التفاصيل البيبلوغرافية
| العنوان: |
Stereoselective Synthesis of Dihydrocoumarins via [1,2]-Phospha-Brook Rearrangement in Three-Component Coupling Reaction of α‑Ketoesters, o ‑Quinone Methides, and Dialkyl Phosphites |
| المؤلفون: |
Ravneet Kaur (3714880), Dipak Singh (11552736), Ravi P. Singh (1849204) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Microbiology, Molecular Biology, Physiology, Evolutionary Biology, Sociology, Plant Biology, Computational Biology, pot michael addition, phosphonyloxy enolates proceeds, >‑ quinone methides, >- quinone methides, 2 ]- phospha, component coupling reaction, α ‑ ketoesters, providing 3, intramolecular cyclization, highly regio, dihydrocoumarins via, dihydrocoumarin frameworks, diastereoselective approach, dialkyl phosphites, dialkyl phosphite, brook rearrangement |
| الوصف: |
A highly regio- and diastereoselective approach for the synthesis of phosphate substituted dihydrocoumarins via Brønsted base catalyzed [1,2]-phospha-Brook rearrangement is reported. The two-step, one-pot Michael addition of α-phosphonyloxy enolates proceeds by coupling of dialkyl phosphite and α-ketoesters to o -quinone methides, followed by an intramolecular cyclization, providing 3,4-dihydrocoumarin frameworks. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/journal_contribution/Stereoselective_Synthesis_of_Dihydrocoumarins_via_1_2_-Phospha-Brook_Rearrangement_in_Three-Component_Coupling_Reaction_of_Ketoesters_i_o_i_Quinone_Methides_and_Dialkyl_Phosphites/16798173Test |
| DOI: |
10.1021/acs.joc.1c01414.s001 |
| الإتاحة: |
https://doi.org/10.1021/acs.joc.1c01414.s001Test |
| حقوق: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.CDEB6010 |
| قاعدة البيانات: |
BASE |
