دورية أكاديمية

Referral patterns and social deprivation in paracetamol-induced liver injury in Scotland.

التفاصيل البيبلوغرافية
العنوان: Referral patterns and social deprivation in paracetamol-induced liver injury in Scotland.
المؤلفون: Newsome, Philip N, Bathgate, Andrew J, Henderson, Neil C, MacGilchrist, Alastair J, Plevris, John N, Masterton, George, Garden, O James, Lee, Alistair, Hayes, Peter C, Simpson, Kenneth J
المصدر: Lancet. 11/10/2001, Vol. 358 Issue 9293, p1612. 2p.
مصطلحات موضوعية: *ACETAMINOPHEN, *LIVER failure, *POOR people, *DRUG laws
مصطلحات جغرافية: UNITED Kingdom
مستخلص: Paracetamol overdose is the commonest cause of acute liver failure in the UK, which has led to measures to restrict its sale. We aimed to establish whether changes in the referral of patients with paracetamol-induced acute liver failure have occurred since the introduction of legislation. We compared data from patients admitted to the Scottish Liver Transplantation Unit in 1992-98 with those admitted in 1998-2001. The incidence of paracetamol-induced liver failure, severity of patients' illness, and outcome did not differ between the groups. Patients with paracetamol-induced acute liver failure had higher Carstairs scores (1.99 [95% CI 1.33-2.65]; n5190) than patients with non-paracetamol acute liver failure (0.02 [20.79 to 0.84]; n568). We have shown an association between paracetamol-induced acute liver failure and social deprivation. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:01406736
DOI:10.1016/S0140-6736(01)06663-6