نتائج البحث - "David J. Brooks"

1

Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson’s Disease Subtypes

المؤلفون: Casper Skjærbæk, Eva Schaeffer, Per Borghammer, Nathalie Van Den Berge, Tatyana D. Fedorova, Katrine B. Andersen, Jacob Horsager, Nicola Pavese, David J. Brooks, Daniela Berg, Karoline Knudsen

المصدر: Knudsen, K, Fedorova, T D, Horsager, J, Andersen, K B, Skjærbæk, C, Berg, D, Schaeffer, E, Brooks, D J, Pavese, N, Van Den Berge, N & Borghammer, P 2021, ' Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes ', Journal of Parkinson's Disease, vol. 11, no. 4, pp. 1677-1687 . https://doi.org/10.3233/JPD-212761Test

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Parkinson's disease, Dopamine, PROGRESSION, REM Sleep Behavior Disorder, Binding ratio, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Internal medicine, medicine, Humans, dopaminergic dysfunction, In patient, SCREENING QUESTIONNAIRE, Nigrostriatal degeneration, Tomography, Emission-Computed, Single-Photon, Dopamine Plasma Membrane Transport Proteins, business.industry, Putamen, Dopaminergic, Brain, Parkinson Disease, medicine.disease, PATHOLOGY, 030104 developmental biology, Endocrinology, SLEEP BEHAVIOR DISORDER, alpha-Synuclein, Sleep behavior, Neurology (clinical), Brainstem, business, brain- and body-first, asymmetry, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ab5bb40bc7fad9531656be8be43eb7Test
https://doi.org/10.3233/jpd-212761Test

2

Reduced Synaptic Density in Patients with Lewy Body Dementia: An [ 11 C ] UCB‐J PET Imaging Study

المؤلفون: Erik H. Danielsen, Per Borghammer, Malene Flensborg Damholdt, Casper Skjærbæk, Jacob Horsager, David J. Brooks, Anna C. Schacht, Hanne Gottrup, Allan K Hansen, Henriette Klit, Katrine B. Andersen

المصدر: Andersen, K B, Hansen, A K, Damholdt, M F, Horsager, J, Skjaerbaek, C, Gottrup, H, Klit, H, Schacht, A C, Danielsen, E H, Brooks, D J & Borghammer, P 2021, ' Reduced Synaptic Density in Patients with Lewy Body Dementia : An [ 11 C-]UCB-J PET Imaging Study ', Movement Disorders, vol. 36, no. 9, pp. 2057-2065 . https://doi.org/10.1002/mds.28617Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9750704b9dbf19797286345c50f195d4Test
https://doi.org/10.1002/mds.28617Test

3

Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers

المؤلفون: Per Borghammer, Karen Østergaard, Peter Parbo, Arne Møller, Kristian Stær, David J. Brooks, Nicola Pavese, Alicia Garrido, Eduardo Tolosa, Morten Gersel Stokholm, Mónica Serradell, María José Martí, Alex Iranzo

المصدر: Stokholm, M G, Garrido, A, Tolosa, E, Serradell, M, Iranzo, A, Ostergaard, K, Borghammer, P, Moller, A, Parbo, P, Staer, K, Brooks, D J, Jose Marti, M & Pavese, N 2020, ' Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers ', Journal of Neurology, vol. 267, no. 8, pp. 2296-2300 . https://doi.org/10.1007/s00415-020-09830-3Test
Journal of Neurology

مصطلحات موضوعية: 0301 basic medicine, PENETRANCE, medicine.medical_specialty, Parkinson's disease, Neurology, Dopamine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Asymptomatic, DISEASE, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, medicine, Humans, Movement disorders, Neuroinflammation, Subclinical infection, Original Communication, Microglia, business.industry, Parkinsonism, SYNUCLEINOPATHIES, Parkinson Disease, medicine.disease, nervous system diseases, PATHOLOGY, PET, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Clinical neurology, Mutation, Parkinson’s disease, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d9ae05a56f269dd603e6775f67cce3Test
https://doi.org/10.1007/s00415-020-09830-3Test

4

Imaging Familial and Sporadic Neurodegenerative Disorders Associated with Parkinsonism

المؤلفون: David J. Brooks

المصدر: Neurotherapeutics
Brooks, D J 2021, ' Imaging Familial and Sporadic Neurodegenerative Disorders Associated with Parkinsonism ', Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics . https://doi.org/10.1007/s13311-020-00994-4Test
Brooks, D J 2021, ' Imaging Familial and Sporadic Neurodegenerative Disorders Associated with Parkinsonism ', Neurotherapeutics, vol. 18, no. 2, pp. 753-771 . https://doi.org/10.1007/s13311-020-00994-4Test

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pathology, Neurology, 2-YEAR FOLLOW-UP, ALPHA-SYNUCLEIN, Dopamine, Neuroimaging, Disease, Review, 03 medical and health sciences, 0302 clinical medicine, POSITRON-EMISSION-TOMOGRAPHY, Parkinsonian Disorders, Genetic, Medicine, Dementia, Humans, Pharmacology (medical), Parkinson, IN-VIVO, Pharmacology, Lewy body, business.industry, Parkinsonism, Disease progression, Brain, Neurodegenerative Diseases, PROGRESSIVE SUPRANUCLEAR PALSY, medicine.disease, LEWY BODIES, Magnetic Resonance Imaging, Molecular Imaging, Functional imaging, F-18 DOPA PET, 030104 developmental biology, PET, SLEEP BEHAVIOR DISORDER, Positron-Emission Tomography, SPECT, Neurology (clinical), Neurosurgery, DIFFERENTIAL-DIAGNOSIS, business, 030217 neurology & neurosurgery, Atypical, MULTIPLE-SYSTEM ATROPHY, MRI

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ffc66a31764ee88b8fd6bcc963067eTest
https://pubmed.ncbi.nlm.nih.gov/33432494Test

5

Behavioural symptoms in Alzheimer’s disease are associated with white matter lesions (WML) volume and are independent of atrophy and hypometabolism

المصدر: Alzheimer's & Dementia. 16

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Disease, medicine.disease, Hyperintensity, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Atrophy, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Volume (compression)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2c882551449eec3ae5b2714dc4998e6cTest
https://doi.org/10.1002/alz.045223Test

6

Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer’s disease

المؤلفون: Rola Ismail, Kaj Blennow, David J. Brooks, Henrik Zetterberg, Peter Parbo, Lasse Stensvig Madsen, Thomas Vorup-Jensen, Simon Fristed Eskildsen

المصدر: Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-7 (2020)
Parbo, P, Madsen, L S, Ismail, R, Zetterberg, H, Blennow, K, Eskildsen, S F, Vorup-Jensen, T & Brooks, D J 2020, ' Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease ', Alzheimer's Research & Therapy, vol. 12, no. 1, 3 . https://doi.org/10.1186/s13195-019-0574-0Test

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Neurology, Precuneus, lcsh:RC346-429, 0302 clinical medicine, Cerebrospinal fluid, Neurofilament Proteins, Carbon Radioisotopes, Microglia, medicine.diagnostic_test, biology, Middle Aged, Magnetic Resonance Imaging, medicine.anatomical_structure, Female, medicine.symptom, medicine.medical_specialty, Neurofilament light, Cognitive Neuroscience, Prodromal Symptoms, Inflammation, Neuroprotection, lcsh:RC321-571, 03 medical and health sciences, Alzheimer Disease, medicine, Translocator protein, Humans, Cognitive Dysfunction, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, lcsh:Neurology. Diseases of the nervous system, Aged, PK11195, business.industry, Research, Magnetic resonance imaging, Isoquinolines, MCI, 030104 developmental biology, PET, Positron-Emission Tomography, biology.protein, Alzheimer, Neurology (clinical), Radiopharmaceuticals, business, 030217 neurology & neurosurgery, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6a0deb927dcc81eeef293d7bb0d6c7Test
http://europepmc.org/articles/PMC6941285Test

7

Tau tangles in Parkinson's disease: A 2-year follow-up flortaucipir PET study

المؤلفون: Karen Østergaard, Allan K Hansen, Rola Ismail, Per Borghammer, David J. Brooks, Peter Parbo

المصدر: Hansen, A K, Parbo, P, Ismail, R, Østergaard, K, Brooks, D J & Borghammer, P 2020, ' Tau Tangles in Parkinson's Disease : A 2-Year Follow-Up Flortaucipir PET Study ', Journal of Parkinson's Disease, vol. 10, no. 1, pp. 161-171 . https://doi.org/10.3233/JPD-191774Test

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, Parkinson's disease, positron emission tomography, TRACER, Contrast Media, 0601 Biochemistry and Cell Biology, 0302 clinical medicine, Cortex (anatomy), BINDING, Cerebral Cortex, SUBSTANTIA-NIGRA, medicine.diagnostic_test, Parkinson Disease, Middle Aged, neurofibrillary Tangles Melanins, Substantia Nigra, ALZHEIMERS-DISEASE, medicine.anatomical_structure, Positron emission tomography, Female, Monoamine oxidase B, Analysis of variance, Life Sciences & Biomedicine, medicine.medical_specialty, tau Proteins, Substantia nigra, MONOAMINE-OXIDASE-B, 03 medical and health sciences, Cellular and Molecular Neuroscience, POSITRON-EMISSION-TOMOGRAPHY, Neuromelanin, medicine, Humans, Dementia, BRAIN MAO-B, Cognitive Dysfunction, NEUROMELANIN, Aged, ACCUMULATION, Science & Technology, business.industry, Neurosciences, melanins, medicine.disease, 030104 developmental biology, nervous system, neurofibrillary tangles, Positron-Emission Tomography, CHOROID-PLEXUS, Parkinson’s disease, Neurology (clinical), Neurosciences & Neurology, business, 1109 Neurosciences, 030217 neurology & neurosurgery, Carbolines, Follow-Up Studies, dementia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b13133f2ce49b1290ea47a3d675716fTest
http://hdl.handle.net/10044/1/75673Test

8

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

المؤلفون: Jessica L. Teeling, Camilla Thygesen, Sussanne Petersen, Anne M. Landau, Athanasios Metaxas, Sultan Darvesh, David J. Brooks, Helene Audrain, Stefan J. Kempf, Bente Finsen, Marco Anzalone, Martin R. Larsen, Ramanan Vaitheeswaran

المصدر: Metaxas, A, Thygesen, C, Kempf, S J, Anzalone, M, Vaitheeswaran, R, Petersen, S, Landau, A M, Audrain, H, Teeling, J L, Darvesh, S, Brooks, D J, Larsen, M R & Finsen, B 2019, ' Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease ', Scientific Reports, vol. 9, no. 1, 15758 . https://doi.org/10.1038/s41598-019-52357-5Test
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Metaxas, A, Thygesen, C, Kempf, S J, Anzalone, M, Vaitheeswaran, R, Petersen, S, Landau, A M, Audrain, H, Teeling, J L, Darvesh, S, Brooks, D J, Larsen, M R & Finsen, B 2019, ' Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease ', Scientific Reports, vol. 9, 15758 . https://doi.org/10.1038/s41598-019-52357-5Test

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51362d3890afaf810421cc05e9610f0Test
https://findresearcher.sdu.dk:8443/ws/files/156242975/Ageing_and_amyloidosis_underlie.pdfTest

9

MAO-B Inhibitors Do Not Block In Vivo Flortaucipir([18F]-AV-1451) Binding

المؤلفون: Per Borghammer, Allan K Hansen, David J. Brooks

المصدر: Hansen, A K, Brooks, D J & Borghammer, P 2017, ' MAO-B Inhibitors Do Not Block In Vivo Flortaucipir([(18)F]-AV-1451) Binding ', Molecular Imaging and Biology . https://doi.org/10.1007/s11307-017-1143-1Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c85c2f58261574ae97221769fd92f98Test
https://doi.org/10.1007/s11307-017-1143-1Test

10

Widespread microglial activation in multiple system atrophy

المؤلفون: Nicole Cabanel, Zhangjie Su, Dorothee Kübler, Alexander Gerhard, Richard Dodel, Federico Turkheimer, Wolfgang H. Oertel, David J. Brooks, Tobias Wächter

المصدر: Mov. Disord. 34, 564-568 (2019)
Kuebler, D, Waechter, T, Cabanel, N, Su, Z, Turkheimer, F E, Dodel, R, Brooks, D J, Oertel, W H & Gerhard, A 2019, ' Widespread microglial activation in multiple system atrophy ', Movement Disorders, vol. 34, no. 4, pp. 564-568 . https://doi.org/10.1002/mds.27620Test
Movement Disorders

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Movement disorders, 1702 Cognitive Sciences, Medizin, 1106 Human Movement and Sports Sciences, Caudate nucleus, multiple system atrophy, microglia, DISEASE, neuroinflammation, 0302 clinical medicine, BINDING, BRAIN, Putamen, Brief Report, Brain, Middle Aged, medicine.anatomical_structure, Neurology, Female, medicine.symptom, Life Sciences & Biomedicine, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit, medicine.medical_specialty, Clinical Neurology, Microglia/metabolism, 03 medical and health sciences, Atrophy, Microglia, Multiple System Atrophy, Neuroinflammation, Pet, Pk11195, medicine, Humans, Anterior cingulate cortex, Aged, PK11195, Science & Technology, Neurology & Neurosurgery, business.industry, Precentral gyrus, 1103 Clinical Sciences, medicine.disease, Brain/diagnostic imaging, nervous system diseases, 030104 developmental biology, PET, nervous system, Multiple System Atrophy/diagnostic imaging, Positron-Emission Tomography, Orbitofrontal cortex, Brief Reports, Neurosciences & Neurology, Neurology (clinical), business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cc6a4c348b8e7056fd5f95db6bbcf7Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=55516Test

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