نتائج البحث - "Fujita, Ken-Ichi"

1

دورية أكاديمية

A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer.

المؤلفون: Shibata, Yukitaka, Matsumoto, Natsumi, Murase, Remi, Kubota, Yutaro, Ishida, Hiroo, Shimada, Ken, Fujita, Ken-ichi

المصدر: Cancer Chemotherapy & Pharmacology; Dec2023, Vol. 92 Issue 6, p465-474, 10p

مصطلحات موضوعية: JAPANESE people, COLORECTAL cancer, CANCER patients, HIGH performance liquid chromatography, ATP-binding cassette transporters

2

دورية أكاديمية

Pharmacokinetics of gefitinib in elderly patients with EGFR-mutated advanced non-small cell lung cancer: a prospective study.

المؤلفون: Nio, Yuta, Ishida, Hiroo, Matsumoto, Natsumi, Kusumoto, Sojiro, Kubota, Yutaro, Tsunoda, Takuya, Sasaki, Yasutsuna, Fujita, Ken-ichi

المصدر: BMC Pulmonary Medicine; 12/1/2022, Vol. 22 Issue 1, p1-9, 9p

النص الكامل

3

دورية أكاديمية

Minimal contribution of the hepatic uptake transporter OATP1B1 to the inter-individual variability in SN-38 pharmacokinetics in cancer patients without severe renal failure.

المؤلفون: Tsuboya, Ayako, Kubota, Yutaro, Ishida, Hiroo, Ohkuma, Ryotaro, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsunoda, Takuya, Sasaki, Yasutsuna, Matsumoto, Natsumi, Kondo, Yusuke, Tomoda, Yukana, Kusuhara, Hiroyuki, Fujita, Ken-ichi

المصدر: Cancer Chemotherapy & Pharmacology; Sep2021, Vol. 88 Issue 3, p543-553, 11p

مصطلحات موضوعية: KIDNEY failure, TANDEM mass spectrometry, CANCER patients, HIGH performance liquid chromatography, PHARMACOKINETICS

4

دورية أكاديمية

Variants of carboxylesterase 1 have no impact on capecitabine pharmacokinetics and toxicity in capecitabine plus oxaliplatin treated-colorectal cancer patients.

المؤلفون: Matsumoto, Natsumi, Kubota, Yutaro, Ishida, Hiroo, Sekido, Masae, Ohkuma, Ryotaro, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsunoda, Takuya, Ikusue, Toshikazu, Kobayashi, Kouji, Hisamatsu, Atsushi, Toshima, Hirokazu, Shimada, Ken, Fujita, Ken-ichi

المصدر: Cancer Chemotherapy & Pharmacology; Jun2020, Vol. 85 Issue 6, p1119-1128, 10p

مصطلحات موضوعية: ANTIMETABOLITES, PHARMACOKINETICS, CANCER patients, HIGH performance liquid chromatography, COLORECTAL cancer, CARBOXYLESTERASES

5

دورية أكاديمية

Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, and 5-fluorouracil.

المؤلفون: Sekido, Masae¹ (AUTHOR), Fujita, Ken-ichi¹ (AUTHOR) k.fujita@med.showa-u.ac.jp, Kubota, Yutaro² (AUTHOR), Ishida, Hiroo² (AUTHOR), Takahashi, Takehiro² (AUTHOR), Ohkuma, Ryotaro² (AUTHOR), Tsunoda, Takuya² (AUTHOR), Ishikawa, Fumihiro¹ (AUTHOR), Shibanuma, Motoko¹ (AUTHOR), Sasaki, Yasutsuna² (AUTHOR)

المصدر: Cancer Chemotherapy & Pharmacology. Jun2019, Vol. 83 Issue 6, p1127-1135. 9p.

مصطلحات موضوعية: *ANTIMETABOLITES, *HYPOMAGNESEMIA, *METABOLITES, *PROTON pump inhibitors, *COLON cancer, *THERAPEUTICS, *CANCER cells

6

دورية أكاديمية

Pazopanib interacts with irinotecan by inhibiting UGT1A1-mediated glucuronidation, but not OATP1B1-mediated hepatic uptake, of an active metabolite SN-38.

المؤلفون: Iwase, Mariko¹ (AUTHOR), Fujita, Ken-ichi^2,3 (AUTHOR) k.fujita@med.showa-u.ac.jp, Nishimura, Yuki¹ (AUTHOR), Seba, Natsumi⁴ (AUTHOR), Masuo, Yusuke⁴ (AUTHOR), Ishida, Hiroo⁵ (AUTHOR), Kato, Yukio⁴ (AUTHOR), Kiuchi, Yuji¹ (AUTHOR)

المصدر: Cancer Chemotherapy & Pharmacology. May2019, Vol. 83 Issue 5, p993-998. 6p.

مصطلحات موضوعية: *MICROSOMES, *GLUCURONIDATION, *PROTEIN-tyrosine kinases, *LIVER microsomes, *KINASE inhibitors

7

دورية أكاديمية

Association of pharmacokinetics and pharmacogenomics with safety and efficacy of gefitinib in patients with EGFR mutation positive advanced non-small cell lung cancer.

المؤلفون: Hirose, Takashi^1,2 thirose-shw@umin.ac.jp, Fujita, Ken-ichi³, Kusumoto, Sojiro², Oki, Yasunari², Murata, Yasunori², Sugiyama, Tomohide², Ishida, Hiroo⁴, Shirai, Takao², Nakashima, Masanao², Yamaoka, Toshimitsu³, Okuda, Kentaro², Ohmori, Tohru³, Sasaki, Yasutsuna⁴

المصدر: Lung Cancer (01695002). Mar2016, Vol. 93, p69-76. 8p.

مصطلحات موضوعية: *PHARMACOKINETICS, *PHARMACOGENOMICS, *GEFITINIB, *EPIDERMAL growth factor receptors, *PROTEIN-tyrosine kinase inhibitors, *PROGRESSION-free survival, *INTERSTITIAL lung diseases, *THERAPEUTICS

8

دورية أكاديمية

Increased Plasma Concentrations of Unbound SN-38, the Active Metabolite of Irinotecan, in Cancer Patients with Severe Renal Failure.

المؤلفون: Fujita, Ken-ichi k.fujita@med.showa-u.ac.jp, Masuo, Yusuke¹, Okumura, Hidenori¹, Watanabe, Yusuke², Suzuki, Hiromichi², Sunakawa, Yu, Shimada, Ken, Kawara, Kaori³, Akiyama, Yuko³, Kitamura, Masanori⁴, Kunishima, Munetaka⁴, Sasaki, Yasutsuna, Kato, Yukio¹ ykato@p.kanazawa-u.ac.jp

المصدر: Pharmaceutical Research. Feb2016, Vol. 33 Issue 2, p269-282. 14p. 2 Diagrams, 2 Charts, 6 Graphs.

مصطلحات موضوعية: *RENAL cancer treatment, *KIDNEY failure, *BLOOD plasma, *IRINOTECAN, *PHARMACOKINETICS, *KIDNEY physiology

9

دورية أكاديمية

A clinical pharmacokinetic microdosing study of docetaxel with Japanese patients with cancer.

المؤلفون: Fujita, Ken-ichi k.fujita@med.showa-u.ac.jp, Yoshino, Etsuko¹, Kawara, Kaori², Maeda, Kazuya³, Kusuhara, Hiroyuki³, Sugiyama, Yuichi, Yokoyama, Taro², Kaneta, Toshikado, Ishida, Hiroo, Sasaki, Yasutsuna

المصدر: Cancer Chemotherapy & Pharmacology. Oct2015, Vol. 76 Issue 4, p793-801. 9p.

مصطلحات موضوعية: *PHARMACOKINETICS, *MICRODOSIMETRY, *DOCETAXEL, *JAPANESE people, *CANCER patients, *CANCER treatment, *DISEASES

10

دورية أكاديمية

No pharmacokinetic alteration of docetaxel following coadministration of aprepitant 3 h before docetaxel infusion.

المؤلفون: Kaneta, Toshikado, Fujita, Ken-ichi k.fujita@med.showa-u.ac.jp, Akiyama, Yuko, Kawara, Kaori¹, Sunakawa, Yu, Kawachi, Asuka¹, Shimada, Ken, Sasaki, Yasutsuna

المصدر: Cancer Chemotherapy & Pharmacology. Sep2014, Vol. 74 Issue 3, p539-547. 9p.

مصطلحات موضوعية: *DOCETAXEL, *DRUG administration, *COMBINATION drug therapy, *CANCER treatment, *CANCER patients, *CROSSOVER trials, *DRUG interactions, *PHARMACOKINETICS

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