نتائج البحث - "Parasite Physiology"

1

Biosynthesis of heme O in intraerythrocytic stages of Plasmodium falciparum and potential inhibitors of this pathway

المؤلفون: Gerhard Wunderlich, Brenda Analía Cirulli, Fernando G. de Almeida, Gerardo Cebrián-Torrejón, Antonio Doménech-Carbó, Raquel M. Simão-Gurge, Alejandro M. Katzin, Eliana Fernanda Galindo Cubillos, Julia A. Cricco

المصدر: RepHipUNR (UNR)
Universidad Nacional de Rosario
instacron:UNR
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b84dae09b2ab9ddac016977128c9b56Test

2

The natural function of the malaria parasite's chloroquine resistance transporter

المؤلفون: Nicole S. Lancaster, Manuel Llinás, Sarah H. Shafik, Robert L. Summers, Simon J. Hogg, Malcolm J. McConville, Kawthar Barkat, Rowena E. Martin, Simon A. Cobbold, Sashika N. Richards

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: 0301 basic medicine, Drug Resistance, Protozoan Proteins, General Physics and Astronomy, 02 engineering and technology, Vacuole, Drug resistance, Xenopus laevis, Chloroquine, Parasite physiology, Malaria, Falciparum, lcsh:Science, Multidisciplinary, biology, Membrane transport protein, 021001 nanoscience & nanotechnology, Parasite biology, Protein Transport, Female, 0210 nano-technology, Oligopeptides, geographic locations, medicine.drug, Science, Plasmodium falciparum, Biological Transport, Active, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, Microbiology, Host-Parasite Interactions, 03 medical and health sciences, Antimalarials, parasitic diseases, medicine, Animals, Humans, Metabolomics, fungi, Membrane Transport Proteins, Transporter, General Chemistry, biology.organism_classification, Multiple drug resistance, 030104 developmental biology, Peptide transport, biology.protein, Oocytes, lcsh:Q, Mutant Proteins, Lysosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c80cce56587a46440b3acf33d9e412Test
https://pubmed.ncbi.nlm.nih.gov/32764664Test

3

Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum

المؤلفون: Rahul Navale, Aparna Devi Allanki, Atul, Puran Singh Sijwali

المصدر: PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e113220 (2014)

مصطلحات موضوعية: Erythrocytes, Protozoan Proteins, lcsh:Medicine, Vacuole, Biochemistry, chemistry.chemical_compound, Pepstatins, Molecular Cell Biology, lcsh:Science, Protein Metabolism, Cellular Stress Responses, Multidisciplinary, Microfilament Proteins, Chloroquine, Cell biology, Cell Processes, Medical Microbiology, Doxycycline, Research Article, Programmed cell death, Saccharomyces cerevisiae Proteins, ATG8, Molecular Sequence Data, Plasmodium falciparum, Saccharomyces cerevisiae, Biology, Apicoplasts, Microbiology, Antimalarials, Leucine, Food vacuole, Autophagy, Humans, Protease Inhibitors, Amino Acid Sequence, Microbial Pathogens, Apicoplast, Life Cycle Stages, Sequence Homology, Amino Acid, Adenine, lcsh:R, Parasite Physiology, Biology and Life Sciences, Autophagy-Related Protein 8 Family, Cell Biology, biology.organism_classification, Metabolism, chemistry, Gene Expression Regulation, lcsh:Q, Parasitology, Genome, Protozoan, Sequence Alignment, Pepstatin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95400caa2a3d4a1f88e38faa641b42c2Test
https://pubmed.ncbi.nlm.nih.gov/25426852Test

4

Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism

المؤلفون: Rainer Breitling, Gavin Blackburn, Graham H. Coombs, Janet Storm, Sylke Müller, Achuthanunni Chokkathukalam, David G. Watson, Sonal Sethia

المصدر: PLoS Pathogens, Vol 10, Iss 1, p e1003876 (2014)
PLoS Pathogens; Vol 10
PLoS Pathogens

مصطلحات موضوعية: Erythrocytes, Protozoan Proteins, Pathogenesis, Protozoology, Biochemistry, Pentose Phosphate Pathway, Citrate synthase, Malaria, Falciparum, lcsh:QH301-705.5, 0303 health sciences, Systems Biology, 3. Good health, Pyruvate carboxylase, Mitochondria, Acids, Acyclic, Phosphoenolpyruvate carboxylase, Research Article, lcsh:Immunologic diseases. Allergy, RM, Immunology, Citric Acid Cycle, Plasmodium falciparum, Biology, Pentose phosphate pathway, Microbiology, RS, 03 medical and health sciences, Virology, parasitic diseases, Genetics, Humans, Molecular Biology, 030304 developmental biology, 030306 microbiology, Wild type, Parasite Physiology, Metabolism, biology.organism_classification, Phosphoenolpyruvate Carboxylase, Citric acid cycle, Radiography, lcsh:Biology (General), biology.protein, Parastic Protozoans, Parasitology, lcsh:RC581-607, Genome, Protozoan

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b039978ef2bc9f997737c234bcb73cc6Test
http://europepmc.org/articles/PMC3894211?pdf=renderTest

5

Identification and analysis of putative homologues of mechanosensitive channels in pathogenic protozoa

المؤلفون: David L. Prole, Colin W. Taylor

المصدر: PLoS ONE, Vol 8, Iss 6, p e66068 (2013)
PLoS ONE

مصطلحات موضوعية: Anatomy and Physiology, Protozoan Proteins, lcsh:Medicine, Protozoology, Biochemistry, Mechanotransduction, Cellular, Ion Channels, Toxoplasma Gondii, Conserved sequence, Transmembrane Transport Proteins, Transient receptor potential channel, 0302 clinical medicine, Microbial Physiology, Molecular Cell Biology, lcsh:Science, Conserved Sequence, Phylogeny, Leishmania, 0303 health sciences, Multidisciplinary, biology, Mechanisms of Signal Transduction, Genomics, Functional Genomics, 3. Good health, Cell biology, Electrophysiology, Plasmodium Falciparum, Mechanosensitive channels, Research Article, Signal Transduction, Cell Physiology, Trypanosoma, Molecular Sequence Data, Sequence alignment, Microbiology, Entamoeba Histolytica, 03 medical and health sciences, Entamoeba histolytica, parasitic diseases, Animals, Parasites, Protein Interaction Domains and Motifs, Amino Acid Sequence, Trypanosoma cruzi, Biology, Microbial Pathogens, Gene, Ion channel, 030304 developmental biology, Giardia Lamblia, lcsh:R, Parasite Physiology, Proteins, biology.organism_classification, Transmembrane Proteins, Protein Subunits, Cellular Neuroscience, Parastic Protozoans, Parasitology, lcsh:Q, Sequence Alignment, 030217 neurology & neurosurgery, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2cf21e46736c66bdc8956a0c8b2cf7Test
http://europepmc.org/articles/PMC3681921?pdf=renderTest

6

Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs

المؤلفون: Gareth P. Williams, Deborah F. Smith, Tanya Parkinson, James Edward John Mills, James A. Brannigan, Anthony A. Holder, Andrew Simon Bell, Edward W. Tate, Anthony J. Wilkinson, Robin J. Leatherbarrow

المصدر: PLoS Neglected Tropical Diseases, Vol 6, Iss 4, p e1625 (2012)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: PARASITES, Drug Evaluation, Preclinical, Protozoan Proteins, Pharmacology, 01 natural sciences, Enzyme Inhibitors, 0303 health sciences, MYRISTOYL-COA, PLASMODIUM-FALCIPARUM, Molecular Structure, biology, TROPICAL MEDICINE, lcsh:Public aspects of medicine, 3. Good health, Chemistry, TARGET, Infectious Diseases, LEADS, Drug development, TRYPANOSOMA-BRUCEI, Life Sciences & Biomedicine, Research Article, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, High-throughput screening, Plasmodium falciparum, Trypanosoma brucei brucei, Antiprotozoal Agents, Leishmania donovani, Computational biology, Trypanosoma brucei, Public-Private Sector Partnerships, Microbiology, Structure-Activity Relationship, 03 medical and health sciences, MALARIA, parasitic diseases, medicine, Humans, DRUG DEVELOPMENT, Biology, 030304 developmental biology, Tropical Climate, Science & Technology, Protozoan Infections, 010405 organic chemistry, Parasite Physiology, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, biology.organism_classification, medicine.disease, Leishmania, 0104 chemical sciences, Emerging Infectious Diseases, Visceral leishmaniasis, DISCOVERY, Trypanosoma, VISCERAL LEISHMANIASIS, Parasitology, Medicinal Chemistry, Acyltransferases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83a3aab1c7d9a560a8dfd5dbad06500Test
http://europepmc.org/articles/PMC3335879?pdf=renderTest

7

Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum

المؤلفون: Paul R. Gilson, Roseli França Simões, Jacob Baum, Mauro F Azevedo, Heloisa B. Gabriel, Gerhard Wunderlich, Fiona Angrisano, Brendan S. Crabb

المصدر: PLoS ONE, Vol 7, Iss 7, p e40981 (2012)
PLoS ONE
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: Time Factors, Proteome, PARASITOLOGIA, Protozoan Proteins, lcsh:Medicine, Plasma protein binding, Protozoology, medicine.disease_cause, Biochemistry, Green fluorescent protein, Genes, Reporter, Molecular Cell Biology, lcsh:Science, Mutation, Multidisciplinary, Mechanisms of Signal Transduction, Transfection, Recombinant Proteins, Cell biology, FKBP, Research Article, Signal Transduction, Protein Binding, Green Fluorescent Proteins, Plasmodium falciparum, Biology, Microbiology, Tacrolimus Binding Proteins, medicine, Animals, Humans, Luciferase, Protein Interactions, lcsh:R, Parasite Physiology, Proteins, Signal Termination, biology.organism_classification, Molecular biology, Regulatory Proteins, Malaria, Protein Structure, Tertiary, Parastic Protozoans, Parasitology, lcsh:Q