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المؤلفون: Anne T. Nies, Elke Schaeffeler, Kathrin Klein, Kathleen M. Giacomini, Michel Eichelbaum, Matthias Schwab, Ute Hofmann, Claudia Neul, Stefan Winter
المصدر: British Journal of Pharmacology. 178:1459-1474
مصطلحات موضوعية: 0301 basic medicine, CYP2D6, SLC47A1, Organic Cation Transport Proteins, Pharmacology, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cations, medicine, Humans, Organic cation transport proteins, biology, Chemistry, Sparteine, Organic Cation Transporter 2, Cytochrome P450, Phenotype, 030104 developmental biology, Cytochrome P-450 CYP2D6, Pharmaceutical Preparations, Debrisoquine, Perhexiline, biology.protein, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3555d075053f2fad1daf3c8541155Test
https://doi.org/10.1111/bph.15370Test -
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المؤلفون: Adrián LLerena, Andrea Gaedigk, Robert L. Smith, Julia C. Stingl, Michel Eichelbaum, R R Shah
المصدر: Pharmacogenomics. 17:259-275
مصطلحات موضوعية: Genotype, Biology, Bioinformatics, Risk Assessment, 030226 pharmacology & pharmacy, Substrate Specificity, 03 medical and health sciences, 0302 clinical medicine, Cytochrome P-450 Enzyme System, Gene Frequency, Genetics, medicine, Humans, Allele, Allele frequency, Genetic Association Studies, Genetic association, Pharmacology, medicine.diagnostic_test, Phenotype, Pharmacogenetics, Research Design, Therapeutic drug monitoring, 030220 oncology & carcinogenesis, Molecular Medicine, Drug Monitoring, Imputation (genetics)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cba0468706f4763d99af9b8fa1ce81Test
https://doi.org/10.2217/pgs.15.172Test -
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المؤلفون: Max Groome, Christopher Day, Camilla Stephens, Raúl J. Andrade, Matthew R. Nelson, Manuel Romero-Gómez, Ann K. Daly, Anita Conforti, Guruprasad P. Aithal, Thomas J. Urban, Michael H Miller, Francisco Ruiz-Cabello, Emmanuelle Bondon-Guitton, Yufeng Shen, J.M. Navarro, Mark J. Daly, David Goldstein, Luisa Ibáñez, Aris Floratos, Alfonso Carvajal, Mariam Molokhia, M. Isabel Lucena, Robert J. Fontana, Qun-Ying Yue, Bruno H. Ch. Stricker, Paul B. Watkins, Michel Eichelbaum, Peter T. Donaldson, Itsik Pe'er, John F. Dillon, Munir Pirmohamed
المساهمون: Epidemiology
المصدر: Gastroenterology, 141(1), 338-347. W.B. Saunders
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instnameمصطلحات موضوعية: Male, Linkage disequilibrium, Genes, MHC Class I, Genome-wide association study, Adaptive Immunity, 0302 clinical medicine, Gene Frequency, Risk Factors, Odds Ratio, HLA-DQ beta-Chains, Registries, Genetics, Aged, 80 and over, 0303 health sciences, education.field_of_study, Gastroenterology, Tag SNP, Middle Aged, 3. Good health, Anti-Bacterial Agents, Europe, Phenotype, 030211 gastroenterology & hepatology, Female, Chemical and Drug Induced Liver Injury, Population, Genes, MHC Class II, Single-nucleotide polymorphism, Human leukocyte antigen, Biology, Amoxicillin-Potassium Clavulanate Combination, Polymorphism, Single Nucleotide, Risk Assessment, White People, Article, 03 medical and health sciences, HLA-DQ Antigens, Genetic predisposition, SNP, Humans, Genetic Predisposition to Disease, education, 030304 developmental biology, Aged, Chi-Square Distribution, Hepatology, HLA-A Antigens, HLA-DR Antigens, United States, Logistic Models, Haplotypes, Case-Control Studies, Immunology, Amoxicilina - Efectos secundarios, Genome-Wide Association Study, HLA-DRB1 Chains
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff544996ee77d5c589770728976532Test
https://hdl.handle.net/1765/33370Test -
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المؤلفون: Klaus Moerike, Elke Schaeffeler, Ulrich M. Zanger, Dierk Brockmeier, Dorothee Wernet, Michel Eichelbaum, Christine Fischer, Matthias Schwab
المصدر: Pharmacogenetics. 14:407-417
مصطلحات موضوعية: Adult, Erythrocytes, Adolescent, Genotype, Population, Biology, White People, Thiopurine S-Methyltransferase, Polymorphism (computer science), Germany, Genetics, Humans, General Pharmacology, Toxicology and Pharmaceutics, education, Genotyping, Aged, Sex Characteristics, education.field_of_study, Thiopurine methyltransferase, Smoking, Genetic Variation, Methyltransferases, Middle Aged, Kinetics, Phenotype, biology.protein, Population study, Female, Pharmacogenetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38614fc424a9454c868940d2157e0d66Test
https://doi.org/10.1097/01.fpc.0000114745.08559.dbTest -
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المؤلفون: Peter Fritz, Elke Schaeffeler, Horst Halle, Martin F. Fromm, Berthold Hocher, Torsten Slowinski, Monika Hitzl, Peter Kaufmann, Michel Eichelbaum, Matthias Schwab
المصدر: Pharmacogenetics. 14:309-318
مصطلحات موضوعية: Male, Genotype, Placenta, Andrology, Exon, Pregnancy, Genetics, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, General Pharmacology, Toxicology and Pharmaceutics, Allele, DNA Primers, P-glycoprotein, Fetus, Microscopy, Confocal, Base Sequence, biology, Haplotype, Infant, Newborn, Immunohistochemistry, Phenotype, medicine.anatomical_structure, Mutation, Immunology, biology.protein, Female, Genes, MDR, Pharmacogenetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bd434fab5385daa4493ac8008dba81Test
https://doi.org/10.1097/00008571-200405000-00006Test -
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المؤلفون: Martin F. Fromm, Matthias Schwab, Michel Eichelbaum
المصدر: Therapeutic Drug Monitoring. 26:180-185
مصطلحات موضوعية: CYP2D6, Population, Single-nucleotide polymorphism, ATP-binding cassette transporter, Antidepressive Agents, Tricyclic, Biology, Pharmacology, Polymorphism, Single Nucleotide, Cardiac Glycosides, Gene duplication, polycyclic compounds, Animals, Humans, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, education, Gene, Loss function, Genetics, education.field_of_study, Polymorphism, Genetic, Abnormalities, Drug-Induced, HIV Protease Inhibitors, Phenotype, Mutation, Genes, MDR, Immunosuppressive Agents
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1481c70bf110f0829c37df9ac5f965Test
https://doi.org/10.1097/00007691-200404000-00017Test -
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المؤلفون: Sebastian Raimundo, Ulrich M. Zanger, Matthias Schwab, Thomas Stüven, Joachim Fischer, Bernd Evert, Michel Eichelbaum
المصدر: Pharmacogenetics. 11:573-585
مصطلحات موضوعية: Polymorphism, Genetic, Genotype, Immunoblotting, Bufuralol, Gene Dosage, Biology, Phenotype, Molecular biology, Gene dosage, Recombinant Proteins, Isoenzymes, Variable Expression, chemistry.chemical_compound, Cytochrome P-450 CYP2D6, Liver, chemistry, Polymorphism (computer science), Gene expression, Genetics, Humans, General Pharmacology, Toxicology and Pharmaceutics, Allele, Promoter Regions, Genetic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1d6cfbdd9224734a2c54ede250ad4eTest
https://doi.org/10.1097/00008571-200110000-00004Test -
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المؤلفون: Ulrich M. Zanger, Michel Eichelbaum, Joachim Fischer, Sebastian Raimundo, Matthias Schwab, Ernst-Ulrich Griese
المصدر: Pharmacogenetics. 10:577-581
مصطلحات موضوعية: Male, CYP2D6, Genotype, Sparteine, Population, Biology, digestive system, Genetics, Humans, General Pharmacology, Toxicology and Pharmaceutics, Allele, skin and connective tissue diseases, education, Gene, Genotyping, DNA Primers, education.field_of_study, Base Sequence, Pedigree, Phenotype, Cytochrome P-450 CYP2D6, Mutation, Mutation (genetic algorithm), Female, Oxidation-Reduction, Pharmacogenetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd61e8403c30b9bedad1456bf9e7375Test
https://doi.org/10.1097/00008571-200010000-00001Test -
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المؤلفون: B. Sperker, Heyo K. Kroemer, P. Schwarzmann, Kari T. Kivistö, M. Spath, Peter Fritz, T. E. Murdter, Michel Eichelbaum
المصدر: Xenobiotica. 29:693-702
مصطلحات موضوعية: Adult, Male, Cytoplasm, Health, Toxicology and Mutagenesis, Blotting, Western, Biology, Toxicology, Biochemistry, Reference Values, Biopsy, medicine, Humans, neoplasms, Aged, Glutathione Transferase, Pharmacology, Paraffin Embedding, integumentary system, medicine.diagnostic_test, Liver Diseases, Reproducibility of Results, Cancer, General Medicine, Middle Aged, medicine.disease, Hodgkin Disease, Immunohistochemistry, Phenotype, Molecular biology, Staining, Fatty Liver, Blot, Glutathione S-transferase, Liver, biology.protein, Female, Antibody
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ee10d6d13fec3a985b7058be5461baTest
https://doi.org/10.1080/004982599238326Test -
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المؤلفون: Gerhard Schänzle, Klaus Eckhardt, Gerd Mikus, Shuxia Li, Michel Eichelbaum, Susanne Ammon
المصدر: Pain. 76:27-33
مصطلحات موضوعية: Adult, Male, Genotype, Metabolite, Analgesic, Population, Cmax, Pharmacology, chemistry.chemical_compound, Double-Blind Method, Pharmacokinetics, Humans, Medicine, education, Pain Measurement, education.field_of_study, Morphine, Codeine, business.industry, Analgesics, Opioid, Phenotype, Anesthesiology and Pain Medicine, Cytochrome P-450 CYP2D6, Neurology, Opioid, chemistry, Area Under Curve, Female, Neurology (clinical), business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db466013e2310322be7586f5a1a365c3Test
https://doi.org/10.1016/s0304-3959Test(98)00021-9