يعرض 1 - 10 نتائج من 11 نتيجة بحث عن '"Clarissa A. Gurgel Rocha"', وقت الاستعلام: 0.77s تنقيح النتائج
  1. 1
    Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid leukemia HL-60 cells

    المؤلفون: Milena Botelho Pereira Soares, Ludmila de Faro Valverde, Hector H. F. Koolen, Emmanoel V. Costa, Daniel P. Bezerra, Rosane Borges Dias, Clarissa Araújo Gurgel Rocha, Felipe M. A. da Silva, Larissa M. Bomfim, Ana Carolina B. da C. Rodrigues, Waldireny Caldas Rocha, Sara P. Neves

    المصدر: Biomedicine & Pharmacotherapy, Vol 142, Iss, Pp 112034-(2021)

    مصطلحات موضوعية: Programmed cell death, MAP Kinase Signaling System, p38 mitogen-activated protein kinases, Down-Regulation, Apoptosis, HL-60 Cells, RM1-950, p38 Mitogen-Activated Protein Kinases, Antioxidants, Cell Line, Tingenone, Mice, Thioredoxins, AML, Salacia, 22-hydroxytingenone, Cell Line, Tumor, Animals, Humans, DNA Breaks, Double-Stranded, Fragmentation (cell biology), Thioredoxin, Pharmacology, Chemistry, Cell growth, Myeloid leukemia, General Medicine, Molecular biology, Antineoplastic Agents, Phytogenic, Triterpenes, Leukemia, Myeloid, Acute, Oxidative Stress, Cancer cell, Therapeutics. Pharmacology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad31df2fc91f85eda7c39224fdd61f74Test
    https://pubmed.ncbi.nlm.nih.gov/34411914Test


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  2. 2
    In vitro and in vivo inhibition of HCT116 cells by essential oils from bark and leaves of Virola surinamensis (Rol. ex Rottb.) Warb. (Myristicaceae)

    المؤلفون: Rafaela G.A. Costa, Milena Botelho Pereira Soares, Talita A. da Anunciação, Valdenizia R. Silva, Rosane Borges Dias, Daniel P. Bezerra, Emmanoel V. Costa, Clarissa Araújo Gurgel Rocha, Hector H. F. Koolen, Luciano de S. Santos, Emilly J. S. P. de Lima, Felipe M. A. da Silva

    المصدر: Journal of ethnopharmacology. 262

    مصطلحات موضوعية: Cell Survival, Virola surinamensis, Melanoma, Experimental, HL-60 Cells, Mice, SCID, Cell morphology, Myristicaceae, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, In vivo, Drug Discovery, Oils, Volatile, Animals, Humans, Propidium iodide, Fragmentation (cell biology), 030304 developmental biology, Pharmacology, 0303 health sciences, biology, Traditional medicine, Dose-Response Relationship, Drug, Hep G2 Cells, biology.organism_classification, HCT116 Cells, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Plant Leaves, chemistry, Apoptosis, 030220 oncology & carcinogenesis, Cancer cell, MCF-7 Cells, Plant Bark, Female

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3127a7de0de3b15022912e35ece00295Test
    https://pubmed.ncbi.nlm.nih.gov/32730868Test


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  3. 3
    Essential oil from leaves of Conobea scoparioides (Cham.Schltdl.) Benth. (Plantaginaceae) causes cell death in HepG2 cells and inhibits tumor development in a xenograft model

    المؤلفون: Clarissa Araújo Gurgel Rocha, Sheila Suarez Fontes, Felipe M. A. da Silva, Gigliola M.A. D’Elia, Hector H. F. Koolen, Emilly J. S. P. de Lima, Caroline Brandi Schlaepfer Sales, Mateus L. Nogueira, Marcos A. Vannier-Santos, Luciano de S. Santos, Rosane Borges Dias, Valdenizia R. Silva, Milena Botelho Pereira Soares, Emmanoel V. Costa, Daniel P. Bezerra

    المصدر: Biomedicine & Pharmacotherapy, Vol 129, Iss, Pp 110402-(2020)

    مصطلحات موضوعية: 0301 basic medicine, HepG2, Carcinoma, Hepatocellular, Apoptosis, RM1-950, Mice, SCID, law.invention, Conobea scoparioides, 03 medical and health sciences, 0302 clinical medicine, In vivo, law, Anti-liver cancer, Oils, Volatile, Cytotoxic T cell, Animals, Humans, Plant Oils, Essential oil, Pharmacology, Chemistry, Liver Neoplasms, Plantaginaceae, General Medicine, Hep G2 Cells, Cell cycle, HCT116 Cells, Molecular biology, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, In vitro, Tumor Burden, Plant Leaves, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, MCF-7 Cells, DNA fragmentation, Female, Therapeutics. Pharmacology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4b488b3eb44779f99d3d9c5d3ab49cTest
    https://pubmed.ncbi.nlm.nih.gov/32574969Test


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  4. 4
    Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives

    المؤلفون: Thiago D S Silva, Marcos Veríssimo de Oliveira Cardoso, Daniel P. Bezerra, Ana Cristina Lima Leite, Milena Botelho Pereira Soares, Larissa M. Bomfim, Caroline Brandi Schlaepfer Sales, Gardenia Carmen Gadelha Militão, Ana Carolina B. da C. Rodrigues, Clarissa Araújo Gurgel Rocha, Rosane Borges Dias

    المصدر: Repositório Institucional da UFBA
    Universidade Federal da Bahia (UFBA)
    instacron:UFBA

    مصطلحات موضوعية: Liver Cancer, HepG2, Cell Survival, Pyridines, Cytotoxicity, Antineoplastic Agents, Apoptosis, HL-60 Cells, Mice, SCID, Pharmacology, Biology, Toxicology, 01 natural sciences, Peripheral blood mononuclear cell, Inhibitory Concentration 50, Necrosis, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Animals, Humans, Cytotoxic T cell, Cell Proliferation, Toxicity, Dose-Response Relationship, Drug, 010405 organic chemistry, Liver Neoplasms, Cancer, Antitumor, Hep G2 Cells, medicine.disease, Xenograft Model Antitumor Assays, Tumor Burden, 0104 chemical sciences, Thiazoles, Drug Resistance, Neoplasm, Cell culture, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, MCF-7 Cells, Cancer research, Female, 2-Pyridyl 2,3-thiazoles, Liver cancer

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a67327f9c9f9c650cf31b1cd9038f1Test
    https://doi.org/10.1016/j.taap.2017.06.003Test


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  5. 5
    Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling

    المؤلفون: Suellen L. R. Silva, Clarissa Araújo Gurgel Rocha, Caroline Brandi Schlaepfer Sales, Alzir A. Batista, Rosane Borges Dias, Daniel P. Bezerra, Milena Botelho Pereira Soares, Ingrid R. S. Baliza, Rodrigo S. Corrêa

    المصدر: Repositório Institucional da UFOP
    Universidade Federal de Ouro Preto (UFOP)
    instacron:UFOP
    Scientific Reports
    Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

    مصطلحات موضوعية: 0301 basic medicine, Colon, MAP Kinase Signaling System, DNA damage, p38 mitogen-activated protein kinases, lcsh:Medicine, Apoptosis, Drug development, p38 Mitogen-Activated Protein Kinases, Ruthenium, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Humans, lcsh:Science, Cytotoxicity, Pharmacology, Multidisciplinary, biology, MEK inhibitor, lcsh:R, HCT116 Cells, Molecular biology, 030104 developmental biology, chemistry, Cell culture, Colonic Neoplasms, biology.protein, Mdm2, lcsh:Q, Tumor Suppressor Protein p53, Thymine, 030217 neurology & neurosurgery, DNA, DNA Damage, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea96f393e89514790cccb4ac39036eaeTest
    https://doi.org/10.1038/s41598-019-47539-0Test


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  6. 6
    Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathways in human acute promyelocytic leukemia cells

    المؤلفون: Rosane Borges Dias, Larissa M. Bomfim, Clarissa Araújo Gurgel Rocha, Daniel P. Bezerra, Milena Botelho Pereira Soares, Rodrigo S. Corrêa, Alzir A. Batista, Caroline Brandi Schlaepfer Sales, Fênix Alexandra de Araujo

    المصدر: Repositório Institucional da UFOP
    Universidade Federal de Ouro Preto (UFOP)
    instacron:UFOP
    Scientific Reports
    Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)

    مصطلحات موضوعية: 0301 basic medicine, Acute promyelocytic leukemia, MAP Kinase Signaling System, p38 mitogen-activated protein kinases, lcsh:Medicine, Apoptosis, HL-60 Cells, Ruthenium, Thiouracil, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Leukemia, Promyelocytic, Acute, Coordination Complexes, medicine, Animals, Humans, DNA Breaks, Double-Stranded, Phosphorylation, lcsh:Science, Cytotoxicity, Caspase, Cell Proliferation, Pharmacology, Haematological cancer, Multidisciplinary, biology, Chemistry, Cell growth, lcsh:R, Myeloid leukemia, medicine.disease, Xenograft Model Antitumor Assays, Molecular biology, 030104 developmental biology, Cell culture, Caspases, biology.protein, lcsh:Q, Female, 030217 neurology & neurosurgery

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88147edca357304bd30442bb2fdc5edcTest
    http://www.repositorio.ufop.br/handle/123456789/12372Test


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  7. 7
    Antitumour Activity of the Microencapsulation ofAnnona vepretorumEssential Oil

    المؤلفون: Rosane Borges Dias, Milena Botelho Pereira Soares, Albertino Freitas Santana Neto, Lidercia Cavalcanti Ribeiro Cerqueira E Silva, Emmanoel V. Costa, Magaly P. Nascimento, Clarissa Araújo Gurgel Rocha, Daniel P. Bezerra, Adriana Fernandes Campos, Ana Carolina B. da C. Rodrigues, Larissa M. Bomfim, Leociley R. A. Menezes

    المصدر: Basic & Clinical Pharmacology & Toxicology. 118:208-213

    مصطلحات موضوعية: Male, Melanoma, Experimental, Beta-Cyclodextrins, Toxicology, 01 natural sciences, Annona, law.invention, Terpene, Mice, Sesquiterpenes, Germacrane, chemistry.chemical_compound, law, Cytotoxicity, Bicyclic Monoterpenes, biology, Traditional medicine, beta-Cyclodextrins, Hep G2 Cells, General Medicine, Biochemistry, Annonaceae, Growth inhibition, Sesquiterpenes, Adult, Acyclic Monoterpenes, Drug Compounding, Cyclohexane Monoterpenes, Alkenes, Gas Chromatography-Mass Spectrometry, Inhibitory Concentration 50, Young Adult, In vivo, Cell Line, Tumor, Oils, Volatile, Animals, Humans, Essential oil, Pharmacology, Cyclohexanones, Terpenes, 010405 organic chemistry, biology.organism_classification, Antineoplastic Agents, Phytogenic, 0104 chemical sciences, Mice, Inbred C57BL, Plant Leaves, Disease Models, Animal, 010404 medicinal & biomolecular chemistry, chemistry, Monoterpenes

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b74629ab8633b6e7d90caf7622ae423Test
    https://doi.org/10.1111/bcpt.12488Test


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  8. 8
    In vitro and in vivo growth inhibition of human acute promyelocytic leukemia HL-60 cells by Guatteria megalophylla Diels (Annonaceae) leaf essential oil

    المؤلفون: Rafaela G.A. Costa, Cesar Augusto Silva de Souza, Rosane Borges Dias, Felipe M. A. da Silva, Hector H. F. Koolen, Talita A. da Anunciação, Morgana de Souza Araújo, Daniel P. Bezerra, Caroline Brandi Schlaepfer Sales, Milena Botelho Pereira Soares, Emmanoel V. Costa, Clarissa Araújo Gurgel Rocha

    المصدر: Biomedicine & Pharmacotherapy, Vol 122, Iss, Pp-(2020)

    مصطلحات موضوعية: Male, 0301 basic medicine, Acute promyelocytic leukemia, Guatteria, Annonaceae, HL-60 Cells, Mice, SCID, RM1-950, Biology, Essential oil, Cell Line, law.invention, Spathulenol, 03 medical and health sciences, chemistry.chemical_compound, Guatteria megalophylla, 0302 clinical medicine, Leukemia, Promyelocytic, Acute, law, In vivo, Cell Line, Tumor, Oils, Volatile, medicine, Animals, Humans, Cell Proliferation, Pharmacology, Traditional medicine, Hep G2 Cells, General Medicine, HCT116 Cells, biology.organism_classification, medicine.disease, Antineoplastic Agents, Phytogenic, In vitro, Plant Leaves, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, MCF-7 Cells, Plant Preparations, Therapeutics. Pharmacology, Growth inhibition, Anti-leukemia

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824a1743055f82193919b0cc8f7aecc9Test
    https://doi.org/10.1016/j.biopha.2019.109713Test


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  9. 9
    In vitro and in vivo anti-leukemia activity of the stem bark of Salacia impressifolia (Miers) A. C. Smith (Celastraceae)

    المؤلفون: Caroline Brandi Schlaepfer Sales, Rosane Borges Dias, Felipe P. de Oliveira, Ana Carolina B. da C. Rodrigues, Milena Botelho Pereira Soares, Felipe M. A. da Silva, Waldireny Caldas Rocha, Daniel P. Bezerra, Hector H. F. Koolen, Clarissa Araújo Gurgel Rocha, Emmanoel V. Costa

    المصدر: Journal of ethnopharmacology. 231

    مصطلحات موضوعية: Mice, SCID, Cell Line, Celastraceae, 03 medical and health sciences, 0302 clinical medicine, Salacia, In vivo, Drug Discovery, Cytotoxic T cell, Animals, Humans, Cytotoxicity, 030304 developmental biology, Pharmacology, 0303 health sciences, Leukemia, Traditional medicine, biology, Plant Stems, Chemistry, Plant Extracts, biology.organism_classification, Antineoplastic Agents, Phytogenic, In vitro, Cell culture, 030220 oncology & carcinogenesis, visual_art, Cancer cell, visual_art.visual_art_medium, Plant Bark, Bark, Female, Phytotherapy

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a571cc7768ab68da34e35f4e0fa3d4b1Test
    https://pubmed.ncbi.nlm.nih.gov/30445109Test


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  10. 10
    Antitumor Properties of the Leaf Essential Oil of Zornia brasiliensis

    المؤلفون: Emmanoel V. Costa, Leociley R. A. Menezes, Daniel P. Bezerra, Milena Botelho Pereira Soares, Ingrid R. S. Baliza, Suellen Laila Andrade Rocha, Clarissa Araújo Gurgel Rocha, Rosane Borges Dias

    المصدر: Planta Medica. 81:563-567

    مصطلحات موضوعية: Male, Farnesene, Melanoma, Experimental, Pharmaceutical Science, Biology, Analytical Chemistry, law.invention, Sesquiterpenes, Germacrane, chemistry.chemical_compound, law, In vivo, Drug Discovery, Botany, Oils, Volatile, Animals, Plant Oils, Cytotoxicity, Essential oil, Cell Proliferation, Polycyclic Sesquiterpenes, Pharmacology, Traditional medicine, Plant Extracts, Inoculation, Cell growth, Organic Chemistry, Fabaceae, Antineoplastic Agents, Phytogenic, Mice, Inbred C57BL, Monocyclic Sesquiterpenes, Plant Leaves, Complementary and alternative medicine, chemistry, Molecular Medicine, Phytotherapy, Sesquiterpenes

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29aa2b57f1ee411491550d91cf2dcfeTest
    https://doi.org/10.1055/s-0035-1545842Test


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