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    المصدر: Biotechnology in the Agricultural and Agroindustrial Sector; Vol. 19 No. 1 (2021): January to June; 105-116 ; Biotecnología en el Sector Agropecuario y Agroindustrial; Vol. 19 Núm. 1 (2021): Enero a Junio; 105-116 ; 1909-9959 ; 1692-3561

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    العلاقة: https://revistas.unicauca.edu.co/index.php/biotecnologia/article/view/1468/1425Test; GUZMAN, Y.E.; NAVARRO C.A.; ROA, M.L. Efecto del uso de probióticos en la morfometría intestinal de pollos de engorde. Archivos De Zootecnia, v.67, n. 257, 2018, p. 93–98. https://doi.org/10.21071/az.v0i0.3878Test; FENELON, MARK; HAYES, MARIA; HENCHION, MAEVE; MULLEN, ANNE-MARIA; TIWARI, BRIJESH. Future protein supply and demand: strategies and factors Influencing a sustainable equilibrium. Foods, v. 6, n. 7, 2017, p. 1-21. 10.3390/foods6070053; SOKALE, A.O.; MENCONI, A.; MATHIS, G.F.; LUMPKINS, B.; SIMS, M.D.; WHELAN, R.A.; DORANALLI, K. Effect of Bacillus subtilis DSM 32315 on the intestinal structural integrity and growth performance of broiler chickens under necrotic enteritis challenge. Poultry Science, v. 98, n. 11, 2019, p. 5392–5400. https://doi.org/10.3382/ps/pez368Test; KROCKO, MIROSLAV; CANIGOVÁ, MARGITA; BEZEKOVA, JANA; LAVOVÁ, MONIKA; HASCÍK, PETER; DUCKOVÁ, VIERA. Effect of nutrition with propolis and bee pollen supplements on bacteria colonization pattern in gastrointestinal tract of broiler chickens. Scientific Papers Animal Science and Biotechnologies, v. 45, n. 1, 2012, p. 63–67.; KIM, IN-HO; MOHAMMADIGHEISAR, MOHSEN. Phytobiotics in poultry and swine nutrition - a review. Italian Journal Of Animal Science, v. 17, n. 1, 2018, p. 92-99. 10.1080/1828051X.2017.1350120; REIS, M.P.; FASSANI, E.J.; GARCIA-JÚNIOR, A.A.P.; RODRIGUES, P.B.; BERTECHINI, A.G.; BARRET, N.; PERSIA, M.E.; SCHMIDT, C.J. Effect of Bacillus subtilis (DSM 17299) on performance, digestibility, intestine morphology, and pH in broiler chickens. Journal Of Applied Poultry Research, v. 26, n. 4, 2017, p. 573–583. https://doi.org/10.3382/japr/pfx032Test; SUGIHARTO, SUGIHARTO. Role of nutraceuticals in gut health and growth performance of poultry. Journal Of The Saudi Society Of Agricultural Sciences, v. 15, n. 2, 2016, p. 99–111. https://doi.org/10.1016/j.jssas.2014.06.001Test; MEHDI, YOUCEF; LÉTOURNEAU-MONTMINT, MARIE-PIERRE; GAUCHER, MARIE-LOU; CHORFI, YOUNES; SURESH, GAYATRI; ROUISSI, TAREK; KAUR-BRAR, SATINDER; COTÉ, CAROLINE; AVALOS-RAMIREZ, ANTONIO; GODBOUT, STÉPHANE. Use of antibiotics in broiler production: global impacts and alternatives. Animal Nutrition, v. 4, n. 2, 2018, p. 170–178. https://doi.org/10.1016/j.aninu.2018.03.002Test; SALIM, HOSSAN M.D.; SHAHIDUL-HUQUE, KHAN; KAMARUDDIN, KAZI M.; HAQUE-BEG, ANWARUL. Global restriction of using antibiotic growth promoters and alternative strategies in poultry production. Science Progress, v. 101, n. 1, 2018, p. 52–75. 10.3184/003685018X15173975498947; NAGAE-KURITZA, LEANDRO; WESTPHAL, PATRICK; SANTIN, ELIZABETH. Probióticos na avicultura. Ciência Rural, v. 44. n. 8, 2014, p. 1457–1465. 10.1590/0103-8478cr20120220; BROWN, KIRSTY; UWIERA, RICHAR, R.E.; KALMOKOFF, MARTIN L.; BROOKS, STEVE P .J.; INGLIS, DOUGLAS. Antimicrobial growth promoter use in livestock: a requirement to understand their modes of action to develop effective alternatives. International Journal Of Antimicrobial Agents, v. 49, n. 1, 2017, p. 12–24. https://doi.org/10.1016/j.ijantimicag.2016.08.006Test; QIN, CHUBIN; GONG, LI; ZHANG, XIAOPING; WANG, YUANYUAN; WANG, YIBIN; WANG, BAIKUI; LI, YALI; LI, WEIFEN. Effect of Saccharomyces boulardii and Bacillus subtilis B10 on gut microbiota modulation in broilers. Animal Nutrition, v. 55, n. 3, 2018, p. 63-67. https://doi.org/10.1016/j.aninu.2018.03.004Test; LONDOÑO-PÉREZ, SANTIAGO; PARRA-SUESCÚN, JAIME. Efecto de la adición de cepas probióticas sobre metabolitos sanguíneos en cerdos en crecimiento. Biotecnología en el Sector Agropecuario y Agroindustrial, v. 13, n. 2, 2015, p. 45-56. 10.18684/BSAA(13)49-56; AVIAGEN. Ross 308 AP. Objetivo de rendimiento. 2017. Disponible: http://es.aviagen.com/assets/Tech_Center/BB_Foreign_Language_Docs/Spanish_TechDocs/Ross308AP-Broiler-PO-2017-ES.pdfTest [citado 22 de Julio de 2020].; LÓPEZ-HERRERA, A.; MADRID-GARCÉS, T.A.; PARRA-SUESCÚN, J.E. La ingesta de aceite esencial de orégano (Lippia origanoides) mejora la morfología intestinal en Broilers. Archivos De Zootecnia, v. 66, n. 254, 2017, p. 287–299. https://doi.org/10.21071/az.v0i0.3876Test; CHÁVEZ, L.A.; LÓPEZ, A.; PARRA, J.E. Crecimiento y desarrollo intestinal de aves de engorde alimentadas con cepas probióticas. Archivos De Zootecnia, v. 65, n. 249, 2016, p. 51–58. https://doi.org/10.21071/az.v65i249.441Test; SAS/STAT®. Institute Inc. Statistical Analysis Systems Institute. User’s Guide, Version 9.4th Ed. Cary, NC: SAS Institute Inc. 2017. Disponible: https://www.sas.com/content/dam/SAS/en_us/doc/factsheet/stat-101372.pdfTest [citado 22 de Julio de 2020].; AHMAD, NAZIM; HAQUE, IQRAMUL; ALAM-MIAH, MOHAMMAD. Comparative analysis of body weight and serum biochemistry in broilers supplemented with some selected probiotics and antibiotic growth promoters. Journal Of Advanced Veterinary And Animal Research, v. 4, n. 3, 2017, p. 288–294. http://doi.org/10.5455/javar.2017.d226Test; ABRAMOWICZ, KATARZYNA; KRAUZE, MAGDALENA; OGNIK, KATARZYNA. The effect of a probiotic preparation containing Bacillus subtilis PB6 in the diet of chickens on redox and biochemical parameters in their blood. Annals Of Animal Science, 2019, p. 1-33. 10.2478/aoas-2018-0059; HEDAYATI, M.; KHALAJI, S.; MANAFI, M.; PIRANY, N. Efficacy of Bacillus subtilis and bacitracin methylene disalicylate on growth performance, digestibility, blood metabolites, immunity, and intestinal microbiota after intramuscular inoculation with Escherichia coli in broilers. Poultry Science, v. 95, n. 5, 2017, p. 1174–1183. https://doi.org/10.3382/ps/pew347Test; CALVO, E., CELI, PIETRO; KLUENTER, A.M., PÉREZ- SCHMEISSER, J.; VERLHAC, VIVIANE. Biomarkers of gastrointestinal functionality in animal nutrition and health. Animal Feed Science And Technology, v. 250, n. 1, 2019, p. 9–31. https://doi.org/10.1016/j.anifeedsci.2018.07.012Test; JAKHAR, K.K.; KUMAR, SARVAN; NEHRA, VIKAS; SHARMA, VIKASH. Biochemical studies in experimentally Escherichia coli infected broiler chicken supplemented with neem (Azadirachta indica) leaf extract. Veterinary World, v. 8, n. 11, 2015, p. 1340–1345. 10.14202/vetworld.2015.1340-1345; ISMAIL, HAGER-TAREK. Biochemical and hematological studies on the effect of Neem (Azadirachta indica) leaves aqueous extract on Newcastle disease vaccine and infection in broiler chickens. International Journal Of Recent Scientific Research, v. 8, n. 3, 2017, p. 15876–15884. http://dx.doi.org/10.24327/ijrsr.2017.0803.0002Test; HUSSEIN, E.; SELIM, S. Efficacy of yeast and multi-strain probiotic alone or in combination on growth performance, carcass traits, blood biochemical constituents, and meat quality of broiler chickens. Livestock Science, v. 216, n. 1, 2018, p. 153–159. https://doi.org/10.1016/j.livsci.2018.08.008Test; FOO, H.L.; HASHEMI, S.M.; LOH, T.C. Liquid metabolite of Lactobacillus plantarum and putrescine effects on growth, tissue polyamine, blood lipids and intestine morphology of broiler chickens. Iranian Journal Of Applied Animal Science, v. 8, n. 2, 2018, p. 333–342.; GONG, LI; WANG, BAIKUI; MEI, XIAOQIANG; XU, HAN; QIN, YAN; LI, WEIFEN; ZHOU, YINGSHAN. Effects of three probiotic Bacillus on growth performance, digestive enzyme activities, antioxidative capacity, serum immunity, and biochemical parameters in broilers. Animal Science Journal, v. 89, n. 11, 2018, p. 1561–1571. https://doi.org/10.1111/asj.13089Test; AL-BAADANI, HANI H.; ABUDABOS, ALAELDEIN; AL-MUFARREJ, SAUD; AL-ALI A.; ALHIDARY, IBRAHIM. Dietary supplementation of Bacillus subtilis, Saccharomyces cerevisiae and their symbiotic effect on serum biochemical parameters in broilers challenged with Clostridium perfringens. Journal Of Applied Animal Research, v. 46, n. 1, 2018, p.1064–1072. https://doi.org/10.1080/09712119.2018.1454325Test; ABBAS, GHULAM; ASIF-IQBAL, MUHAMMAD; RIAZ, MAHAM; SAJID, MUHAMMAD; ZAHID, OSAMA; WASIM-ABBAS, SYED; SAEED, HIRA; IMRAN-RAZA, ALI; ZOHAIB, MALIK. Comparative effect of different levels of probiotics (protexin) on hemato-chemical profile in broilers. Advances In Zoology And Botany, v. 6, n. 3, 2018, p. 84–87. 10.13189/azb.2018.060302; CORAZZIN, MIRCO; POURNAZARI, MARYAM; AA-QOTBI, ALI; SEIDAVI, ALIREZA. Prebiotics, probiotics and thyme (Thymus vulgaris) for broilers: performance, carcass traits and blood variables. Revista Colombiana De Ciencias Pecuarias, v. 30, n. 1, 2017, p. 3–10. 10.17533/udea.rccp.v30n1a01; XING, Y.; WANG, S.; FAN, J.; OSO, A.O.; KIM, S.W.; XIAO, D.; YANG, T.; LIU, G.; JIANG, G.; LI, Z.; LI, L.; ZHANG, B. Effects of dietary supplementation with lysine-yielding Bacillus subtilis on gut morphology, cecal microflora, and intestinal immune response of Linwu ducks. Journal Of Animal Science, v. 93, n. 7, 2015, p. 3449–3457. 10.2527/jas.2014-8090; CHEN, YUEPING; WEN, CHAO; ZHOU, YANMIN. Dietary synbiotic incorporation as an alternative to antibiotic improves growth performance, intestinal morphology, immunity and antioxidant capacity of broilers. Journal Of The Science Of Food And Agriculture, v. 98, n. 9, 2018, p. 3343–3350. https://doi.org/10.1002/jsfa.8838Test; GAO, Y.P.; MIN, Y.N.; YANG, H.L.; XU, Y.X. Effects of dietary supplementation of synbiotics on growth performance, intestinal morphology, sIgA content and antioxidant capacities of broilers. Journal Of Animal Physiology And Animal Nutrition, v. 100, n. 6, 2016, p. 1073–1080. 10.1111/jpn.12479; KING, A.J.; SAKSRITHAI, KETWEE; WILLITS, N.H. Production performance of laying hens at peak lay, sulfur compounds in manure, and selected serum profiles: efficacy of Lactobacillus species as probiotics. Animal Production Science, v. 60, n. 2, 2019, p. 296-304. 10.1071/AN18724; BRINCH, K.S.; GERAERT, P.A.; JACQUIER, V.; NELSON, A.; NIELSEN, P.; RHAYAT, L.; DEVILLARD, E. Bacillus subtilis strain specificity affects performance improvement in broilers. Poultry Science, v. 96, n. 7, 2017, p. 2274–2280. https://doi.org/10.3382/ps/pex018Test; KIM, I.H.; RUDEAUX, F.; UPADHAYA, S.D. Effects of inclusion of Bacillus subtilis (Gallipro) to energy- and protein-reduced diet on growth performance, nutrient digestibility, and meat quality and gas emission in broilers. Poultry Science, v. 98, n. 5, 2019, p. 2169–2178. https://doi.org/10.3382/ps/pey573Test; KIM, I.H.; PARK, J.H.; YUN, H.M. The effect of dietary Bacillus subtilis supplementation on the growth performance, blood profile, nutrient retention, and caecal microflora in broiler chickens. Journal Of Applied Animal Research, v. 46, n.1 , 2018, p. 868–872. https://www.tandfonline.com/loi/taar20Test; CHATTERJEE, PARESH-NATH; DAS, PARTHA-PRATIM; JAYARAMAN, SATHISHKUMAR; ROY, BARUN; SAINI, PRAKASH-CHANDRA. Use of Bacillus Subtilis PB6 as a potential antibiotic growth promoter replacement in improving performance of broiler birds. Poultry Science, v. 96, n. 8, 2017, p. 2614–2622. https://doi.org/10.3382/ps/pex079Test; GOODARZI-BOROOJENI, FARSHAD; VAHJEN, W.; MANNER, K.; BLANCH, A.; SANDVANG, D.; ZENTEK, J. Bacillus subtilis in broiler diets with different levels of energy and protein. Poultry Science, v. 97, n. 11, 2018, p. 3967–3976. 10.3382/ps/pey265; ANTHONY, R. et al. Guidelines for the Euthanasia of Animals. 5 ed. Illinois (United States): American Veterinary Medical Association, 2013, 121 p.; https://revistas.unicauca.edu.co/index.php/biotecnologia/article/view/1468Test

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