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المؤلفون: Suzanne F. Jones, Carla Kurkjian, Kathleen N. Moore, Howard A. Burris, Shubham Pant, Scott McMeekin, Ofir Moreno, Johanna C. Bendell, Jeffrey R. Infante, John G. Kuhn
المصدر: Investigational New Drugs
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Nausea, Colorectal cancer, Antineoplastic Agents, Apoptosis, tNOX, Pharmacology, Gastroenterology, Young Adult, Pharmacokinetics, Multienzyme Complexes, In vivo, Neoplasms, Phase I Studies, Internal medicine, medicine, Humans, Anal cancer, Benzopyrans, NADH, NADPH Oxidoreductases, ME-143, Pharmacology (medical), Enzyme Inhibitors, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, Dose escalation, business.industry, Middle Aged, medicine.disease, Isoflavone, Treatment Outcome, Oncology, Tolerability, Area Under Curve, Toxicity, Cohort, Female, medicine.symptom, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062b21323ed52cd82f147d1a0a459365Test
https://doi.org/10.1007/s10637-013-9949-4Test -
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المؤلفون: Gerard C. Blobe, Haiyan Li, Herbert Pang, Hope E. Uronis, Mark D. Starr, Michael A. Morse, Kellen L. Meadows, Andrew B. Nixon, Jon P. Gockerman, Herbert Hurwitz, Stephanie M. Cushman, Johanna C. Bendell, Andrew Dellinger
المصدر: Cancer Medicine
مصطلحات موضوعية: Placental growth factor, Adult, Male, Cancer Research, Bevacizumab, Angiogenesis, Angiogenesis Inhibitors, Pharmacology, bevacizumab, Antibodies, Monoclonal, Humanized, chemistry.chemical_compound, Young Adult, Von Willebrand factor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Radiology, Nuclear Medicine and imaging, Aged, biology, Dose-Response Relationship, Drug, business.industry, Clinical Cancer Research, ABT-510, phase I, Middle Aged, Angiogenesis inhibitor, Vascular endothelial growth factor, Oncology, chemistry, Tolerability, biology.protein, Female, advanced solid tumors, business, Oligopeptides, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e2a2af1680acac1e741f063d211fcfTest
http://europepmc.org/articles/PMC3699843Test -
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المؤلفون: Vicki L. Keedy, Emily Chan, Wooin Lee, Hiroshi Kodaira, William C. Zamboni, Huali Wu, Johanna C. Bendell, Howard A. Burris, Jeffrey R. Infante, Satoshi Ikeda, Mace L. Rothenberg, Suzanne F. Jones
المصدر: Cancer Chemotherapy and Pharmacology. 70:699-705
مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Maximum Tolerated Dose, Nausea, Neutropenia, Irinotecan, Toxicology, Gastroenterology, Polyethylene Glycols, Pharmacokinetics, Neoplasms, Internal medicine, medicine, Humans, Pharmacology (medical), Dosing, Glucuronosyltransferase, Adverse effect, Aged, Pharmacology, Dose-Response Relationship, Drug, business.industry, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Pegylated Liposomal Irinotecan, Treatment Outcome, Oncology, Liposomes, Vomiting, Camptothecin, Female, medicine.symptom, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c33a78af5b551f242910ec16ea5fe04Test
https://doi.org/10.1007/s00280-012-1960-5Test -
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المؤلفون: Ron Yu, Jeffrey R. Infante, Walter C. Darbonne, Harvey Wong, Chia C. Portera, Anthony W. Tolcher, Howard A. Burris, Wayne J. Fairbrother, Franklin Peale, Stephanie Royer-Joo, Amita Patnaik, Kyriakos P. Papadopoulos, Johanna C. Bendell, Nageshwar Budha, Michael Mamounas
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 22(18)
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Nausea, Administration, Oral, Antineoplastic Agents, Pharmacology, Inhibitor of Apoptosis Proteins, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Neoplasms, medicine, Humans, Dosing, Adverse effect, Pneumonitis, Aged, Aged, 80 and over, business.industry, Middle Aged, medicine.disease, Rash, 030104 developmental biology, Treatment Outcome, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Pharmacodynamics, Retreatment, Vomiting, Cytokines, Female, medicine.symptom, business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83486f46af14faa264dd9e8ad46e2d1bTest
https://pubmed.ncbi.nlm.nih.gov/27076626Test -
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المؤلفون: Noriko Watanabe, Dana S. Thompson, F. Anthony Greco, Johanna C. Bendell, Suzanne F. Jones, Jeffrey R. Infante, Howard A. Burris, Yoshihiro Nambu, John H. Barton
المصدر: Cancer chemotherapy and pharmacology. 77(5)
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Maximum Tolerated Dose, Polymers, medicine.medical_treatment, SN-38, Pharmacology, Toxicology, Irinotecan, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Neoplasms, Medicine, Humans, Pharmacology (medical), Glucuronosyltransferase, Infusions, Intravenous, Active metabolite, Micelles, Aged, Chemotherapy, Drug Carriers, Dose-Response Relationship, Drug, business.industry, Homozygote, Middle Aged, Antineoplastic Agents, Phytogenic, Regimen, 030104 developmental biology, Oncology, chemistry, Tolerability, 030220 oncology & carcinogenesis, Area Under Curve, Toxicity, Camptothecin, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9159f530a4c1f5448ed81b317a0397Test
https://pubmed.ncbi.nlm.nih.gov/27061418Test -
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المؤلفون: Lee M. Krug, Howard A. Burris, Hartmut Koeppen, Johanna C. Bendell, Tanguy Y. Seiwert, Saoirse Dolly, Martijn P. Lolkema, Ru Fang Yeh, Marjorie G. Zauderer, Andrew J. Wagner, Doris Apt, Hedy L. Kindler, Joseph A. Ware, Johann S. de Bono, Jennifer O. Lauchle, Jill Fredrickson, Jill M. Spoerke
المساهمون: Medical Oncology
المصدر: Clinical Cancer Research, 22(12), 2874-2884. American Association for Cancer Research Inc.
مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Class I Phosphatidylinositol 3-Kinases, Antineoplastic Agents, Pharmacology, Article, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Neoplasms, medicine, Maculopapular rash, Humans, Protein Kinase Inhibitors, Pneumonitis, business.industry, TOR Serine-Threonine Kinases, Cancer, Middle Aged, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Rash, 030104 developmental biology, Pyrimidines, Oncology, Tolerability, 030220 oncology & carcinogenesis, Pharmacodynamics, Peritoneal mesothelioma, Female, medicine.symptom, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f6e915271a68e44b45291a59dc13bTest
https://pubmed.ncbi.nlm.nih.gov/26787751Test -
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المؤلفون: James M. Cleary, Kristen J. Pierce, Shuchi Sumant Pandya, Philippe L. Bedard, Albiruni Ryan Abdul Razak, Geoffrey I. Shapiro, Johanna C. Bendell, Suzanne F. Jones, S. Martin Shreeve, Lillian L. Siu, W. Gregory Roberts, Jeffrey R. Infante, Brett E. Houk
المصدر: Investigational new drugs. 33(5)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Maximum Tolerated Dose, Nausea, Antineoplastic Agents, Gastroenterology, Drug Administration Schedule, Food-Drug Interactions, Pharmacokinetics, Internal medicine, Neoplasms, medicine, Humans, Pharmacology (medical), Dosing, Organic Chemicals, Adverse effect, Unconjugated hyperbilirubinemia, Aged, Pharmacology, Sulfonamides, Dose-Response Relationship, Drug, business.industry, Half-life, Middle Aged, Diarrhea, Oncology, Anesthesia, Area Under Curve, Pyrazines, Benzamides, Vomiting, Female, medicine.symptom, business, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c914cf49f2e937624da28ef4c123d495Test
https://pubmed.ncbi.nlm.nih.gov/26334219Test -
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المؤلفون: A. Craig Lockhart, Konstanze Diefenbach, David Smith, Kathleen N. Moore, Robin L. Jones, Oliver Boix, Johanna C. Bendell, John Lettieri, Cindy L. O'Bryant
المصدر: Cancer chemotherapy and pharmacology. 76(4)
مصطلحات موضوعية: Diarrhea, Male, Mucositis, Cancer Research, medicine.medical_specialty, Pyridines, Heart Ventricles, Antineoplastic Agents, Toxicology, QT interval, Cardiotoxins, Severity of Illness Index, chemistry.chemical_compound, Electrocardiography, Internal medicine, Regorafenib, Neoplasms, Severity of illness, Clinical endpoint, medicine, Humans, Pharmacology (medical), Protein Kinase Inhibitors, Aged, Pharmacology, Ejection fraction, medicine.diagnostic_test, business.industry, Phenylurea Compounds, Stroke Volume, Stroke volume, Drugs, Investigational, Middle Aged, medicine.disease, Oncology, chemistry, Cardiovascular Diseases, Cardiology, Female, Drug Eruptions, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551057110d451e71319d3e8e1d00ed99Test
https://pubmed.ncbi.nlm.nih.gov/26281907Test -
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المؤلفون: Vicki L. Keedy, Howard A. Burris, Emily Chan, Johanna C. Bendell, Satoshi Ikeda, Beth A. Zamboni, Hiroshi Kodaira, Mace L. Rothenberg, Jeffrey R. Infante, Whitney P Kirschbrown, Huali Wu, Wooin Lee, Suzanne F. Jones, William C. Zamboni
المصدر: International Journal of Nanomedicine
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Biophysics, Pharmaceutical Science, Bioengineering, Antineoplastic Agents, Pharmacology, Irinotecan, Gastroenterology, Polyethylene Glycols, Biomaterials, Pharmacokinetics, Patient age, International Journal of Nanomedicine, Internal medicine, Neoplasms, Drug Discovery, medicine, Humans, In patient, Aged, business.industry, Organic Chemistry, General Medicine, Middle Aged, Pegylated Liposomal Irinotecan, Phase i study, Liposomes, Absolute neutrophil count, Camptothecin, Female, business, Corrigendum, Nadir (topography), medicine.drug
وصف الملف: text/html
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1578438171b08058c8bbfc79e72e06dTest
https://pubmed.ncbi.nlm.nih.gov/31413572Test -
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المؤلفون: Johanna C. Bendell, Grace K. Dy, Karim A. Benhadji, Alex A. Adjei, Jeffrey R. Infante, Gerald J. Fetterly, Wen Wee Ma, Sophie Callies
المصدر: Investigational new drugs. 33(2)
مصطلحات موضوعية: Male, medicine.medical_specialty, Maximum Tolerated Dose, Antineoplastic Agents, Gastroenterology, Drug Administration Schedule, Capecitabine, Pharmacokinetics, Internal medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pharmacology (medical), Drug Interactions, Prodrugs, Aged, Pharmacology, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Drug holiday, Middle Aged, medicine.disease, Deoxyuridine, Gemcitabine, Clinical trial, Oncology, Anesthesia, Toxicity, Female, Hyponatremia, business, Progressive disease, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c2b440974e97113dd3bb0f1358686dTest
https://pubmed.ncbi.nlm.nih.gov/25640850Test