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1دورية أكاديمية
المؤلفون: Christopher G. Thomson, Kelly Boss, Amy Calhoun, Cary Fridrich, Kevin M. Gardinier, Edward C. Hall, Keith Jendza, Louise Kirman, Nancy Labbé-Giguere, Kurt Laumen, Ming Qian, Sanjit Sanyal, Michael D. Shultz, Radka Snajdrova, Kian Tan, Kate Yaping Wang, Fan Yang, Feng Gao, Tao Hong, Elena Dale, Brent Kuzmiski, Danny Ortuno, Daniel S. Palacios
مصطلحات موضوعية: Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Ecology, Sociology, Infectious Diseases, Chemical Sciences not elsewhere classified, synthetic sequence toward, early medicinal chemistry, chiral route toward, muscarinic m4 agonists, 10 b, m4 agonists, starting points, selective m1, bifunctional compounds, advanced intermediates
الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00331.s001Test
https://figshare.com/articles/journal_contribution/Transaminases_Provide_Key_Chiral_Building_Blocks_for_the_Synthesis_of_Selective_M1_M4_Agonists/24512113Test -
2
المؤلفون: J. Brent Kuzmiski, João M. Dias, Seungil Han, Chris Limberakis, David Price, David J. Edmonds, John M. Curto, Amit S. Kalgutkar, Daniel J. Lettiere, David A. Tess, Clare Buckeridge, Matthew C. Griffor, David R. Derksen, Alan M. Mathiowetz, Roger B. Ruggeri, Paula M. Loria, Aditi R. Saxena, Scott W. Bagley, Yuhang Liu, Margaret S. Landis, David W. Piotrowski, V. Margaret Jackson, David A. Griffith, Jean-Phillipe Fortin
مصطلحات موضوعية: chemistry.chemical_classification, Agonist, Chemistry, medicine.drug_class, Insulin, medicine.medical_treatment, Endogeny, Peptide, Pharmacology, Small molecule, Glucagon-like peptide-1, Oral administration, medicine, Receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::064b771366df377937229b83ffb7a9bfTest
https://doi.org/10.1101/2020.09.29.319483Test -
3
المؤلفون: Kiarash Riazi, Michael A. Galic, Winnie Ho, Keith A. Sharkey, J. Brent Kuzmiski, Quentin J. Pittman
المصدر: Proceedings of the National Academy of Sciences. 105:17151-17156
مصطلحات موضوعية: Central Nervous System, Male, medicine.medical_treatment, Central nervous system, Hippocampus, Inflammation, Pharmacology, Hippocampal formation, Biology, Rats, Sprague-Dawley, Seizures, medicine, Animals, Multidisciplinary, Microglia, Seizure threshold, Tumor Necrosis Factor-alpha, Biological Sciences, Colitis, Rats, medicine.anatomical_structure, Cytokine, Trinitrobenzenesulfonic Acid, Immunology, Cytokines, Tumor necrosis factor alpha, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40b08202e2b7bfb5b107689bc9fad70Test
https://doi.org/10.1073/pnas.0806682105Test -
4
المؤلفون: Bhavik P. Shah, Jean-Philippe Fortin, Alice Liou, A. Katrina Loomis, J. Brent Kuzmiski, Philip A. Carpino, V. Margaret Jackson, Marie-Laure Rives, Danna M. Breen
المصدر: Expert opinion on drug discovery. 10(8)
مصطلحات موضوعية: FGF21, Drug discovery, Critical pathways, Type 2 diabetes, Biology, Pharmacology, Bioinformatics, Body weight, medicine.disease, Obesity, Energy homeostasis, Weight loss, Drug Design, Drug Discovery, Weight Loss, medicine, Animals, Humans, Drug Therapy, Combination, Anti-Obesity Agents, Molecular Targeted Therapy, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90230c8b23637f9424f08e2482e8e43eTest
https://pubmed.ncbi.nlm.nih.gov/25967138Test