المؤلفون: Kh. M. Omarova, E. S.-А. Ibragimova, T. Kh.-M. Khashaeva, I. Kh. Magomedova, R. G. Omarova, E. G. Gereykhanova, Z. A. Abusueva, B. A. Abusueva

المصدر: Rossijskij Vestnik Perinatologii i Pediatrii, Vol 66, Iss 3, Pp 128-133 (2021)

مصطلحات موضوعية: medicine.medical_specialty, newborns, genetic structures, neurological disorders, Group ii, Early pregnancy factor, Reproductive technology, Pediatrics, behavioral disciplines and activities, RJ1-570, 03 medical and health sciences, 0302 clinical medicine, pregnant, late reproductive age, multiparous women, medicine, Asphyxia, Pregnancy, 030219 obstetrics & reproductive medicine, biology, business.industry, Obstetrics, medicine.disease, nervous system, Reproductive period, Pediatrics, Perinatology and Child Health, biology.protein, Gestation, High incidence, medicine.symptom, business, psychological phenomena and processes

الوصف: Objective.To assess the condition of newborns from women of the late reproductive period (LRP), depending on the parity of births.Material and methods.The authors examined 130 pregnant women and their 130 newborns. Group I consisted of 60 primiparouswomen of late reproductive period and their 60 newborns, Group II included 40 multiparous women of the late reproductive periodand their 40 newborns, Group III (control group) consisted of 30 healthy pregnant women aged from 18 to 25 years and their 30newborns. The authors performed a retrospective analysis of the gestation course and perinatal outcomes. Ultrasound and neurosonography were used among the instrumental research methods.Results.Women of the late reproductive period gave birth to children in a state of asphyxia twice more often, who develop neurologicaldisorders 1,5 times more often and complex postnatal adaptation and disorders of the perinatal period are twice more likely. Amongwomen of the late reproductive period, primiparous women gave birth to children with the most severe disorders.Conclusion.The high incidence of neurological diseases in children born from women of the late reproductive period is associatedwith age-related changes in their germ cells, the implementation of assisted reproductive technologies, and the intake of hormonaldrugs in early pregnancy. The data obtained should be taken into account by obstetricians in the course of pregnancy in women of latereproductive age; they should be included in the group of high risk of developing neurological disorders in children.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c30c471bf4ff64bcb0d8b3339f6daaTest
https://doi.org/10.21508/1027-4065-2021-66-3-128-133Test

المؤلفون: Tracey McMillan, Sarah M. Austin, Kristiina Hyrkas

المصدر: Journal of Obstetric, Gynecologic & Neonatal Nursing. 50:205-213

مصطلحات موضوعية: medicine.medical_specialty, Pregnancy, 030219 obstetrics & reproductive medicine, business.industry, Opioid overdose, Reproductive age, Critical Care Nursing, medicine.disease, Pediatrics, Heroin, 03 medical and health sciences, 0302 clinical medicine, Maternity and Midwifery, Emergency medicine, medicine, Gestation, 030212 general & internal medicine, business, medicine.drug

الوصف: In the United States, the number of deaths related to overdose of heroin and other opioids, specifically among women of reproductive age, has been rising. This case report adds new knowledge to the limited scientific literature currently available. We describe the care of a 30-year-old pregnant (31.4 weeks gestation) woman who was found unresponsive from a suspected opioid overdose in a friend’s home. In response to an unwitnessed cardiopulmonary arrest, the team initiated therapeutic hypothermia 12 hours after the event. Multiple interdisciplinary teams came together to care for this woman and fetus. Information sharing among care providers from multiple disciplines is needed to build expertise in managing the care of pregnant women who experience opioid overdose.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::657418e4325f749084d6985bb6ce8215Test
https://doi.org/10.1016/j.jogn.2020.11.003Test

المؤلفون: Mariya Alekseeva, Natalia Sergeeva, Rebeka Hakobova, Julia Vychristuck, Elena Selivanova, galina myandina

المصدر: Archiv Euromedica. 11:34-36

مصطلحات موضوعية: Cultural Studies, History, Recurrent genital herpes, Pediatrics, medicine.medical_specialty, Quality of life (healthcare), Literature and Literary Theory, business.industry, Medicine, Reproductive age, business

الوصف: Background: Current statistics show that the highest incidence of genital herpes is observed among women of reproductive age. Since these patients have an active lifestyle, frequent outbreaks of genital herpes can cause physical and psychological discomfort. Aim. To assess the quality of life of women of reproductive age with recurrent genital herpes. Methods: The quality of life in women suffering from recurrent genital herpes for more than 5 years (n=86) was evaluated. The control group included healthy women (n=91) according to the data of external genitalia examination and PCR diagnostics. The Health Status Survey (SF-36) in points was employed to measure the health status of women in both groups. Results: We established a significant difference between two groups of patients in terms of the influence of the following indicators on functional limitations: general health condition — 12.1±0.8 points; pain — 8.3±0.4 points; physical problems — 18,3±3,7; physical activity — 8.2±0.6 points (p

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::40f82a687254ed418040cbdb7745c278Test
https://doi.org/10.35630/2199-885x/2021/11/4.8Test

المؤلفون: Lucetta Dias, Karthi M

المصدر: International Journal of Research in Pharmaceutical Sciences. 12:199-202

مصطلحات موضوعية: Infertility, Pediatrics, medicine.medical_specialty, business.industry, Endometrial cancer, Reproductive age, Type 2 diabetes, Disease, medicine.disease, Anovulation, Lifestyle modification, medicine, Observational study, General Pharmacology, Toxicology and Pharmaceutics, business

الوصف: Most of the women in the reproductive age group are affected by PCOD. Emphasis on prevention of PCOD, as the incidents of PCOD, are increasing. The current incident of PCOD is (5%to 15%) is increasing fastly due to lifestyle and stress. It is also becoming a common problem amongst adolescent, developing soon after puberty. Amongst infertile women, about 15% to 20% of infertility cases are due to anovulation caused by PCOD. This study was done to assess the knowledge of PCOD among women and to make them aware of lifestyle modification is an important part of treatment. Some of the women who developed cardiovascular disease, hypertension, endometrial cancer and type 2 diabetes later in life appear to have suffered from PCOD in earlier years. A cross-sectional observational study was conducted in Chennai with 100 women of reproductive age (18~45 yrs) from January to June 2020 using standardized questionnaire. According to the study, 28% of the subjects are very well aware of the PCOD. 58% had expressed somewhat aware, 64% aware that Exercise help in the management of PCOD, in that 27% are maintaining diet and exercise every day. 14% of the respondents are not aware of the PCOD. This study indicated that more awareness should be made in the general public about PCOD as the majority of the participants are ignorant about lifestyle modification.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::67e78cccb3585f9c838ce5e3fa106684Test
https://doi.org/10.26452/ijrps.v12i1.3978Test

المؤلفون: Yu.Yu. Chebotareva

المصدر: РМЖ. Мать и дитя, Vol 4, Iss 3 (2021)

مصطلحات موضوعية: business.industry, RG1-991, medicine, Physiology, Reproductive age, Gynecology and obstetrics, General Medicine, Bacterial vaginosis, medicine.disease, business, Pediatrics, RJ1-570

الوصف: Yu.Yu. Chebotareva Rostov State Medical University, Rostov-on-Don, Russian Federation Aim: to assess the efficacy and safety of vaginal capsules containing metronidazole 100 mg and myconazole nitrate 100 mg in women with bacterial vaginosis (including recurrent vaginosis). Patients and Methods: 62 women were enrolled. Group 1 included 32 women with firstly diagnosed bacterial vaginosis. Group 2 included 30 women with recurrent bacterial vaginosis. Vaginal capsules containing 100 mg of metronidazole and 100 mg of miconazole nitrate (Gynocaps) or Gynocaps plus peroral metronidazole 250 mg twice daily (combined therapy) were prescribed. Group 1 and group 2 were divided into subgroups, i.e., 1A (n=20) and 1B (n=12), 2A (n=18) and 2B (n=12), based on treatment (monotherapy or combined therapy, respectively). Treatment efficacy was assessed 1 month and 12 months after completing treatment. Results: the major symptom in both groups was off-white vaginal discharge. Diffuse vulvar redness was more common in group 1 while petechiae were more common in group 2 (pLactobacillus spp. counts were reduced in all women, mixed infections were predominant. In group 2, significantly higher counts of anaerobic and yeast flora compared to group 1 were reported (p Conclusions: a 10-day treatment course of combined vaginal capsules containing metronidazole 100 mg and miconazole nitrate 100 mg improves clinical signs, eliminates complaints, and improves vaginal microflora owing to Lactobacillus growth without adverse reactions. In recurrent vaginosis, this agent should be used in combination with antibiotics. Keywords: bacterial vaginosis, active reproductive age, metronidazole, miconazole nitrate, Lactobacillus. For citation: Chebotareva Yu.Yu. Diagnosis and treatment of bacterial vaginosis during active reproductive age. Russian Journal of Woman and Child Health. 2021;4(3):218–224 (in Russ.). DOI: 10.32364/2618-8430-2021-4-3-218-224.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb2ee7dec9a041d6e4dbc15babbccfeTest
https://doi.org/10.32364/2618-8430-2021-4-3-218-224Test

المؤلفون: Jennifer Chae-Kim, Robert A Roman, Larisa Gavrilova-Jordan, Tongil 'Ti' Kim

المصدر: Journal of Fertility Preservation. 2:1-4

مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, business.industry, Reproductive tract, Cancer, Reproductive age, Retrospective cohort study, medicine.disease, Limited access, Infertility care, medicine, Hematologic malignancy, Fertility preservation, business

الوصف: Background. Fertility preservation (FP) prior to gonadotoxic cancer treatment is underutilized in the United States (US) due to limited access to care. Objective. We aimed to determine the utilization of a regional FP program in an underserved region in the Southeast US. Methods. We performed an institutional review board-approved retrospective cohort study of patients enrolled in the FP program at an academic tertiary medical center from 2014 to 2018. Results. Sixty-nine reproductive age patients were enrolled in the FP program, including 29 men and 40 women between 20 and 49 years of age. Cancer diagnoses among the enrolled patients included hematologic (n = 34), breast (n = 14), testicular (n = 11), reproductive tract (n = 7), and gastrointestinal (n = 3) malignancies. Patients with reproductive tract malignancies were found to have approximately 9.7 times greater odds of proceeding with FP than patients with hematologic malignancies (P Conclusion. Utilization of a regional FP program should be considered to increase access to care to this critical resource for patients desiring future family building. Patients with hematologic malignancy may face unique barriers to FP.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b14020bdb54f3e38736247db0382e896Test
https://doi.org/10.32371/jfp/246133Test

المؤلفون: Vishwesh B N

المصدر: International Journal of Ayurvedic Medicine. 11:394-398

مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, business.industry, Reproductive age, Disease, medicine.disease_cause, medicine, Itching, Observational study, medicine.symptom, Irritation, Presentation (obstetrics), business, Vaginal secretion

الوصف: Leucorrhoea is one of the commonest complaints among women of reproductive age group. An increase in the normal vaginal secretion develops physiologically at puberty, at ovulation, premenstrual phase and during pregnancy. Excessive discharge causes irritation and itching in the genitalia. Ayurveda explains this condition as Shwetha pradara. Though it is not a separate disease, clinically it has great relevance. This paper is an attempt to outline the details of Shwetha pradara as described in the classics and to illustrate its clinical presentation in 50 patients as an observational study.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::68f111d114f2d856d2076258bbfdeaceTest
https://doi.org/10.47552/ijam.v11i3.1547Test

المؤلفون: O. A. Pylaeva, K. Yu. Mukhin

المصدر: Russkij Žurnal Detskoj Nevrologii, Vol 15, Iss 2, Pp 17-41 (2020)

مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, Nausea, efficacy, women of reproductive age, Lamotrigine, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, children, medicine, 030212 general & internal medicine, tolerability, Generalized epilepsy, RC346-429, business.industry, Therapeutic effect, seizar, medicine.disease, Discontinuation, Tolerability, Pediatrics, Perinatology and Child Health, epilepsy, Neurology. Diseases of the nervous system, Neurology (clinical), Levetiracetam, medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug

الوصف: Background.We have accumulated extensive experience in the use of lamotrigine in patients with epilepsy; its mechanism of action, effectiveness, safety, and tolerability are well known. The results of numerous studies indicate its high efficacy and potentially better tolerabilitycompared to other drugs in the treatment of a wide range of epilepsy forms and epileptic syndromes (focal and generalized seizures). Thesecharacteristics of lamotrigine determined its priority administration as initial or alternative monotherapy in women with epilepsy.Objective:to review efficacy and tolerability of Seizar in patients with various forms of epilepsy based on long-term experience of using thisdrug in our center.Materials and methods.We analyzed therapeutic effects of Seizar in 22 patients aged between 3 and 34 years (mean age 15.3 years) treatedin Svt. Luka’s Institute of Child Neurology and Epilepsy. The sample included 8 adults and 14 children (under 18 years of age), including6 children aged from 3 to 12 years. Ten patients were male and twelve patients were female.Study participants were diagnosed with the following forms of epilepsy: idiopathic (genetic) generalized epilepsy (n = 9), idiopathic (genetic)focal epilepsy (n = 2), focal epilepsy of unknown etiology (n = 1), structural and probably structural focal epilepsy (n = 4), genetic and probably genetic epileptic encephalopathies (n = 6).Seizar was used as monotherapy in 9 patients and as an additional drug in 13 patients. Children aged 3 to 12 years received Seizar only as an additional drug in polytherapy (n = 6); patients aged between 12 and 18 years received it either as monotherapy (n = 4) or in addition to othertreatments (n = 4). Five adults received Seizar alone, whereas 3 adults received it as a part of polytherapy. In total, 9 participants receivedmonotherapy with Seizar and 13 participants received Seizar with other treatments. In two patients, combination therapy was successfullychanged to monotherapy with Seizar (they are currently receiving it as monotherapy). Seizar dose varied between 75 and 400 mg per daygiven in 1–2 portions. Importantly, prolonged action of Seizar and convenient dose of 200 mg per tablet allows its administration once a day.Currently, 4 patients (one 15-year-old girl and 3 adults) are receiving Seizar once a day (3 of them at bedtime and one of them in the morning).The follow-up period was between 4 months and 5 years.Results.Therapeutic remission with Seizar was achieved in 7 out of 22 patients (31.8 %); 10 patients (45.5 %) demonstrated at least 50 %reduction in seizure frequency; 5 patients (22,7 %) had no effect. None of the participants had seizure aggravation. Seizar was ceased in 2 patients(9 %) due to its inefficacy.Therefore, therapeutic effect (clinical remission or more than 50 % reduction in seizure frequency) was achieved in 17 out of 22 patients(77 %), which is a very good result considering the fact that all participants had severe forms of epilepsy.Seizar was most effective in patients with idiopathic epilepsy (≥50 % reduction in seizure frequency/clinical remission was observed in 9 out11 patients (81 %), including 5 patients receiving Seizar as monotherapy) and structural focal epilepsy or focal epilepsy of unknown etiology(≥50 % reduction in seizure frequency/clinical remission was observed in 4 out of 5 patients (80 %)). Positive effect was achieved in 4 outof 6 participants (66 %) with epileptic encephalopathies; this group included patients with extremely severe forms of epilepsy and resistanceto many antiepileptic drugs (AED).Seizar was well tolerated by patients: 72.8 % of them had no side effect and only 5 patients (22.7 %) had transient disorders of the centralnervous system and gastrointestinal tract (nausea, loss of appetite) that did not require discontinuation of the drug. Only one patient (4.5 %)required its cessation. In 4 female patients of reproductive age, Seizar was used to optimize therapy as a part of preparation for pregnancy.High efficacy and good tolerability of Seizar are confirmed by patients’ adherence to treatment: 19 of 22 patients included into the study (86 %)still continue to receive Seizar (the duration of follow-up period varies between 4 months and 5 years). Only 3 participants required drugdiscontinuation due to skin rash (n = 1; 4.5 %) and low efficacy (n = 2; 9 %).Conclusions.Over the past decades, clinicians have accumulated evidence of good safety and tolerability of lamotrigine, including such aspectsas its positive effect on cognitive functions, behavior, mood (including that in children), and particularly good safety profile in women of reproductive age.Lamotrigine and levetiracetam are currently considered the safest AED for women of reproductive age in terms of their impact on the neuroendocrine system of women, fertility, and potential teratogenic effect. The number of pregnancies among women receiving lamotrigine is significantly higher than that among women receiving other AED. Thus, the safety of lamotrigine during pregnancy (as well as other aspects of itssafety and tolerability) are studied much better compared to other AED. It is very important that lamotrigine is considered a safe drug.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f38b205ee138a299ae58e8ec22481dbTest
https://doi.org/10.17650/2073-8803-2020-15-2-17-41Test

المؤلفون: O. V. Dolenko

المصدر: International Medical Journal. :40-44

مصطلحات موضوعية: 03 medical and health sciences, Pediatrics, medicine.medical_specialty, 0302 clinical medicine, business.industry, medicine, 030209 endocrinology & metabolism, Reproductive age, 030204 cardiovascular system & hematology, Metabolic syndrome, medicine.disease, business

الوصف: The development of metabolic syndrome in women of reproductive age is one of the most common causes of anovulatory infertility, miscarriage in early pregnancy. In this pathology treatment in women there is used a comprehensive approach, which aims to restore specific functions, i.e. menstrual, secretory and reproductive ones. Important points are the detection of metabolic disorders in the patients before the formation of polycystic ovaries, normalization of body weight. In order to study the clinical effectiveness of the herbal drug "Glucemedin" in the combined treatment of metabolic syndrome in 40 women of reproductive age, a clinical and laboratory investigation was performed, also transvaginal ultrasound and body mass index were determined. In the first group of patients as the main treatment the metformin was prescribed hydrochloride as monotherapy in a dosage of 500 mg 2 times a day, in the second there was added phytodrug "Glucemedin" in a dosage of 1 capsule 3 times a day. The combined treatment showed a more pronounced dynamics of reduction of total and free cholesterol, low−density lipoprotein, triglycerides, atherogenic factor, decreased body mass index compared with the patients receiving metformin monotherapy. Based on analysis of the results of clinical and laboratory studies a high clinical efficiency of the herbal phytodrug "Glucemedin", which is stipulated with the pronounced effect on lipid spectrum of blood. The presence of natural components being a part of the phytodrug "Glucemedin", their high bioavailability, safety of the drug, no side effects and contraindications indicate its pronounced clinical effectiveness and feasibility of inclusion into the treatment of metabolic syndrome in women of childbearing age. Key words: metabolic syndrome, lipid profile, body mass index, transvaginal ultrasound, Glucemedin, clinical efficiency, combined treatment, women of reproductive age.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::faf71d960b1f420401d08ad17be449afTest
https://doi.org/10.37436/2308-5274-2020-3-8Test

المؤلفون: Chloe Andrews, Katherine H. Appel, Sabi Gurung, Robin Shrestha, Patrick Webb, Lynne M. Ausman, Elizabeth Marino Costello, Shibani Ghosh

المصدر: Maternal & Child Nutrition
Maternal and Child Nutrition, Vol 18, Iss 1, Pp n/a-n/a (2022)

مصطلحات موضوعية: Rural Population, RC620-627, Nutritional Status, women of reproductive age, malnutrition, Overweight, Logistic regression, Pediatrics, RJ1-570, Food group, Environmental health, Vegetables, Animal source foods, medicine, Animals, Humans, overweight, Nutritional diseases. Deficiency diseases, Bangladesh, anaemia, Nutrition and Dietetics, business.industry, Public Health, Environmental and Occupational Health, Obstetrics and Gynecology, Gynecology and obstetrics, Original Articles, medicine.disease, Diet, Malnutrition, Pediatrics, Perinatology and Child Health, RG1-991, Female, Original Article, Observational study, Underweight, medicine.symptom, business, Body mass index

الوصف: In rural Bangladesh, intake of nutrient‐rich foods, such as animal source foods (ASFs), is generally suboptimal. Diets low in nutrients and lacking in diversity put women of reproductive age (WRA) at risk of malnutrition as well as adverse birth outcomes. The objective of this study was to assess the relationship between maternal dietary diversity, consumption of specific food groups and markers of nutritional status, including underweight [body mass index (BMI)
Key messages Women's nutrition remains poor in rural Bangladesh, with high rates of underweight, overweight and anaemia.Women's Dietary Diversity Score (WDDS) was not systematically associated with underweight, overweight, or anaemia. This has implications for the widespread use of WDDS as a proxy for the quality of women's diet and nutrition.Consumption of specific food groups, including dark green leafy vegetables (DGLV), eggs and animal source foods (ASFs), is positively associated with women's nutrition.Consumption of ASFs, particularly fish, is especially protective against underweight (fish vs. no fish: odds ratio: 0.8, 95% confidence interval: 0.65–0.99, p

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fa52abffc8685de7cc787637fe7ff2Test
https://doi.org/10.1111/mcn.13287Test