دورية أكاديمية
Platelet-derived growth factors from a single donor by apheresis and one freeze–thaw cycle for treating medication-related osteonecrosis of the jaw
| العنوان: | Platelet-derived growth factors from a single donor by apheresis and one freeze–thaw cycle for treating medication-related osteonecrosis of the jaw |
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| المؤلفون: | Vidán Estévez, Julia María, Escalante Barrigón, Fernando, Sánchez Herráez, Sergio, Seco Calvo, Jesús Ángel |
| المساهمون: | Fisioterapia, Facultad de Ciencias de la Salud |
| بيانات النشر: | Future Medicine |
| سنة النشر: | 2022 |
| المجموعة: | Universidad de León: BULERIA |
| مصطلحات موضوعية: | Fisioterapia, Al-PRP, Medication-related, Osteonecrosis of the jaw, MRONJ, Multiple myeloma, PDGF, Platelet-derived growth factor |
| الوصف: | [EN] To assess whether the use of allogeneic platelet-derived growth factors could serve as a feasible, effective and safe biological therapy for the treatment of medication-related osteonecrosis of the jaw (MRONJ). Materials & methods: Patients with multiple myeloma and MRONJ were included and treated with allogeneic platelet-rich plasma, continued for between 6 and 18 weeks (mean: 9). Results: We observed a treatment success rate of 87.5% (p < 0.05). Assessing the association between healing and treatment duration, we observed a statistically significant relationship (χ2 = 8.00; p = 0.018; Cramer’s V = 1), confirming that healing was very closely related to the duration of the treatment. Conclusion: Allogeneic platelet-rich plasma could be a recommended treatment for MRONJ. Future research with a large sample to validate our findings is required. ; SI |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1746-0751 1746-076X |
| العلاقة: | Julia Vidán-Estévez, Fernando Escalante-Barrigón, Sergio Sánchez-Herráez & Jesús Seco-Calvo (2022) Platelet-derived growth factors from a single donor by apheresis and one freeze-thaw cycle for treating medication-related osteonecrosis of the jaw. Regenerative medicine 17 (12) https://doi.org/10.2217/rme-2022-0126Test; https://hdl.handle.net/10612/19452Test |
| DOI: | 10.2217/rme-2022-0126 |
| DOI: | 10.2217/RME-2022-0126 |
| الإتاحة: | https://doi.org/10.2217/RME-2022-0126Test https://hdl.handle.net/10612/19452Test |
| حقوق: | Attribution-NonCommercial-NoDerivatives 4.0 Internacional ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.13C17824 |
| قاعدة البيانات: | BASE |
| تدمد: | 17460751 1746076X |
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| DOI: | 10.2217/rme-2022-0126 |