المؤلفون: Karel F. Liem, Emilie Legué, Ming Ma, Stefan Somlo, Xin Tian

المصدر: J Am Soc Nephrol

مصطلحات موضوعية: 0301 basic medicine, Cell signaling, TRPP Cation Channels, Autosomal dominant polycystic kidney disease, Biology, urologic and male genital diseases, Kidney cysts, Zinc Finger Protein GLI1, 03 medical and health sciences, Mice, 0302 clinical medicine, Polycystic kidney disease, medicine, Animals, Hedgehog Proteins, Hedgehog, PKD1, urogenital system, Cilium, General Medicine, medicine.disease, Polycystic Kidney, Autosomal Dominant, Hedgehog signaling pathway, female genital diseases and pregnancy complications, Cell biology, Disease Models, Animal, 030104 developmental biology, Basic Research, Nephrology, embryonic structures, medicine.symptom, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c8e906bec0b16179da875276644e54Test
https://pubmed.ncbi.nlm.nih.gov/31451534Test

المؤلفون: Emilie Legué, Karel F. Liem

المصدر: Current Biology. 29:803-812.e5

مصطلحات موضوعية: Male, 0301 basic medicine, Autosomal dominant polycystic kidney disease, Biology, urologic and male genital diseases, Kidney cysts, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Ciliogenesis, medicine, Polycystic kidney disease, Animals, Mice, Knockout, Polycystic Kidney Diseases, PKD1, urogenital system, Cilium, Intracellular Signaling Peptides and Proteins, medicine.disease, Cell biology, Protein Transport, Ciliopathy, 030104 developmental biology, Female, medicine.symptom, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Genetic screen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaaaf97d42ab321f28d7032a8f90bd2Test
https://doi.org/10.1016/j.cub.2019.01.054Test

المؤلفون: Moshe Yaniv, Marco Pontoglio, Antonia Doyen, Jean-François Nicolas, Vicente E. Torres, Emilie Legué, Evelyne Fischer, Faridabano Nato

المساهمون: Expression Génétique et Maladies (EGM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie Moléculaire du Développement, Production de Protéines Recombinantes et d'Anticorps (Plate-Forme), Institut Pasteur [Paris] (IP), Mayo Clinic [Rochester], This work was supported by the PKD Foundation, Genzyme Corporation and La Ligue contre le Cancer, as well as by grants (to E.L. and J.F.N.) from Cells into Organs (EU Framework 6 project LSHM-CT2003-504468), EurostemCell (EU Framework 6 project LHSB-CT2003-503005) and the Association Française contre les Myopathies (AFM)., We are grateful to B. Mateescu for the H3pS10 antibody and to A. Blanchard for the aqp2 antibody. We thank E. Perret, P. Roux and M. Delarue for assistance and advice, and F. Terzi and J. Weitzman for helpful discussions and for critical reading of the manuscript. E.F. is a fellow of the Association pour l'Information et la Recherche sur les maladies Rénales Génétiques (AIRG)., Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Institut Pasteur [Paris]

المصدر: Nature Genetics
Nature Genetics, 2006, 38 (1), pp.21-23. ⟨10.1038/ng1701⟩
Nature Genetics, Nature Publishing Group, 2006, 38 (1), pp.21-23. ⟨10.1038/ng1701⟩

مصطلحات موضوعية: medicine.medical_specialty, Cell division, [SDV]Life Sciences [q-bio], Fibrocystin, Morphogenesis, Mitosis, Spindle Apparatus, Biology, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Mucoproteins, 0302 clinical medicine, Internal medicine, Uromodulin, Cell polarity, Genetics, medicine, Polycystic kidney disease, Animals, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Hepatocyte Nuclear Factor 1-beta, 030304 developmental biology, Polycystic Kidney Diseases, 0303 health sciences, Cell Polarity, medicine.disease, Mice, Mutant Strains, Rats, Cell biology, Disease Models, Animal, Tamoxifen, Kidney Tubules, Tubule, Endocrinology, biology.protein, 030217 neurology & neurosurgery, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a888a855239447c909fac70d7b8e557Test
https://doi.org/10.1038/ng1701Test