دورية أكاديمية
Platelet Rich Plasma In Musculoskeletal Pathologies
| العنوان: | Platelet Rich Plasma In Musculoskeletal Pathologies |
|---|---|
| المؤلفون: | Kaniki, Nicole L |
| المصدر: | Electronic Thesis and Dissertation Repository |
| بيانات النشر: | Scholarship@Western |
| سنة النشر: | 2016 |
| المجموعة: | The University of Western Ontario: Scholarship@Western |
| مصطلحات موضوعية: | Platelet rich plasma, musculoskeletal injuries, ultrasound guided injections, tendon, muscle, plantar fasciitis, corticosteroid injections, Orthopedics, Other Rehabilitation and Therapy, Sports Medicine |
| الوصف: | Purpose: To evaluate the effectiveness of platelet rich plasma (PRP) in musculoskeletal injuries. Methods: We completed a review of the literature on the use of PRP in tendon, muscle, bone, and intra-articular injuries (Chapter 2). We completed a systematic review and meta-analysis on the effectiveness of PRP in ultrasound guided versus palpation guided injections of PRP in non-operative treatment of tendon and muscle injuries using an indirect analysis method (Chapter 3). We conducted a randomized controlled trial to determine the effectiveness of PRP versus corticosteroid (CS) injections in patients with plantar fasciitis (Chapter 4). Results: Most studies evaluating the effectiveness of PRP in musculoskeletal injuries are for the treatment of tendon and intra-articular injuries, with fewer studies assessing its effectiveness in muscle and bone healing. The published studies included in the review had a heterogenous summation of results that could not be used to conclusively determine the superiority of PRP over other treatments for musculoskeletal injuries. We included 26 studies in our systematic review to compare ultrasound versus palpation guided injections of PRP. We found no statistically significant difference between ultrasound versus palpation guided injections for failure rates and pain outcomes at two months, two to three months, and six months following injection (p > 0.05). The comparison of functional outcomes at six months showed a significant effect in favor of palpation guided injections (p = 0.01), but heterogeneity of the analysis was high (I2= 83.5%) and we were unable to make any definitive conclusions on the results. In our RCT, we found no statistically significant difference between PRP versus CS injections for our primary outcome of pain and function using the American Orthopaedic Foot and Ankle Society Ankle-hindfoot scale, at six months or one year. We also found no statistically significant difference for all other outcomes at six months and one year. Conclusion: The results in ... |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://ir.lib.uwo.ca/etd/3752Test; https://ir.lib.uwo.ca/context/etd/article/5170/viewcontent/auto_convert.pdfTest |
| الإتاحة: | https://ir.lib.uwo.ca/etd/3752Test https://ir.lib.uwo.ca/context/etd/article/5170/viewcontent/auto_convert.pdfTest |
| رقم الانضمام: | edsbas.29E4D196 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |