المؤلفون: Rommel G. Tirona, Bradley L. Urquhart, Marianne K. DeGorter, Richard B. Kim, U. Gradhand

المصدر: The Journal of Clinical Pharmacology. 52:1689-1697

مصطلحات موضوعية: Adult, Male, Simvastatin, Statin, medicine.drug_class, Atorvastatin, Context (language use), Organic Anion Transporters, Sodium-Independent, Pharmacology, Mice, Young Adult, Pharmacokinetics, Animals, Humans, Medicine, Pyrroles, Pharmacology (medical), Rosuvastatin, cardiovascular diseases, Rosuvastatin Calcium, Mice, Knockout, Sulfonamides, Cross-Over Studies, Liver-Specific Organic Anion Transporter 1, business.industry, nutritional and metabolic diseases, Middle Aged, Crossover study, Fluorobenzenes, Pyrimidines, Liver, Heptanoic Acids, Area Under Curve, Female, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a83a1f381dfdd882cd9743a10f6dc4Test
https://doi.org/10.1177/0091270011422815Test

المؤلفون: J J Yang, C Q Xia, Richard B. Kim, Marianne K. DeGorter

المصدر: Annual Review of Pharmacology and Toxicology. 52:249-273

مصطلحات موضوعية: Drug, Drug-Related Side Effects and Adverse Reactions, media_common.quotation_subject, Pharmacology, Biology, Toxicology, Food-Drug Interactions, Pharmacokinetics, In vivo, Animals, Humans, Drug Interactions, media_common, Polymorphism, Genetic, Biological Transport, Transporter, Diet, Solute carrier family, Pharmaceutical Preparations, Pharmacogenetics, Drug Design, Models, Animal, Toxicity, ATP-Binding Cassette Transporters, Multidrug Resistance-Associated Proteins, Carrier Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329fce55a071d7d5eb40a4abc1f256e2Test
https://doi.org/10.1146/annurev-pharmtox-010611-134529Test

المؤلفون: Otito Iwuchukwu, Robert A. Hegele, George K. Dresser, Rommel G. Tirona, Richard B. Kim, Marianne K. DeGorter, Kathryn Myers, Ute I. Schwarz, Russell A. Wilke, Guangyong Zou, Wei-Qi Wei, Yun-Hee Choi, Neville Suskin

المصدر: Paediatrics Publications

مصطلحات موضوعية: Male, Databases, Factual, Atorvastatin, Organic Anion Transporters, Pharmacology, Hydroxymethylglutaryl-CoA reductase inhibitors, Cohort Studies, Medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, Prospective Studies, Rosuvastatin Calcium, Genetics (clinical), Aged, 80 and over, Sulfonamides, biology, Liver-Specific Organic Anion Transporter 1, Middle Aged, Neoplasm Proteins, Cholesterol, Cohort, Organic anion transporters, Female, Cardiology and Cardiovascular Medicine, medicine.drug, Adult, medicine.medical_specialty, Statin, Genotype, medicine.drug_class, Hypercholesterolemia, Sodium-independent, Polymorphism, Single Nucleotide, Article, Internal medicine, Genetics, Humans, Pharmacokinetics, Rosuvastatin, Pyrroles, Dosing, Alleles, Aged, Retrospective Studies, Polymorphism, Genetic, business.industry, ATP-binding cassette transporters, Hydroxycholesterols, Fluorobenzenes, Pyrimidines, Pharmacogenetics, Heptanoic Acids, biology.protein, Linear Models, ATP-Binding Cassette Transporters, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, SLCO1B1, Body mass index

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a470beb1834b771e54d34bf878df3aaTest
https://pubmed.ncbi.nlm.nih.gov/23876492Test

المؤلفون: Sarah Woolsey, George K. Dresser, Natalie Crown, Rommel G. Tirona, Colin M. Suen, Michael J. Knauer, Inna Y. Gong, Marianne K. DeGorter, Ute I. Schwarz, Richard B. Kim, Daisuke Sugiyama

المصدر: Paediatrics Publications

مصطلحات موضوعية: Adult, Ticlopidine, Adolescent, Platelet Aggregation, Metabolite, Midazolam, CYP2C19, Pharmacology, chemistry.chemical_compound, Young Adult, Pharmacokinetics, In vivo, Medicine, Cytochrome P-450 CYP3A, Humans, cardiovascular diseases, Enzyme Inhibitors, PON1, Active metabolite, Biotransformation, Polymorphism, Genetic, business.industry, Aryldialkylphosphatase, Antiplatelet response, Middle Aged, Clopidogrel, Cytochrome P-450 CYP2C19, chemistry, Pharmacogenetics, Anesthesia, Area Under Curve, Aryl Hydrocarbon Hydroxylases, Cardiology and Cardiovascular Medicine, business, Platelet Aggregation Inhibitors, circulatory and respiratory physiology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a2f8f666f673939138dd05ededf455Test
https://pubmed.ncbi.nlm.nih.gov/22374717Test