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المساهمون: National Natural Science Foundation of China, National Key Research and Development Program of China, Innovative Research Team of High-level Local Universities in Shanghai

المصدر: Inflammation Research ; volume 72, issue 4, page 797-812 ; ISSN 1023-3830 1420-908X

مصطلحات موضوعية: Pharmacology, Immunology

الإتاحة: https://doi.org/10.1007/s00011-023-01713-3Test

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6

Thioridazine Induces Cardiotoxicity via Reactive Oxygen Species-Mediated hERG Channel Deficiency and L-Type Calcium Channel Activation

المؤلفون: Yuhao Zhang, Xue-Qi Xu, Mingzhu Li, Baoxin Li, Fang Wang, Yan Liu, Jiamengyi Guo, Pan Fan, Yun-Qi Ding, Yuexin Li, Cai-Chuan Yan

المصدر: Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity

مصطلحات موضوعية: Male, 0301 basic medicine, Benzylamines, Proteasome Endopeptidase Complex, Aging, Calcium Channels, L-Type, Article Subject, Heart Ventricles, Induced Pluripotent Stem Cells, hERG, Action Potentials, Thio, 030204 cardiovascular system & hematology, Pharmacology, Biochemistry, Afterdepolarization, Mice, 03 medical and health sciences, 0302 clinical medicine, Ca2+/calmodulin-dependent protein kinase, Animals, Humans, HSP70 Heat-Shock Proteins, Myocytes, Cardiac, L-type calcium channel, Patch clamp, Sulfonamides, QH573-671, biology, Voltage-dependent calcium channel, Thioridazine, Chemistry, Calcium channel, Ubiquitination, Cell Biology, General Medicine, Endoplasmic Reticulum Stress, Cardiotoxicity, Ether-A-Go-Go Potassium Channels, Rats, HEK293 Cells, 030104 developmental biology, biology.protein, Calcium, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Reactive Oxygen Species, Cytology, Research Article

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00144b0517bc3bb2b0c651075c65c4acTest
https://doi.org/10.1155/2020/3690123Test

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Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro

المؤلفون: Yuan-Qi Shi, Yuhao Zhang, Baoxin Li, Fang Wang, Mingzhu Li, Guocui Zhang, Pan Fan

المصدر: Current Pharmaceutical Design

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Patch-Clamp Techniques, Long QT syndrome, hERG, Probucol, Pharmacology, Article, Cell Line, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Transactivation, 0302 clinical medicine, matrine, Alkaloids, Matrine, Drug Discovery, medicine, Myocyte, Animals, Humans, Myocytes, Cardiac, cardiovascular diseases, oxymatrine, specificity protein 1, Matrines, 030304 developmental biology, 0303 health sciences, biology, medicine.disease, Potassium channel, Ether-A-Go-Go Potassium Channels, Oxymatrine, chemistry, 030220 oncology & carcinogenesis, biology.protein, cardiac repolarization, Human ether-a-go-go-related gene, Quinolizines, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6523203b32dbe036ccbcb75a020ba124Test
http://europepmc.org/articles/PMC7327797Test

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A Traditional Chinese Medicine Plant Extract Prevents Alcohol-Induced Osteopenia

المؤلفون: Dongyang Qian, Hui Zhou, Pan Fan, Tao Yu, Anish Patel, Morgan O’Brien, Zhe Wang, Shiguang Lu, Guoqiang Tong, Yimin Shan, Lei Wang, Yuan Gao, Yuan Xiong, Lily Zhang, Xin Wang, Yuancai Liu, Shuanhu Zhou

المصدر: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology

مصطلحات موضوعية: Pharmacology, traditional Chinese medicine, alcohol-induced bone diseases, Pharmacology (medical), ethnopharmacology, Therapeutics. Pharmacology, RM1-950, osteoporosis, TCM herbal extracts, Original Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c362402c13123b9019c3a961ba8083c2Test
https://pubmed.ncbi.nlm.nih.gov/35002697Test

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دورية أكاديمية

DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages

المؤلفون: Xu, Xiaotao, Su, Yang, Wu, Kaixuan, Pan, Fan, Wang, Aizhong

المساهمون: National Natural Science Foundation of China

المصدر: Biochemical Pharmacology ; volume 184, page 114399 ; ISSN 0006-2952

مصطلحات موضوعية: Pharmacology, Biochemistry

الإتاحة: https://doi.org/10.1016/j.bcp.2020.114399Test
https://api.elsevier.com/content/article/PII:S0006295220306353?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0006295220306353?httpAccept=text/plainTest

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10

Stereoselective Blockage of Quinidine and Quinine in the hERG Channel and the Effect of Their Rescue Potency on Drug-Induced hERG Trafficking Defect

المؤلفون: Ge Zhan, Junnan Wang, Meng Yan, Pan Fan, Lifang Feng, Yanhui Shi, Baoxin Li

المصدر: International Journal of Molecular Sciences, Vol 17, Iss 10, p 1648 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 10; Pages: 1648

مصطلحات موضوعية: 0301 basic medicine, Quinidine, Drug, congenital, hereditary, and neonatal diseases and abnormalities, media_common.quotation_subject, hERG, 030204 cardiovascular system & hematology, Pharmacology, stereoselectivity, Catalysis, Article, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, quinidine, quinine, hERG (human ether-a-go-go-related gene), pharmacological rescue, medicine, Repolarization, Potency, cardiovascular diseases, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, media_common, Quinine, biology, Chemistry, Organic Chemistry, General Medicine, Potassium channel, Computer Science Applications, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, biology.protein, medicine.drug, Pentamidine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb55120f6761a80468572b2a9f8d6251Test
http://www.mdpi.com/1422-0067/17/10/1648Test

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