نتائج البحث - "phorbol 12-myristate 13-acetate"

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Functional metabolomics reveal the role of AHR/GPR35 mediated kynurenic acid gradient sensing in chemotherapy-induced intestinal damage

المؤلفون: Chuyao Liao, Di Wang, Ying Zhang, Zunjian Zhang, Fengguo Xu, Siyuan Qin, Yuxin Zhang, Danting Li, Yuan Tian, Jie Chen

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 763-780 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: CYP1A1, cytochrome P450 1A1, PF, PF-04859989, MOE, molecular operating environment, MTT, thiazolyl blue tetrazolium bromide, Kynurenine pathway, RPKM, reads per kilobase per million mapped reads, STAT3, signal transducer and activator of transcription 3, KAT, kynurenine aminotransferase, AHR, GPR35, G protein-coupled receptor 35, HRP, horseradish peroxi-dase, KA, kynurenic acid, RIPA, radioimmunoprecipitation, DMSO, dimethyl sulfoxide, ECL, enhanced chemiluminescence, Pharmacology, DPP-4, dipeptidyl peptidase-4, PDE5, phosphodiesterase type-5, RT-PCR, real-time polymerase chain reaction, CPT-11, irinotecan, AHR, aryl hydrocarbon receptor, chemistry.chemical_compound, DSS, dextran sulphate sodium, Intestinal toxicity, 0302 clinical medicine, Kynurenic acid, DRE, dioxin response elements, CH, CH223191, LC–MS, liquid chromatography–mass spectrometry, IS, internal standard, VCR, vincristine, General Pharmacology, Toxicology and Pharmaceutics, GE, gastric emptying, IL-6, interleukin-6, PDB, protein data bank, Receptor, GFP, green fluorescence protein, MOI, multiplicity of infection, 0303 health sciences, ESI, electrospray ionization, IBD, inflammatory bowel disease, HE, hematoxylin and eosin, ELISA, enzyme-linked immunosorbent assay, 030220 oncology & carcinogenesis, IDO1, indoleamine 2,3-dioxygenase 1, Original Article, 1-MT, 1-methyl-tryptophan, DAI, disease activity index, RPMI 1640, Roswell Park Memorial Institute 1640, medicine.symptom, GPR35, medicine.drug, PMA, phorbol 12-myristate 13-acetate, Linag, linagliptin, Trp, tryptophan, Dens-Cl, N-diethyl-amino naphthalene-1-sulfonyl chloride, Inflammation, AG, AG490, Linagliptin, Dns-Cl, N-dimethyl-amino naphthalene-1-sulfonyl chloride, 03 medical and health sciences, PBS, phosphate buffer saline, FBS, fetal bovine serum, Downregulation and upregulation, GI, gastrointestinal transit, Vard, vardenafil, Gradually sensing, medicine, 030304 developmental biology, MRM, multiple-reaction monitoring, lcsh:RM1-950, KYN, kynurenine, BCA, bicinchoninic acid, lcsh:Therapeutics. Pharmacology, PMSF, phenylmethylsulfonyl fluoride, chemistry, ARNT, aryl hydrocarbon receptor nuclear translocator, ERK1/2, extracellular regulated protein kinases 1/2, LPS, lipopolysaccharides, BSA, bovine serum albumin, JAK2, janus kinase 2, Homeostasis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af930bc5ea3c9fbae9d582539b35a5fTest
https://doi.org/10.1016/j.apsb.2020.07.017Test

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Regulatory Effect of Cannabidiol (CBD) on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells

المؤلفون: Keun-Cheol Kim, Byung-Soo Ahn, Hyun Suk Jung, Han-Heom Na, Yoon-Jong Park, Jin Sung Park, Jae-Min Ryu, Bok-hye Kim

المصدر: Journal of Pharmacopuncture
Journal of Pharmacopuncture, Vol 24, Iss 2, Pp 68-75 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fd5bbcf3a59e632bf06ab2fbde33b1Test
https://pubmed.ncbi.nlm.nih.gov/34249397Test

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In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH2 and Lau-(Lys-βNspe)6-NH2 Against PMA-Induced Acute Inflammation

المؤلفون: Bing C Wu, Henrik Franzyk, Sarah L Skovbakke, Hamid Masoudi, Robert E. W. Hancock

المصدر: Frontiers in Immunology, Vol 11 (2020)
Wu, B C, Skovbakke, S L, Masoudi, H, Hancock, R E W & Franzyk, H 2020, ' In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe) 6-NH 2 and Lau-(Lys-βNspe) 6-NH 2 Against PMA-Induced Acute Inflammation ', Frontiers in Immunology, vol. 11, 2102 . https://doi.org/10.3389/fimmu.2020.02102Test
Frontiers in Immunology
Wu, B C, Skovbakke, S L, Masoudi, H, Hancock, R E W & Franzyk, H 2020, ' In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH 2 and Lau-(Lys-βNspe)6-NH 2 Against PMA-Induced Acute Inflammation ', Frontiers in Immunology, vol. 11, 2102 . https://doi.org/10.3389/fimmu.2020.02102Test

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Phorbol 12-myrisates 13-acetate, medicine.drug_class, Peptidomimetic, medicine.medical_treatment, Immunology, Inflammation, Pharmacology, Anti-inflammatory, Formyl peptide receptor 2, formyl peptide receptors, 03 medical and health sciences, 0302 clinical medicine, Immune system, neutrophils, In vivo, medicine, Immunology and Allergy, reactive oxygen and nitrogen species, Original Research, 030304 developmental biology, anti-inflammatory, 0303 health sciences, Neutrophilis, Innate immune system, Chemistry, 3. Good health, Peptidomimetrics, Cytokine, sterile inflammation, 030220 oncology & carcinogenesis, peptidomimetics, medicine.symptom, lcsh:RC581-607, edema, phorbol 12-myristate 13-acetate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0589f01ddf3feddaca1dd91c6a745b1Test
https://www.frontiersin.org/article/10.3389/fimmu.2020.02102/fullTest

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Re-Du-Ning injection ameliorates LPS-induced lung injury through inhibiting neutrophil extracellular traps formation

المؤلفون: Ling-Dong Kong, Haibo Li, Chenglin Song, Wei Xiao, Wen Lv, Hui Ming Ge, Jiao Qu, Yang Sun, Yitong Liu, Chenxi Yang

المصدر: Phytomedicine

مصطلحات موضوعية: Lipopolysaccharides, MAPK/ERK pathway, ARDS, medicine.medical_treatment, MAPK, Mitogen-activated protein kinase, ERK1/2, Extracellular signal regulated kinases, i.p, Intraperitoneal injection, Pharmaceutical Science, TNF-α, Tumor necrosis factor α, Pharmacology, GM-CSF, Granulocyte-macrophage Colony Stimulating Factor, Extracellular Traps, Dex, Dexamethasone, Mice, H&E., Hematoxylin-eosin, 0302 clinical medicine, BALF, bronchoalveolar lavage fluid, Drug Discovery, Re-Du-Ning injection, Respiratory system, LPS, Lipopolysaccharide, Lung, 0303 health sciences, medicine.diagnostic_test, Blot, ELISA, Enzyme-linked immunosorbent assay, COVID-19, Coronavirus Disease 2019, 030220 oncology & carcinogenesis, Molecular Medicine, RDN, Re-Du-Ning injection, Female, PMA, phorbol 12-myristate 13-acetate, IL-1β, Interleukin (IL)-1β, NETs, neutrophil extracellular traps, MPO, Myeloperoxidase, Acute Lung Injury, Intraperitoneal injection, PAD4, peptidyl arginine deiminase 4, Lung injury, Immunofluorescence, Article, cit H3, Citrullinated histone H3, IL-6, Interleukin (IL)-6, 03 medical and health sciences, IL-17A, Interleukin (IL)-17A, ARDS, Acute respiratory distress syndrome, medicine, NE, neutrophil elastase, Animals, 030304 developmental biology, business.industry, ALI, Acute lung injury, NETs, Neutrophil extracellular traps, medicine.disease, MAPK, Mice, Inbred C57BL, ALI, Complementary and alternative medicine, business, Drugs, Chinese Herbal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cee0a743021f3ae89f6003c6426ca2Test
https://doi.org/10.1016/j.phymed.2021.153635Test

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Eupatilin downregulates phorbol 12-myristate 13-acetate-induced MUC5AC expression via inhibition of p38/ERK/JNK MAPKs signal pathway in human airway epithelial cells

المؤلفون: Yoon-Hee Cheon, Jae Hoon Lee, Ju-Young Kim, Min Seob Kim, Dong Hyun Kim, Seung Yoon Han

المصدر: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology