المؤلفون: Himanen, S. V., Puustinen, M. C., Da Silva, A. J., Vihervaara, Anniina, Sistonen, L.

المصدر: Nucleic Acids Research. 50(11):6102-6115

مصطلحات موضوعية: glutathione, heat shock transcription factor, heat shock transcription factor 1, heat shock transcription factor 2, menadione, RNA polymerase II, transcription factor Nrf2, unclassified drug, DNA binding protein, heat shock protein, Article, Cacybp gene, controlled study, differential expression analysis, down regulation, enhancer region, gene, gene activation, gene expression, genetic transcription, heat stress, Hs 578T cell line, human, human cell, immunofluorescence, oxidation reduction state, oxidative stress, promoter region, temperature, transcription initiation, upregulation, Western blotting, genetics, heat shock response, metabolism, DNA-Binding Proteins, Heat Shock Transcription Factors, Heat-Shock Proteins, Heat-Shock Response

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-326800Test
https://doi.org/10.1093/nar/gkac493Test

المؤلفون: Cornacchia, C., Marinelli, L., Di Rienzo, A., Dimmito, M. P., Serra, F., Di Biase, G., De Filippis, B., Turkez, H., Mardinoglu, Adil, Bellezza, I., Di Stefano, A., Cacciatore, I.

المصدر: European Journal of Medicinal Chemistry. 243

مصطلحات موضوعية: Antioxidant, Blood brain shuttle, Brain delivery system, Diketopiperazine, Levodopa, Parkinson's disease, Animals, Antioxidants, Blood-Brain Barrier, Caco-2 Cells, Carcinoma, Renal Cell, Diketopiperazines, Humans, Kidney Neoplasms, Oxidative Stress, Parkinson Disease, Rats, 8 hydroxydeoxyguanosine, free radical, glutathione, neurotoxin, piperazinedione, reactive oxygen metabolite, transcription factor Nrf2, animal cell, animal experiment, animal model, animal tissue, Article, biomembrane, biosynthesis, blood brain barrier, brain cortex, cancer model, cell culture, cell death, comet assay, controlled study, cytotoxicity, DNA damage, genetic marker, genotoxicity, half life time, human, hydrolysis, in vitro study, intestine fluid, male, newborn, nonhuman, rat, simulation, stomach juice, total antioxidant capacity, animal, Caco-2 cell line, kidney tumor, metabolism, renal cell carcinoma

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-328828Test
https://doi.org/10.1016/j.ejmech.2022.114746Test

المؤلفون: Lastres-Becker, I., Morgenstern, C., Demirdögen, B.C., Costa, V.M., Daiber, A., Foresti, R., Motterlini, R.

مصطلحات موضوعية: NRF2, HMOX1 gene, human, nonhuman, NQO1 gene, Nrf2 signaling, oxidative stress, protein function, Review, SRXN1 gene, translational research, TXNRD1 gene, Biomarker, Oxidative stress response, Target genes, Transcription factor, biological marker, glutamate cysteine ligase, glutamate cysteine ligase catalytic subunit, glutamate cysteine ligase modifier subunit, heme oxygenase 1, nicotinamide adenine dinucleotide phosphate quinone dehydrogenase 1, reduced nicotinamide adenine dinucleotide phosphate dehydrogenase, sulfiredoxin 1, thioredoxin reductase 1, transcription factor Nrf2, unclassified drug, body fluid, cell protection, GCLC gene

العلاقة: Redox Biology; DiÄŸer; https://doi.org/10.1016/j.redox.2024.103134Test; https://hdl.handle.net/20.500.11851/11559Test; 72; WOS:001233628200001; 2-s2.0-85190738421

الإتاحة: https://doi.org/20.500.11851/1155910.1016/j.redox.2024.103134Test
https://hdl.handle.net/20.500.11851/11559Test

المؤلفون: Chun, Kyung-Soo, Raut, Pawan Kumar, Kim, Do-Hee, Surh, Young-Joon

المساهمون: 서영준, Surh, Young-Joon

مصطلحات موضوعية: ANTIOXIDANT-RESPONSE ELEMENT, TRANSCRIPTION FACTOR NRF2, NF-KAPPA-B, HEME OXYGENASE-1 EXPRESSION, MEDIATED GENE-EXPRESSION, INDUCED OXIDATIVE STRESS, HUMAN SKIN KERATINOCYTES, PROSTATE-CANCER, EPIGENETIC REACTIVATION, TUMOR-GROWTH, Chemoprevention, NRF2, Oxidative stress, Phytochemicals, Redox signaling

العلاقة: Free Radical Biology and Medicine, Vol.172, pp.699-715; 141572; https://hdl.handle.net/10371/178055Test; 000685098400005; 2-s2.0-85111003352

الإتاحة: https://doi.org/10.1016/j.freeradbiomed.2021.06.031Test
https://hdl.handle.net/10371/178055Test

المؤلفون: Lennicke, C, Cocheme, H

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Redox regulation, ROS, Insulin signalling, Cysteine post-translational modification, FOXO, NRF2, Type-2 diabetes, TYROSINE-PHOSPHATASE 1B, HIGH-FAT DIET, TUMOR-SUPPRESSOR PTEN, TRANSCRIPTION FACTOR NRF2, HYDROGEN-PEROXIDE, REACTIVE OXYGEN, OXIDATIVE STRESS, REVERSIBLE INACTIVATION, PROTEIN PHOSPHATASE, MOLECULAR-MECHANISM, H(2)O(2), 0601 Biochemistry and Cell Biology, 1101 Medical Biochemistry and Metabolomics, 1115 Pharmacology and Pharmaceutical Sciences

العلاقة: Redox Biology; http://hdl.handle.net/10044/1/89187Test

الإتاحة: https://doi.org/10.1016/j.redox.2021.101964Test
http://hdl.handle.net/10044/1/89187Test

المؤلفون: Cuadrado, Antonio, Pajares, Marta, Benito, Cristina, Jiménez-Villegas, José, Escoll, Maribel, Fernández-Ginés, Raquel, García Yagüe, Angel J., Lastra, Diego, Manda, Gina, Rojo, Ana I., Dinkova-Kostova, Albena T.

المساهمون: UAM. Departamento de Bioquímica, UAM. Departamento de Medicina

مصطلحات موضوعية: COVID-19, Transcription factor NRF2, NF-KAPPA-B, oxidative stress, replication, inhibition, Acute respiratory distress syndrome (ARDS), Biología y Biomedicina / Biología

وصف الملف: application/pdf

العلاقة: Trends in Pharmacological Sciences; https://doi.org/10.1016/j.tips.2020.07.003Test; Comunidad de Madrid. B2017/BMD-3827/NRF24AD-CM; Trends in Pharmacological Sciences 41.9 (2020): 598-610; 0165-6147 (print); 1873-3735 (online); http://hdl.handle.net/10486/691775Test; 598; 610; 41

الإتاحة: https://doi.org/10.1016/j.tips.2020.07.003Test
http://hdl.handle.net/10486/691775Test

المؤلفون: Ansarin, A., Sabeti, Z., Ansarin, K., Zafari, V., Seyedrezazadeh, E., Shakerkhatibi, M., Asghari-Jafarabadi, M.

مصطلحات موضوعية: Antioxidant, Humans, Air pollution, Cytokines, NF-E2-related factor 2, Oxidative stress, Cell death, Gene expression, Nitric oxide, Respiratory system, Air pollutants, Exhaled breath condensate, Expression levels, Genes expression, PM 10, PM 2.5, Related factors, TNF α, atmospheric pollution, biomarker, correlation, gender, pollution exposure, young population, biological marker, interleukin 6, transcription factor Nrf2, tumor necrosis factor, adolescent, adverse event

العلاقة: Environmental Pollution; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11454/90132Test; https://doi.org/10.1016/j.envpol.2023.121463Test; 326

الإتاحة: https://doi.org/10.1016/j.envpol.2023.121463Test
https://hdl.handle.net/11454/90132Test

المؤلفون: Sabeti, Z., Ansarin, A., Ansarin, K., Zafari, V., Seyedrezazadeh, E., Shakerkhatibi, M., Asghari-Jafarabadi, M.

مصطلحات موضوعية: Air pollution, Antioxidant, Cytokines, NF-E2-related factor 2, Oxidative stress, Cell death, Gene expression, Nitric oxide, Respiratory system, Air pollutants, Exhaled breath condensate, Expression levels, Genes expression, PM 10, PM 2.5, Related factors, TNF ?, atmospheric pollution, biomarker, correlation, gender, pollution exposure, young population, biological marker, interleukin 6, transcription factor Nrf2, tumor necrosis factor, adolescent, adverse event, air pollutant

العلاقة: Environmental Pollution; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.1016/j.envpol.2023.121463Test; https://hdl.handle.net/11454/83001Test; 326; 2-s2.0-85150492308

الإتاحة: https://doi.org/10.1016/j.envpol.2023.121463Test
https://hdl.handle.net/11454/83001Test

المؤلفون: Felszeghy, Szabolcs, Viiri, Johanna, Paterno, Jussi J., Hyttinen, Juha M. T., Koskela, Ali, Chen, Mei, Leinonen, Henri, Tanila, Heikki, Kivinen, Niko, Koistinen, Arto, Toropainen, Elisa, Amadio, Marialaura, Smedowski, Adrian, Reinisalo, Mika, Winiarczyk, Mateusz, Mackiewicz, Jerzy, Mutikainen, Maija, Ruotsalainen, Anna-Kaisa, Kettunen, Mikko, Jokivarsi, Kimmo, Sinha, Debasish, Kinnunen, Kati, Petrovski, Goran, Blasiak, Janusz, Bjorkoy, Geir, Koskelainen, Ari, Skottman, Heli, Urtti, Arto, Salminen, Antero, Kannan, Ram, Ferrington, Deborah A., Xu, Heping, Levonen, Anna-Liisa, Tavi, Pasi, Kauppinen, Anu, Kaarniranta, Kai

المساهمون: Division of Pharmaceutical Biosciences, Drug Research Program, Drug Delivery Unit

مصطلحات موضوعية: Aging, Autophagy, Degeneration, Oxidative stress, Protein aggregation, Proteasome, TRANSCRIPTION FACTOR NRF2, ANTIOXIDANT RESPONSE, CELLS, MICE, RPE, DYSREGULATION, INFLAMMATION, DEGRADATION, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: This work was supported by the Kuopio University Hospital (KK) (Grant Number 5503743), the Finnish Eye Foundation (JJP, KK), the Finnish Funding Agency for Technology and Innovation (AK, KK), the Health Research Council of the Academy of Finland (KK, HS) (Grant Numbers 218050 and 296840), the Paivikki and Sakari Sohlberg Foundation (KK, HS), the Evald and Hilda Nissi Foundation and the Finnish Cultural Foundation-North-Savo (AKoi), the Lindsay Family Foundation and an anonymous donor for AMD research (DAF), National Science Centre, Poland (JB) (Grant number 2017/27/B/NZ3/00872). The researchers are very grateful to Mrs. Anne Seppanen, Mrs. Anne Karppinen, Mrs Virpi Miettinen, Mr. Anthony Rodriguez and Mr. Eric Barron for their skillful technical assistance.; Felszeghy , S , Viiri , J , Paterno , J J , Hyttinen , J M T , Koskela , A , Chen , M , Leinonen , H , Tanila , H , Kivinen , N , Koistinen , A , Toropainen , E , Amadio , M , Smedowski , A , Reinisalo , M , Winiarczyk , M , Mackiewicz , J , Mutikainen , M , Ruotsalainen , A-K , Kettunen , M , Jokivarsi , K , Sinha , D , Kinnunen , K , Petrovski , G , Blasiak , J , Bjorkoy , G , Koskelainen , A , Skottman , H , Urtti , A , Salminen , A , Kannan , R , Ferrington , D A , Xu , H , Levonen , A-L , Tavi , P , Kauppinen , A & Kaarniranta , K 2019 , ' Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration ' , Redox biology , vol. 20 , pp. 1-12 . https://doi.org/10.1016/j.redox.2018.09.011Test; 85053754150; ff7bb8b7-1d99-4a06-86d7-5558cc4d3ee0; http://hdl.handle.net/10138/299980Test; 000459361500001

الإتاحة: http://hdl.handle.net/10138/299980Test

المؤلفون: Quinti, L, Naidu, SD, Trager, U, Chen, X, Kegel-Gleason, K, Lleres, D, Connolly, C, Chopra, V, Low, C, Moniot, S, Sapp, E, Tousley, AR, Vodicka, P, Van Kanegan, MJ, Kaltenbach, LS, Crawford, LA, Fuszard, M, Higgins, M, Miller, JRC, Farmer, RE, Potluri, V, Samajdar, S, Meisel, L, Zhang, N, Snyder, A, Stein, R, Hersch, SM, Ellerby, LM, Weerapana, E, Schwarzschild, MA, Steegborn, C, Leavitt, BR, Degterev, A, Tabrizi, SJ, Lo, DC, DiFiglia, M, Thompson, LM, Dinkova-Kostova, AT, Kazantsev, AG

المصدر: PNAS - Proceedings of the National Academy of Sciences of the United States of America , 114 (23) E4676-E4685. (2017)

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, Huntington's disease, KEAP1/NRF2/ARE signaling, NRF2 inducer, antiinflammatory responses, human neural stem cells, TRANSCRIPTION FACTOR NRF2, CUL3-BASED E3 LIGASE, FUMARIC-ACID ESTERS, OXIDATIVE STRESS, PARKINSONS-DISEASE, NEURODEGENERATIVE DISEASES, MOUSE MODEL, PROTEASOMAL DEGRADATION, MICROGLIAL ACTIVATION, KEAP1-NRF2 SYSTEM

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/1554738/1/PNAS_final.pdfTest; https://discovery.ucl.ac.uk/id/eprint/1554738Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/1554738/1/PNAS_final.pdfTest
https://discovery.ucl.ac.uk/id/eprint/1554738Test/