Current trends and advances of Quorum sensing inhibitors and their biotechnological applications

التفاصيل البيبلوغرافية
العنوان: Current trends and advances of Quorum sensing inhibitors and their biotechnological applications
المؤلفون: Shamshad, Samer, Rajagopal, Senthilkumar
المصدر: Indian Journal of Biochemistry and Biophysics (IJBB); IJBB Vol. 60 (4) [April 2023]; 255-280
بيانات النشر: Indian Journal of Biochemistry and Biophysics (IJBB)
سنة النشر: 2023
المجموعة: Online Publishing @ NISCAIR
مصطلحات موضوعية: Applications, Cell communication, Pathogen, QS inhibitors, QS
الوصف: Serious setbacks were witnessed in shrimp farming, the food industry, and the ship industry during the past three decades primarily due to bacterial pathogens that coordinate by quorum sensing (QS). The influence of bacterial pathogens utilizing QS. The impact of QS cell communication on public health is extremely disastrous in terms of spread, spectrum, apart from their economic impact. The overuse of antibiotics has increased drastically to battle bacterial infections, including tons of antibiotics are distributed in the biosphere. Due to the indiscriminate use of antibiotics, multiple antibiotic-resistant strains have emerged, as the antibiotic resistance genes are being transferred to bacteria of terrestrial animals, humans, and pathogens. The increased public awareness of the negative drawbacks caused by over-exposure to antibiotics, also the emergence of multiple antibiotic resistant pathogenic stains led to the search for alternatives and unique solutions. One such unconventional, promising method is the interruption of bacterial cell to cell communication, which is currently termed QS inhibition. Now-a-days, QS inhibition is the potential objective for antimicrobial chemotherapy. This review summarizes the regulatory factors that attenuate the QS activities of deadly pathogens and discusses their distinctive characteristics. Improving awareness of the natural roles of regulatory elements might be useful in unveiling inhibitor applications to understand how QS is inhibited in pathogenic bacteria by different QS inhibitors.
نوع الوثيقة: other/unknown material
وصف الملف: application/pdf
اللغة: English
العلاقة: http://op.niscair.res.in/index.php/IJBB/article/view/65104Test
DOI: 10.56042/ijbb.v60i4.65104
الإتاحة: https://doi.org/10.56042/ijbb.v60i4.65104Test
http://op.niscair.res.in/index.php/IJBB/article/view/65104Test
رقم الانضمام: edsbas.BCFF16E5
قاعدة البيانات: BASE