test

7

A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies

المساهمون: Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging, ACS - Heart failure & arrhythmias, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Chalon, Sylvie, VU University Medical Center [Amsterdam], Univ Groningen, Univ Med Ctr Groningen, Lund University [Lund], Perani, D, Iaccarino, L, Lammertsma, Aa, Windhorst, Ad, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A, on behalf of all partners of the IMBI, Project, Lammertsma, A, Windhorst, A, Bottlaender, M, Brooks, D, Carroll, M, Chalon, S, Gee, A, Gerhard, A, Halldin, C, Herholz, K, Herth, M, Hinz, R, Knudsen, G, Kuhnast, B, Lopez-Picon, F, Moresco, R, Pappata, S, Rinne, J, Rodriguez-Vieitez, E, Santiago-Ribeiro, M, Turkheimer, F, Van Laere, K, Varrone, A, Vercouillie, J, Winkeler, A

المصدر: Perani, D, Iaccarino, L, Lammertsma, A A, Windhorst, A D, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A H & IMBI Project 2019, ' A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies ', Alzheimer's and Dementia, vol. 15, no. 8, pp. 1081-1103 . https://doi.org/10.1016Test/j.jalz.2019.02.004
Alzheimer's and Dementia, 15(8), 1081-1103. Elsevier
Perani, D, Iaccarino, L, Lammertsma, A A, Windhorst, A D, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A H & Partners IMBI Project 2019, ' A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies ', Alzheimer's & Dementia, vol. 15, no. 8, pp. 1081-1103 . https://doi.org/10.1016Test/j.jalz.2019.02.004
Alzheimers & dementia, 15(8), 1081-1103. ELSEVIER SCIENCE INC
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2019, 15 (8), pp.1081-1103. ⟨10.1016/j.jalz.2019.02.004⟩

مصطلحات موضوعية: 0301 basic medicine, 18-KDA TRANSLOCATOR PROTEIN, MILD COGNITIVE IMPAIRMENT, Epidemiology, PET TRACER F-18-AV-1451, [SDV]Life Sciences [q-bio], Diagnostic tools, Abnormal protein, AMYOTROPHIC-LATERAL-SCLEROSIS, chemistry.chemical_compound, 0302 clinical medicine, Neuroinflammation, Medicine, TAU-PET, ComputingMilieux_MISCELLANEOUS, IN-VIVO, medicine.diagnostic_test, Health Policy, Amyloid, Neuroinflammation, PET molecular imaging, Protheinopathies, Radiotracers, Tau, Neurodegenerative Diseases, Frontotemporal lobar degeneration, ALZHEIMERS ASSOCIATION WORKGROUPS, 3. Good health, [SDV] Life Sciences [q-bio], Psychiatry and Mental health, Radiotracers, Positron emission tomography, Protheinopathie, Specific protein, Amyloid, PET molecular imaging, Neuroimaging, Neuropathology, CEREBRAL AMYLOID ANGIOPATHY, 03 medical and health sciences, Cellular and Molecular Neuroscience, Developmental Neuroscience, Humans, Proteostasis Deficiencies, FRONTOTEMPORAL LOBAR DEGENERATION, Radiotracer, business.industry, PITTSBURGH COMPOUND-B, medicine.disease, 030104 developmental biology, chemistry, Positron-Emission Tomography, Protheinopathies, Neurology (clinical), Geriatrics and Gerontology, Molecular imaging, Tau, business, Pittsburgh compound B, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5303c97f26d0a4c4daf3ecbe61eb94fTest
https://research.rug.nl/en/publications/31d7324a-6cc7-43e1-8d81-b70469a0330aTest

8

Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [

المؤلفون: Ali K, Vibholm, Martin J, Dietz, Sándor, Beniczky, Jakob, Christensen, Andreas, Højlund, Jan, Jacobsen, Dirk, Bender, Arne, Møller, David J, Brooks

المصدر: EpilepsiaREFERENCES. 62(12)

مصطلحات موضوعية: Drug Resistant Epilepsy, Epilepsy, Fluorodeoxyglucose F18, Positron-Emission Tomography, Brain, Humans, Electroencephalography, Epilepsies, Partial, Magnetic Resonance Imaging, Receptors, N-Methyl-D-Aspartate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::dc00a6082e788738f20ee60f5e422a27Test
https://pubmed.ncbi.nlm.nih.gov/34558066Test

9

Reduced Synaptic Density in Patients with Lewy Body Dementia: An [

المؤلفون: Katrine B, Andersen, Allan K, Hansen, Malene F, Damholdt, Jacob, Horsager, Casper, Skjaerbaek, Hanne, Gottrup, Henriette, Klit, Anna Christina, Schacht, Erik H, Danielsen, David J, Brooks, Per, Borghammer

المصدر: Movement disorders : official journal of the Movement Disorder SocietyReferences. 36(9)

مصطلحات موضوعية: Lewy Body Disease, Alzheimer Disease, Positron-Emission Tomography, Humans, Cognitive Dysfunction, Parkinson Disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::25458f4040f0dd79985f2dd5b7b29fbbTest
https://pubmed.ncbi.nlm.nih.gov/33899255Test

10

Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder

المؤلفون: Karen Østergaard, Carles Gaig, David J. Brooks, Kristine Farmen, Eduardo Tolosa, Mónica Serradell, Per Borghammer, Kristina Bacher Svendsen, Alicia Garrido, Morten Gersel Stokholm, Marit Otto, Alex Iranzo, Sara K. Nissen, Arne Møller, Nicola Pavese, Joan Santamaria, Dolores Vilas, Marina Romero-Ramos

المصدر: Farmen, K, Nissen, S K, Stokholm, M G, Iranzo, A, Østergaard, K, Serradell, M, Otto, M, Svendsen, K B, Garrido, A, Vilas, D, Borghammer, P, Santamaria, J, Møller, A, Gaig, C, Brooks, D J, Tolosa, E, Pavese, N & Romero-Ramos, M 2021, ' Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 10, e2020858118 . https://doi.org/10.1073/pnas.2020858118Test
Proc Natl Acad Sci U S A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2becded01064f4f976e0f987f5c183a5Test
https://doi.org/10.1073/pnas.2020858118Test

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