المؤلفون: Yee, Sook Wah, Brackman, Deanna J, Ennis, Elizabeth A, Sugiyama, Yuichi, Kamdem, Landry K, Blanchard, Rebecca, Galetin, Aleksandra, Zhang, Lei, Giacomini, Kathleen M

المصدر: Clinical Pharmacology & Therapeutics. 104(5)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Drug Abuse (NIDA only), Genetics, Patient Safety, Clinical Research, Substance Misuse, Good Health and Well Being, Animals, Drug Interactions, Drug-Related Side Effects and Adverse Reactions, Genotype, Humans, Membrane Transport Proteins, Pharmaceutical Preparations, Pharmacogenomic Variants, Pharmacokinetics, Phenotype, Polymorphism, Genetic, Risk Assessment, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/39j1d4xhTest

المؤلفون: Zamek‐Gliszczynski, Maciej J, Taub, Mitchell E, Chothe, Paresh P, Chu, Xiaoyan, Giacomini, Kathleen M, Kim, Richard B, Ray, Adrian S, Stocker, Sophie L, Unadkat, Jashvant D, Wittwer, Matthias B, Xia, Cindy, Yee, Sook‐Wah, Zhang, Lei, Zhang, Yan, Consortium, International Transporter

المصدر: Clinical Pharmacology & Therapeutics. 104(5)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Digestive Diseases, Patient Safety, Liver Disease, Animals, Drug Development, Drug Interactions, Humans, Membrane Transport Modulators, Membrane Transport Proteins, Models, Biological, Pharmaceutical Preparations, Pharmacokinetics, Risk Assessment, International Transporter Consortium, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9vt2v0jjTest

المؤلفون: Cooper-DeHoff, Rhonda M., Niemi, Mikko, Ramsey, Laura B., Luzum, Jasmine A., Tarkiainen, E. Katriina, Straka, Robert J., Gong, Li, Tuteja, Sony, Wilke, Russell A., Wadelius, Mia, Larson, Eric A., Roden, Dan M., Klein, Teri E., Yee, Sook Wah, Krauss, Ronald M., Turner, Richard M., Palaniappan, Latha, Gaedigk, Andrea, Giacomini, Kathleen M., Caudle, Kelly E., Voora, Deepak

المساهمون: HUSLAB, Department of Clinical Pharmacology, Medicum, Department of Diagnostics and Therapeutics, INDIVIDRUG - Individualized Drug Therapy, HUS Diagnostic Center

مصطلحات موضوعية: INDUCED MYOPATHY, PHARMACOKINETICS, RISK, RHABDOMYOLYSIS, VARIANTS, ALLELES, IMPACT, 3111 Biomedicine, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: This work was funded by the National Institutes of Health (NIH) for CPIC (R24GM115264 and U24HG010135) and The Pharmacogenomics Knowledgebase (PharmGKB) (U24 HG010615). Additional author support includes P50GM115318 (R.M.K.), HL143161 (S.T.), U01HG007269 (R.M.C.-D.), R01GM117163 (K.M.G., S.W.Y.), and K08HL146990 (J.A.L.). M.N. is funded by a European Research Council ERC Consolidator Grant (Grant agreement 725249).; Cooper-DeHoff , R M , Niemi , M , Ramsey , L B , Luzum , J A , Tarkiainen , E K , Straka , R J , Gong , L , Tuteja , S , Wilke , R A , Wadelius , M , Larson , E A , Roden , D M , Klein , T E , Yee , S W , Krauss , R M , Turner , R M , Palaniappan , L , Gaedigk , A , Giacomini , K M , Caudle , K E & Voora , D 2022 , ' The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms ' , Clinical Pharmacology and Therapeutics , vol. 111 , no. 5 , pp. 1007-1021 . https://doi.org/10.1002/cpt.2557Test; fadcd828-cb4e-452b-b670-e21c36bdded6; http://hdl.handle.net/10138/357530Test; 000767481000001

الإتاحة: http://hdl.handle.net/10138/357530Test

المؤلفون: Yee, Sook Wah, Nguyen, Anh Nguyet, Brown, Chaline, Savic, Radojka M, Zhang, Youcai, Castro, Richard A, Cropp, Cheryl D, Choi, Ji Ha, Singh, Diment, Tahara, Harunobu, Stocker, Sophie L, Huang, Yong, Brett, Claire M, Giacomini, Kathleen M

المصدر: Journal of Pharmaceutical Sciences. 102(9)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Research, Kidney Disease, Adolescent, Adult, Anti-Bacterial Agents, Asian People, Cefotaxime, Female, Gene Frequency, HEK293 Cells, Humans, Kidney, Male, Organic Anion Transporters, Sodium-Independent, Polymorphism, Genetic, Young Adult, organic anion transporter, cefotaxime, tubular secretion, OAT3, polymorphisms, pharmacogenomic, pharmacokinetics, renal clearance, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/98f5f0thTest

المؤلفون: Morrissey, Kari M, Stocker, Sophie L, Wittwer, Matthias B, Xu, Lu, Giacomini, Kathleen M

المصدر: The Annual Review of Pharmacology and Toxicology. 53(1)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Kidney Disease, Patient Safety, Genetics, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Renal and urogenital, Animals, Biological Transport, Humans, Inactivation, Metabolic, Kidney Tubules, Pharmaceutical Preparations, Pharmacokinetics, Xenobiotics, renal clearance, SLC transporters, ABC transporters, drug metabolism, nephrotoxicity, pharmacokinetics, Biological Sciences, Medical and Health Sciences, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/189450bfTest

المؤلفون: Li, Shuanglian, Chen, Ying, Zhang, Shuzhong, More, Swati S, Huang, Xiaozhu, Giacomini, Kathleen M

المصدر: Pharmaceutical Research. 28(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Digestive Diseases, Liver Disease, Animals, Cells, Cultured, HEK293 Cells, Humans, Kidney, Male, Mice, Mice, Knockout, Organic Cation Transporter 1, Organoplatinum Compounds, Oxaliplatin, Tissue Distribution, OCT I, pharmacokinetics, platinum agent, toxicity, transporter, Pharmacology and Pharmaceutical Sciences, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/47h1n2mfTest

المؤلفون: Giacomini, Kathleen M., Huang, Shiew Mei

المصدر: Clinical Pharmacology & Therapeutics; Sep2022, Vol. 112 Issue 3, p423-426, 4p

مصطلحات موضوعية: CLINICAL pharmacology, PHARMACOKINETICS, ORGANIC anion transporters, SMALL molecules, ATP-binding cassette transporters

المؤلفون: Zamek-Gliszczynski, Maciej J, Taub, Mitchell E, Chothe, Paresh P, Chu, Xiaoyan, Giacomini, Kathleen M, Kim, Richard B, Ray, Adrian S, Stocker, Sophie L, Unadkat, Jashvant D, Wittwer, Matthias B, Xia, Cindy, Yee, Sook-Wah, Zhang, Lei, Zhang, Yan, International Transporter Consortium

المصدر: Clinical pharmacology and therapeutics, vol 104, iss 5

مصطلحات موضوعية: Liver Disease, Membrane Transport Proteins, Pharmacology and Pharmaceutical Sciences, Biological, Risk Assessment, International Transporter Consortium, Pharmaceutical Preparations, Drug Development, Models, Membrane Transport Modulators, Animals, Humans, Pharmacokinetics, Drug Interactions, Patient Safety, Pharmacology & Pharmacy, Digestive Diseases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od_______325::8f64540982f7db8f540f5c88effdffd7Test
https://escholarship.org/uc/item/9vt2v0jjTest

المؤلفون: Zamek-Gliszczynski, Maciej J., Taub, Mitchell E., Chothe, Paresh P., Chu, Xiaoyan, Giacomini, Kathleen M., Kim, Richard B., Ray, Adrian S., Stocker, Sophie L., Bingham, Jashvant D., Wang, Zhuozhi, Pellecchia, Giovanna, Buchanan, Janet A., Walker, Susan, Marshall, Christian R., Uddin, Mohammed, Zarrei, Mehdi, Deneault, Eric, D'Abate, Lia, Chan, Ada J.S., Koyanagi, Stephanie, Paton, Tara, Pereira, Sergio L., Hoang, Ny, Engchuan, Worrawat, Higginbotham, Edward J., Ho, Karen

المصدر: Clin Pharmacol Ther
Paediatrics Publications

مصطلحات موضوعية: 0301 basic medicine, Organ function, Pharmacology, 030226 pharmacology & pharmacy, Models, Biological, Risk Assessment, Prospective evaluation, Article, 03 medical and health sciences, 0302 clinical medicine, Vitamin deficiency, Drug Development, Membrane Transport Modulators, medicine, Animals, Humans, Pharmacology (medical), Drug Interactions, Pharmacokinetics, Organic cation transport proteins, biology, business.industry, Membrane Transport Proteins, Transporter, medicine.disease, Organic anion-transporting polypeptide, 030104 developmental biology, Drug development, Pharmaceutical Preparations, biology.protein, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fd51b02e8224423ba8b95917986c3cTest
https://europepmc.org/articles/PMC8211378Test/

المؤلفون: Vora, Bianca, Brackman, Deanna J., Zou, Ling, Garcia‐Cremades, Maria, Sirota, Marina, Savic, Radojka M., Giacomini, Kathleen M.

المصدر: CTS: Clinical & Translational Science; Jul2021, Vol. 14 Issue 4, p1431-1443, 13p

مصطلحات موضوعية: PHARMACODYNAMICS, PHARMACOKINETICS, BREAST cancer, ELECTRONIC health records, URIC acid