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المؤلفون: Amani Makkouk, Xue (Cher) Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman
المصدر: Journal for Immunotherapy of Cancer
مصطلحات موضوعية: Cancer Research, Carcinoma, Hepatocellular, T-Lymphocytes, Immunology, Apoptosis, Mice, SCID, cell engineering, adoptive, Immunotherapy, Adoptive, Mice, Glypicans, Mice, Inbred NOD, innate, Tumor Cells, Cultured, tumor microenvironment, Animals, Humans, Immunology and Allergy, Cell Proliferation, Interleukin-15, Pharmacology, Receptors, Chimeric Antigen, Immune Cell Therapies and Immune Cell Engineering, Liver Neoplasms, Receptors, Antigen, T-Cell, gamma-delta, immunity, Xenograft Model Antitumor Assays, Oncology, Leukocytes, Mononuclear, Molecular Medicine, Female, immunotherapy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e955ee28a80f5478bb3fb0c7d714e4Test
https://doi.org/10.1136/jitc-2021-003441Test -
2Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer
المؤلفون: Jennifer N. Rauch, Bryan M. Dunyak, Byron Hann, Peter Walter, Martin Kampmann, Megan Murnane, Min Cho, Xiaokai Li, Teresa A. Colvin, Jason E. Gestwicki, Diego Acosta-Alvear, Blake T. Aftab, Jonathan S. Weissman, Michael Y. Sherman
المصدر: Molecular cancer therapeutics, vol 14, iss 3
مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cancer Research, Oncology and Carcinogenesis, Allosteric regulation, Antineoplastic Agents, Pharmacology, BAG3, Article, Cell Line, Protein–protein interaction, Mice, Cell Line, Tumor, Proliferating Cell Nuclear Antigen, 2.1 Biological and endogenous factors, Animals, Humans, HSP70 Heat-Shock Proteins, Protein Interaction Domains and Motifs, Oncology & Carcinogenesis, Aetiology, Cancer, Adaptor Proteins, Signal Transducing, Cell Proliferation, Regulation of gene expression, Neoplastic, Tumor, biology, Effector, Forkhead Box Protein M1, Signal Transducing, Adaptor Proteins, Signal transducing adaptor protein, Forkhead Transcription Factors, Pharmacology and Pharmaceutical Sciences, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Oncology, Hela Cells, Chaperone (protein), MCF-7 Cells, Cancer research, biology.protein, FOXM1, Apoptosis Regulatory Proteins, HT29 Cells, HeLa Cells
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3b22505bee1d46a3729d48f13aa063Test
https://doi.org/10.1158/1535-7163.mct-14-0650Test -
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المؤلفون: Sandy W. Wong, Megan Murnane, Christine Lam, Hui Liu, Jun O. Liu, Jack Taunton, Arun P. Wiita, Byron Hann, Constantine S. Mitsiades, Blake T. Aftab, Geoffrey A. Smith
مصطلحات موضوعية: 0303 health sciences, Ruxolitinib, Tumor microenvironment, Stromal cell, Tofacitinib, business.industry, Mesenchymal stem cell, Pharmacology, 3. Good health, 03 medical and health sciences, Drug repositioning, 0302 clinical medicine, medicine.anatomical_structure, In vivo, 030220 oncology & carcinogenesis, medicine, Bone marrow, business, 030304 developmental biology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c78a14bc3f1504caee958397ee0259Test
https://doi.org/10.1101/143206Test -
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المؤلفون: Charles M. Rudin, Julie R. Brahmer, Jun O. Liu, David S. Ettinger, Ruth Smith, Peng Huang, Blake T. Aftab, Rosalyn A. Juergens, Christine L. Hann, Rosa Sebree
المصدر: Journal of Thoracic Oncology. 8(5):619-623
مصطلحات موضوعية: Male, Oncology, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Guanine, Lung Neoplasms, Itraconazole, medicine.medical_treatment, Phases of clinical research, Kaplan-Meier Estimate, Pemetrexed, Pharmacology, Disease-Free Survival, Article, 03 medical and health sciences, 0302 clinical medicine, Glutamates, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Lung cancer, Aged, 030304 developmental biology, Tube formation, 0303 health sciences, Chemotherapy, business.industry, Hazard ratio, Middle Aged, medicine.disease, 3. Good health, Clinical trial, 030220 oncology & carcinogenesis, Early Termination of Clinical Trials, Antiangiogenic, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acc2fbfc265f5566cd3165544f010aaTest
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المؤلفون: Philip A. Beachy, Alexandra Borodovsky, Daniel H. Kim, Baozhi Chen, Alexander Lee, Melika Rezaee, Ervin H. Epstein, James Kim, Jynho Kim, Gregory J. Riggins, Emily M. King, Charles M. Rudin, Blake T. Aftab, Jean Y. Tang
المصدر: Cancer Cell. 23(1):23-34
مصطلحات موضوعية: Cancer Research, Pyridines, Itraconazole, Antineoplastic Agents, Context (language use), Pharmacology, Biology, Arsenicals, Receptors, G-Protein-Coupled, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Arsenic Trioxide, GLI2, medicine, Animals, Anilides, Hedgehog Proteins, Arsenic trioxide, 030304 developmental biology, Medulloblastoma, 0303 health sciences, Oxides, Cell Biology, medicine.disease, Smoothened Receptor, Hedgehog signaling pathway, 3. Good health, chemistry, Oncology, Carcinoma, Basal Cell, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Smoothened, Signal Transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e7ef15dfa1007e4c08e307d327c7a5Test
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المؤلفون: Sanh Tan Lam, Edna F. Choo, Lillian Lee, Harvey Wong, Amy C. Peterson, Congfen Li, Yongchang Shi, Klaus P. Hoeflich, John Prescott, Geoffrey Del Rosario, Marcia Belvin, Jean-Francois Martini, Ron Aoyama, Peiwen Yu, Joeseph A Ware, Blake T. Aftab, Laurent Vernillet
المصدر: Clinical Cancer Research. 18:3090-3099
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Population, Mice, Nude, Antineoplastic Agents, Pharmacology, Models, Biological, Mice, Piperidines, Pharmacokinetics, In vivo, Cell Line, Tumor, Animals, Humans, Medicine, Potency, education, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, education.field_of_study, business.industry, MEK inhibitor, Melanoma, medicine.disease, Xenograft Model Antitumor Assays, Oncology, Pharmacodynamics, Azetidines, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afddce05a73ecd664670ea98a745ceb1Test
https://doi.org/10.1158/1078-0432.ccr-12-0445Test -
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المؤلفون: Blake T. Aftab, Charles M. Rudin
المصدر: Clinical Investigation. 2:371-385
مصطلحات موضوعية: Cyclopamine, business.industry, Cancer, General Medicine, Pharmacology, medicine.disease, Hedgehog signaling pathway, chemistry.chemical_compound, chemistry, Cancer stem cell, Cancer cell, medicine, Cancer research, Basal cell carcinoma, Clinical efficacy, business, Hedgehog
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ea11d09b91b0cd252e05cd9094324126Test
https://doi.org/10.4155/cli.12.20Test -
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المؤلفون: Charles M. Rudin, Jun O. Liu, Blake T. Aftab, Irina Dobromilskaya
المصدر: Cancer Research. 71:6764-6772
مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Bevacizumab, Angiogenesis, Itraconazole, Antifungal drug, Angiogenesis Inhibitors, Antineoplastic Agents, Mice, SCID, Adenocarcinoma, Pharmacology, Biology, Article, Neovascularization, Mice, Cell Movement, Mice, Inbred NOD, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Lung cancer, Cells, Cultured, Aged, Tube formation, Dose-Response Relationship, Drug, Neovascularization, Pathologic, Endothelial Cells, Cancer, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Xenograft Model Antitumor Assays, Oncology, Carcinoma, Squamous Cell, Intercellular Signaling Peptides and Proteins, Cisplatin, Drug Screening Assays, Antitumor, medicine.symptom, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b030299e6434523fc10f0bbcf18a80Test
https://doi.org/10.1158/0008-5472.can-11-0691Test -
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المؤلفون: Megan Murnane, Geoffrey A. Smith, Arun P. Wiita, Christine Lam, Jack Taunton, Blake T. Aftab
المصدر: Blood. 128:2098-2098
مصطلحات موضوعية: Ruxolitinib, Tumor microenvironment, Tofacitinib, Stromal cell, business.industry, Cell growth, medicine.medical_treatment, Immunology, Context (language use), Cell Biology, Hematology, Pharmacology, Biochemistry, Carfilzomib, chemistry.chemical_compound, Cytokine, chemistry, medicine, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5867f920ac2a61bea5047e3aceb0b5ceTest
https://doi.org/10.1182/blood.v128.22.2098.2098Test -
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المؤلفون: Eugen Dhimolea, Jeffrey L. Wolf, Pamela N. Munster, Blake T. Aftab, Jun O. Liu, Constantine S. Mitsiades, Aaron C Logan, Ruojing Li, Rosemary J. Akhurst, Arun P. Wiita, Megan Murnane, Diamond Wheeler, Megan Bariteau, Thomas G. Martin
المصدر: Blood. 126:503-503
مصطلحات موضوعية: Drug, Tofacitinib, Stromal cell, Bortezomib, business.industry, media_common.quotation_subject, Immunology, Cell Biology, Hematology, Synthetic lethality, Pharmacology, Biochemistry, Carfilzomib, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, medicine, Bone marrow, Janus kinase, business, medicine.drug, media_common
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0bdfc01d7b43f027eae2d50c81b353c9Test
https://doi.org/10.1182/blood.v126.23.503.503Test