نتائج البحث - "Voltage-gated ion channel"

1

A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome

المؤلفون: Glenn F. King, Volker Herzig, Joel Castro, Tianjiao Zhao, Sonia Garcia-Caraballo, Fernanda C. Cardoso, Richard J. Lewis, Luke Grundy, Gudrun Schober, Stuart M. Brierley

المصدر: Pain. 162:569-581

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::fa25e64859ec0a5963989b087d58fb4eTest
https://doi.org/10.1097/j.pain.0000000000002041Test

2

Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels

المؤلفون: Tamer M. Gamal El-Din, Michael J. Lenaeus, William A. Catterall

المصدر: Annual Review of Pharmacology and Toxicology. 60:133-154

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c792cead06498692a1a33d25e06e91dcTest
https://doi.org/10.1146/annurev-pharmtox-010818-021757Test

3

Triumeq Increases Excitability of Pyramidal Neurons in the Medial Prefrontal Cortex by Facilitating Voltage-Gated Ca2+ Channel Function

المؤلفون: Lihua Chen, Lena Al-Harthi, Xiu-Ti Hu

المصدر: Frontiers in Pharmacology, Vol 11 (2021)
Frontiers in Pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06efa7b4b36db6375e54930fee5ccf44Test
https://www.frontiersin.org/articles/10.3389/fphar.2020.617149/fullTest

4

1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain

المؤلفون: E. M. Kithsiri Wijeratne, Shreya S. Bellampalli, A. A. Leslie Gunatilaka, Song Cai, Yuan Zhou, Yingshi Ji, Kimberly Gomez, Shizhen Luo, Aubin Moutal, Rajesh Khanna

المصدر: Molecular Brain, Vol 13, Iss 1, Pp 1-12 (2020)
Molecular Brain

مصطلحات موضوعية: Limonins, 0301 basic medicine, 1-O-acetylgeopyxin a, Non-opioid pain-relieving therapeutics, Population, Action Potentials, HIV Infections, Tetrodotoxin, Pharmacology, Sodium Channels, lcsh:RC346-429, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Ganglia, Spinal, Animals, Voltage-gated calcium channels, Medicine, education, Tetrodotoxin-sensitive voltage-gated sodium channels, Molecular Biology, lcsh:Neurology. Diseases of the nervous system, HIV-induced sensory neuropathy, education.field_of_study, Excitability, Voltage-gated ion channel, Voltage-dependent calcium channel, business.industry, Research, Sodium channel, Chronic pain, Nociceptors, Calcium Channel Blockers, medicine.disease, Rats, 030104 developmental biology, Rheobase, Pharmaceutical Preparations, Hyperalgesia, Neuropathic pain, Nociceptor, Neuralgia, Female, Calcium Channels, Voltage-gated sodium channels, business, 030217 neurology & neurosurgery, Sodium Channel Blockers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574e3e3829fc5f6f4cd5d51887e1bcc0Test
https://doi.org/10.1186/s13041-020-00616-2Test

5

Structural Basis for Diltiazem Block of a Voltage-Gated Ca(2+) Channel

المؤلفون: Lin Tang, Ning Zheng, Tamer M. Gamal El-Din, Michael J. Lenaeus, William A. Catterall

المصدر: Mol Pharmacol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab9d526bfbee4b60321b8d22915fa88Test
https://europepmc.org/articles/PMC6738535Test/

6

Involvement of the PKA pathway and inhibition of voltage gated Ca2+ channels in antihyperalgesic activity of Lippia grata/β-cyclodextrin

المؤلفون: Horácio Freitas Bomfim, Aline S. Medrado, José Evaldo Rodrigues de Menezes-Filho, Angélica Maria Lucchese, Erik Willyame Menezes Pereira, Pollyana S. Siqueira-Lima, Luana Heimfarth, Fabiolla Rocha Santos Passos, Henrique Douglas Melo Coutinho, Rosana S.S. Barreto, Sathiyabama R. Gandhi, Jullyana S.S. Quintans, Marilia M. Rezende, Adriano Antunes de Souza Araújo, Lucindo José Quintans-Júnior, Lígia Araujo Naves

المصدر: Life sciences. 239

مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, Nociception, Pain Threshold, medicine.drug_class, Pain, Pharmacology, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Dorsal root ganglion, Ganglia, Spinal, Threshold of pain, medicine, Oils, Volatile, Animals, General Pharmacology, Toxicology and Pharmaceutics, Rats, Wistar, Pain Measurement, Voltage-gated ion channel, Voltage-dependent calcium channel, Chemistry, Plant Extracts, beta-Cyclodextrins, Chronic pain, General Medicine, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Hyperalgesia, Neuropathic pain, Neuralgia, Chronic Pain, Lippia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef150b1029b2db1382d294442a17267Test
https://pubmed.ncbi.nlm.nih.gov/31654745Test

7

Voltage gated sodium channels and epilepsy

المؤلفون: Simon Hebeisen

المصدر: Journal of Cellular Neuroscience and Oxidative Stress
Volume: 10, Issue: 3 780-780

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35334d86cc0981224ba92d017508dd8dTest
https://dergipark.org.tr/tr/pub/jcnos/issue/46413/584668Test

8

The Venom of the Spider Selenocosmia Jiafu Contains Various Neurotoxins Acting on Voltage-Gated Ion Channels in Rat Dorsal Root Ganglion Neurons

المؤلفون: Zhonghua Liu, Xi Zhou, Dazhong Ying, Cheng Tang, Jia Chen, Zhen Xiao, Songping Liang, Zhaotun Hu

المصدر: Toxins; Volume 6; Issue 3; Pages: 988-1001
Toxins, Vol 6, Iss 3, Pp 988-1001 (2014)
Toxins

مصطلحات موضوعية: Male, Health, Toxicology and Mutagenesis, Spider Venoms, lcsh:Medicine, Cockroaches, Peptide, Venom, Voltage-Gated Sodium Channels, Pharmacology, Toxicology, Rats, Sprague-Dawley, Mice, Dorsal root ganglion, Ganglia, Spinal, DRG neuron, Chromatography, High Pressure Liquid, Neurons, chemistry.chemical_classification, Voltage-dependent calcium channel, biology, Spiders, Selenocosmia jiafu, spider venom, RP-HPLC, MALDI-TOF-MS, patch clamp analysis, voltage-gated ion channel, Anatomy, Calcium Channel Blockers, medicine.anatomical_structure, Potassium Channels, Voltage-Gated, Selenocosmia, Female, Sodium Channel Blockers, Neurotoxins, complex mixtures, Article, Lethal Dose 50, medicine, Animals, Patch clamp, Voltage-gated ion channel, Sodium channel, lcsh:R, biology.organism_classification, Rats, chemistry, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Calcium Channels, Peptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a20576ee276dd5541d2144be501f713Test
https://doi.org/10.3390/toxins6030988Test

9

Voltage-Gated R-Type Calcium Channel Inhibition via Humanμ-,δ-, andκ-opioid Receptors Is Voltage-Independently Mediated by GβγProtein Subunits

المؤلفون: David J. Adams, Géza Berecki, Leonid Motin

المصدر: Molecular Pharmacology. 89:187-196

مصطلحات موضوعية: 0301 basic medicine, Enkephalin, G protein, medicine.drug_class, Receptors, Opioid, mu, Guanosine, Calcium Channels, R-Type, Pharmacology, Pertussis toxin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Opioid receptor, GTP-Binding Protein gamma Subunits, Receptors, Opioid, delta, medicine, Humans, Voltage-gated ion channel, Voltage-dependent calcium channel, Receptors, Opioid, kappa, GTP-Binding Protein beta Subunits, Enkephalin, Ala(2)-MePhe(4)-Gly(5), Calcium Channel Blockers, Analgesics, Opioid, R-type calcium channel, Protein Subunits, HEK293 Cells, 030104 developmental biology, chemistry, Biophysics, Molecular Medicine, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5141c585d2a42e4b1f4de581f5b5caaTest
https://doi.org/10.1124/mol.115.101154Test

10

Structural Basis for Pharmacology of Voltage-Gated Sodium and Calcium Channels

المؤلفون: William A. Catterall, T.M. Swanson

المصدر: Molecular Pharmacology. 88:141-150

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b059dbc9a4aaf82dab0d6b3769057aTest
https://doi.org/10.1124/mol.114.097659Test

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