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المؤلفون: Gloria Gutiérrez-Venegas, Berenice Fernández-Rojas, José Pedraza-Chaverri, Gustavo Ignacio Vázquez-Cervantes
المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 101-108 (2020)مصطلحات موضوعية: Antioxidant, Health, Toxicology and Mutagenesis, medicine.medical_treatment, ERK, extracellular signal-regulated kinases, 010501 environmental sciences, Toxicology, medicine.disease_cause, 01 natural sciences, GPx-1, glutathione peroxidase-1, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, chemistry.chemical_compound, 0302 clinical medicine, Carboxy-H2DCFDA, 6-carboxy-2´,7´ dichlorodihydrofluorescein diacetate, LTA, lipoteichoic acid, GSH, glutathione, ROS production, NOS, nitric oxide synthase, chemistry.chemical_classification, biology, Chemistry, OH•, hydroxyl radical, Glutathione peroxidase, Regular Article, respiratory system, IE, infective endocarditis, Catalase, H2O2, hydrogen peroxide, O2•¯, superoxide radical, Antioxidant enzymes, lipids (amino acids, peptides, and proteins), Lipoteichoic acid, FDA, fluorescein diacetate, JNK, c-jun N-terminal kinases, SOD-1, superoxide dismutase-1, AKT, protein kinase B, ONOO¯, peroxynitrite anion, Microbiology, RNS, reactive nitrogen species, Superoxide dismutase, 03 medical and health sciences, ROS, reactive oxygen species, lcsh:RA1190-1270, medicine, Nrf2, nuclear factor (erythroid-derived 2)-like 2, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, NO, nitric oxide, Reactive oxygen species, Glutathione, Oxidative stress, biology.protein, CAT, catalase, Infective endocarditis, DHE, dihydroethidium, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51499fcc0fda5a05a7ea44fe2d3e0ae6Test
https://doi.org/10.1016/j.toxrep.2019.12.007Test -
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المؤلفون: Annalise, Pfaff, Anna, Chernatynskaya, Hannah, Vineyard, Nuran, Ercal
المصدر: Biochemistry and Biophysics Reports
مصطلحات موضوعية: FDA, United States Food and Drug Administration, GSSG, glutathione disulfide, ATCC, American Type Culture Collection, OH•, hydroxyl radical, PBS, phosphate-buffered saline, NAC, N-acetylcysteine, tBHP, tert-butyl hydroperoxide, 7-AAD, 7-aminoactinomycin D, Glutathione, Cataract, Lens, HLE B-3, human (eye) lens epithelial cell line B-3, ROS, reactive oxygen species, FBS, fetal bovine serum, Oxidative stress, H2O2, hydrogen peroxide, Thiol, Carboxy-H2DCFDA, 6-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, GSH, glutathione, MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), NACA, N-acetylcysteine amide, MPG, N-(2-mercaptopropionyl)glycine, Antioxidant, EMEM, Eagle's minimum essential medium, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c6ad6a048992849fbae63780b9c9e9c3Test
https://pubmed.ncbi.nlm.nih.gov/35128081Test -
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المساهمون: The Wellcome Trust, University of St Andrews. Centre for Biophotonics, University of St Andrews. School of Psychology and Neuroscience, University of St Andrews. Institute of Behavioural and Neural Sciences
المصدر: Journal of Neuroscience Methods
مصطلحات موضوعية: SR-2, Serum replacement – 2, Culture, Neuronal network, Tretinoin, 5-fdu, 5-fluorodeoxyuridine, Mitochondrion, medicine.disease_cause, Article, ROS, Reactive oxygen species, Neuroblastoma, Cell Line, Tumor, Sv2, Synaptic vesicle glycoprotein 2, NeuN, Hexaribonucleotide Binding Protein-3, medicine, Humans, Nerve Growth Factors, HRP, Horse radish peroxidase, LDH, Lactate dehydrogenase, BDNF, Brain derived neurotrophic factor, Neurons, NGF, Nerve growth factor, TBS, Tris buffered saline, Sh sy5y neuroblastoma, biology, General Neuroscience, DAPI, 4’−6-diamidino-2-phenylindole, Cell Differentiation, DAS, HNE, 4-hydroxynonenol, medicine.disease, H2-DCFDA, 2',7'-Dichlorodihydrofluorescein diacetate, Mitochondria, TH, Tyrosine hydroxylase, Ageing, MTT, 3-(4,5-dimethylthiazol-2-yl)− 2,5-diphenyltetrazolium bromide, Oxidative stress, PBS, Phosphate buffered saline, DMEM, Dulbecco’s Modified Eagle Medium, biology.protein, RC0321, Neuroscience, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, Neurotrophin
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7cb4171cedd260207f5f3529ff5546Test
https://hdl.handle.net/10023/23789Test -
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المؤلفون: Patrick Yu-Wai-Man, Christoph Ufer, Lynn Bedford, David J. Boocock, Theodosis S. Theodosi, Aslihan Ugun-Klusek, Julia C. Fitzgerald, E. Ellen Billett, Florence Burté
المساهمون: Yu Wai Man, Patrick [0000-0001-7847-9320], Apollo - University of Cambridge Repository
المصدر: Redox Biology, Vol 20, Iss, Pp 167-181 (2019)
Redox Biology 20, 167-181 (2019). doi:10.1016/j.redox.2018.10.003
Redox Biologyمصطلحات موضوعية: SDS-PAGE, sodium dodecyl sulphate-polyacrylamide gel, Proteomics, 0301 basic medicine, genetics [Neuroblastoma], Proteome, CCCP, carbonyl cyanide 3-chlorophenylhydrazone, Clinical Biochemistry, genetics [Monoamine Oxidase], Fluorescent Antibody Technique, Gene Expression, mtDNA, Mitochondrial DNA, Protein oxidation, PD, Parkinson's disease, Biochemistry, DPBS, Dulbecco's Phosphate Buffered Saline, NADH, ß-Nicotinamide adenine dinucleotide, Neuroblastoma, 0302 clinical medicine, metabolism [Reactive Oxygen Species], Phosphorylation, lcsh:QH301-705.5, chemistry.chemical_classification, lcsh:R5-920, metabolism [Proto-Oncogene Proteins c-bcl-2], biology, Neurodegeneration, Immunohistochemistry, Mitochondria, 3. Good health, Cell biology, DMEM/F12, Dulbecco's Modified Eagles Medium/Ham's F-12 nutrient mixture, monoamine oxidase A, human, Proto-Oncogene Proteins c-bcl-2, Caspases, RT, room temperature, Monoamine oxidase A, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, MAO, monoamine oxidase, BCL2 protein, human, DCDHF, 2′,7′-Dichlorodihydroflourescein diacetate, Cell Survival, Monoamine oxidase, ETC, electron transport chain, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), metabolism [Neuroblastoma], SEM, standard error of the mean, Models, Biological, 03 medical and health sciences, ROS, reactive oxygen species, PBS, phosphate buffered saline, ddc:570, Cell Line, Tumor, Autophagy, medicine, Het, dihydroethidium, metabolism [Caspases], Humans, metabolism [Monoamine Oxidase], Monoamine Oxidase, LDH, Lactate dehydrogenase, Reactive oxygen species, Ac-DEVD-AMC, Acetyl-Asp-Glu-Val-Asp-7-amido-methyl coumarin, DMEM, Dulbecco's Modified Eagles Medium, Organic Chemistry, ATP, adenosine-5′-triphosphate, metabolism [Mitochondria], medicine.disease, Oxidative Stress, 030104 developmental biology, Monoamine neurotransmitter, chemistry, lcsh:Biology (General), DNPH, 2,4-Dinitrophenylhydrazine, DTT, dithiothreitol, biology.protein, qRT-PCR, quantitative reverse transcription PCR, genetics [Mitochondria], methods [Proteomics], Reactive Oxygen Species, 2-DG, 2-deoxy-D-glucose, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee6c7f7a07ce2d77e3885777776be6eTest
http://www.sciencedirect.com/science/article/pii/S2213231718307341Test -
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المؤلفون: Claudia Moriconi, Valerio Licursi, Giuseppe Lupo, Emanuela D'Acunto, Emanuele Cacci, Elena Miranda, Nicoletta Carucci, Noemi Antonella Guadagno, Rodolfo Negri, Antonella De Jaco, Paola S. Nisi
المصدر: Neurobiology of Disease
Neurobiology of Disease, Vol 103, Iss, Pp 32-44 (2017)مصطلحات موضوعية: 0301 basic medicine, Polymers, Epilepsies, Myoclonic, Protein conformational disease, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, FENIB, familial encephalopathy with neuroserpin inclusion bodies, GST, glutathione transferase, Cells, Cultured, ApoE, apolipoprotein E, Neurons, Cerebral Cortex, wild type, WT, GPx, glutathione peroxidase, Neurodegeneration, HRP, horseradish peroxidase, Prdx6, peroxiredoxin 6, 3. Good health, Scara, scavenger receptor class A, Neurology, Heredodegenerative Disorders, Nervous System, Intracellular, Familial encephalopathy with neuroserpin inclusion bodies, NS, neuroserpin, Cell Survival, Neuroserpin, Mice, Transgenic, Biology, Serpin, Article, lcsh:RC321-571, Neural progenitor cells, Oxidative stress, Serpin polymers, ER, endoplasmic reticulum, 03 medical and health sciences, SOD, superoxide dismutase, medicine, unfolded protein response, UPR, Animals, Humans, A1AT, alpha1 antitrypsin, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Serpins, Endoplasmic reticulum, Neuropeptides, Wild type, medicine.disease, Molecular biology, Oxidative Stress, 030104 developmental biology, NFκB, nuclear factor κB, Unfolded protein response, Aldh, aldehyde dehydrogenase, Dementia
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80be70f0ed1b0fc6e7f713e96db2e01Test
http://europepmc.org/articles/PMC5439028Test -
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المؤلفون: Jiansong Ji, Ri Cui, Xiaoxi Fan, Peng Zou, Fazong Wu, Weiqian Chen, Xi Chen, Qianqian Zhang, Rajamanickam Vinothkumar, Guang Liang, Zhongwei Zhao
المصدر: Redox Biol
Redox Biology, Vol 10, Iss C, Pp 78-89 (2016)
Redox Biologyمصطلحات موضوعية: 0301 basic medicine, ATF4, activating transcription factor 4, Cytotoxicity, Clinical Biochemistry, PI, propidium Iodide, Pharmacology, Biochemistry, JC-1, cationic carbocyanine dye, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, CHOP, CAAT/enhancer binding protein (C/EBP) homologous protein, cdc-2, cyclin-dependent kinase 1 (cell division cycle protein 2), lcsh:QH301-705.5, EF24, lcsh:R5-920, Kinase, HRP, horseradish peroxidase, Drug Synergism, Endoplasmic Reticulum Stress, PI3 kinase, phosphoinositide 3-kinase, Bcl2, B-cell lymphoma 2, Gene Expression Regulation, Neoplastic, DCF, dichlorodihydrofluorescein, mTORC, mTOR complex, 030220 oncology & carcinogenesis, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), Corrigendum, Research Paper, PARP, poly (ADP-ribose) polymerase, medicine.drug, Cell Survival, mTOR, mammalian target of rapamycin, MDM-2, murine double minute 2, Biology, Benzylidene Compounds, eIF2, eukaryotic initiation factor 2, ER, endoplasmic reticulum, 03 medical and health sciences, ROS, reactive oxygen species, Stomach Neoplasms, Cell Line, Tumor, medicine, Animals, Humans, Rapamycin, Piperidones, PI3K/AKT/mTOR pathway, DCFH-DA, 2′, 7′-dichlorodihydrofluorescein diacetate, Cell Proliferation, MDA, malondialdehyde, Sirolimus, 4E-BP-1, eukaryotic initiation factor 4E binding protein-1, Ki-67, nuclear protein associated with cell proliferation, Cell growth, PERK, protein kinase RNA-like endoplasmic reticulum kinase, Organic Chemistry, JNK Mitogen-Activated Protein Kinases, Cancer, Antitumor, C/EBP, CAAT/enhancer binding protein, JNK, c-Jun N terminal kinase, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, S6, S6 ribosomal protein, lcsh:Biology (General), Oxidative stress, Apoptosis, NAC, N-acetyl cysteine, Cancer cell, Unfolded protein response, Reactive Oxygen Species, Gastric cancer
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996fc2e0f8970a6c0fa2b5a280f19672Test
https://doi.org/10.1016/j.redox.2016.09.006Test -
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المؤلفون: Elisabeth Sehn, Christian Behl, Christof Hiebel, Franz H. Grus, Vanessa Felzen, Uwe Wolfrum, Caroline Manicam, Natarajan Perumal, Debapriya Chakraborty, Elisabeth Stürner
المصدر: Redox Biology
Redox Biology, Vol 24, Iss, Pp-(2019)مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, LFQ, Label-free quantification, LETM, Leucine zipper and EF-hand containing transmembrane protein, medicine.disease_cause, Biochemistry, CHX, Cycloheximide, 0302 clinical medicine, BNIP3, Bcl-2 interacting protein 3, RAPA, Rapamycin, PIK3C3, Class III PI3‐kinase, Phosphorylation, lcsh:QH301-705.5, Neurons, lcsh:R5-920, PolyUB, Polyubiquitin, Chemistry, BAG3, OPA1, Optic atrophy 1, TOR Serine-Threonine Kinases, WIPI1, WD repeat domain phosphoinositide-interacting protein 1, ATG, Autophagy related, TFEB, Transcription factor EB, Cell biology, Mitochondria, siRNA, Small interfering RNA, DLP1, Dynamin-like protein 1, LAMP1, Lysosomal‐associated membrane protein 1, PURO, Puromycin, lcsh:Medicine (General), Protein homeostasis, Research Paper, BafA1, Bafilomycin A1, LAMP2, Lysosomal‐associated membrane protein 2, Proteasome Endopeptidase Complex, RAB18, Member RAS oncogene, TUB, Tubulin, LC3, Light chain 3 protein, Oxidative phosphorylation, CTSD, Cathepsin D, Models, Biological, Cell Line, 03 medical and health sciences, Downregulation and upregulation, Macroautophagy, medicine, Autophagy, Humans, Adaptation, BAG1, Bcl-2-associated athanogene 1, BECN1, Beclin1, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, TEM, Transmission electron microscopy, Hsp70, Heat shock protein 70, Organic Chemistry, Autophagosomes, mTOR, Mammalian target of rapamycin, Hsp70, Oxidative Stress, 030104 developmental biology, Proteostasis, lcsh:Biology (General), CV, Canavanine, BAG3, Bcl-2-associated athanogene 3, MTT, (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide), Apoptosis Regulatory Proteins, Lysosomes, 030217 neurology & neurosurgery, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cc330b09215555a3158f06dbb32cb3Test
http://europepmc.org/articles/PMC6454062Test -
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المصدر: Redox Biology
مصطلحات موضوعية: Male, GSSG, glutathione disulfide, Nrf2, Nuclear factor erythroid 2-related factor 2, Clinical Biochemistry, Drug Evaluation, Preclinical, tBHP, tert-butyl hydroperoxide, Morin, medicine.disease_cause, environment and public health, Biochemistry, GST, glutathione S-transferase, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, chemistry.chemical_compound, PHLPP2, Fyn kinase, Catalytic Domain, Phosphoprotein Phosphatases, GSH, glutathione, DCFH-DA, 2′,7′-dichlorofluorescein diacetate, GR, glutathione reductase, Cells, Cultured, Membrane Potential, Mitochondrial, HO1, heme oxygenase 1, GPx, glutathione peroxidase, Protein Stability, ELISA, enzyme-linked immunosorbent assay, Analgesics, Non-Narcotic, respiratory system, NQO1, NAD(P)H quinine oxidoreductase 1, Cytoprotection, Cell biology, Molecular Docking Simulation, FITC, fluorescein isothiocyanate, Signal transduction, AIF, apoptosis inducing factor, Protein Binding, Research Paper, Transcriptional Activation, PVDF, polyvinylidene fluoride, JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolyl carbocyanine iodide, NF-E2-Related Factor 2, Primary Cell Culture, APAP, acetaminophen, SEM, standard error of the mean, digestive system, Nrf2, ROS, reactive oxygen species, FYN, medicine, Animals, Rats, Wistar, ARE, antioxidant redox element, Keap1, Kelch-like ECH-associated protein-1, Protein kinase B, Acetaminophen, Flavonoids, GAPDH, glyceraldehyde phosphate dehydrogenase, Organic Chemistry, Glutathione, TrxRed, thioredoxin reductase, KEAP1, chemistry, siRNA, small interfering RNA, Oxidative stress, Hepatocytes, Flavonoid, PHLPP2, PH-domain and Leucine rich repeat protein phosphatase 2, DHE, dihydroethidium
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0622271688b886a27ae2c0e62d3ec8Test
https://doi.org/10.1016/j.redox.2015.10.002Test -
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المؤلفون: Chee Wai Fong, Cheau Yih Tan, Han Kiat Ho, Tzuen Yih Saw
المصدر: Redox Biology, Vol 4, Iss C, Pp 308-320 (2015)
Redox Biologyمصطلحات موضوعية: PMSF, phenylmethanesulfonyl fluoride, Drug-induced liver injury, medicine.medical_treatment, Clinical Biochemistry, Nitric Oxide Synthase Type II, Tocopherols, DMEM/F12, Dulbecco’s modified Eagle's medium/Ham's F12, Pharmacology, medicine.disease_cause, Biochemistry, Antioxidants, ITS, insulin, transferrin, selenium, Lipid peroxidation, chemistry.chemical_compound, Mice, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, MPT, membrane potential transition, GST, glutathione-s-transferase, Vitamin E, TNF-α, tumor necrosis factor alpha, PMC, 2,2,5,7,8-pentamethyl-6-chromal, lcsh:QH301-705.5, Cell Line, Transformed, Liver injury, lcsh:R5-920, Tocopherol, Chemistry, Caspase 3, qRT-PCR, quantitative real time-polymerase chain reaction, NAPQI, N-acetyl-p-benzoquinoneimine, TGF-α, transforming growth factor alpha, Liver regeneration, Mitochondria, DILI, drug-induced liver injury, HPLC, high performance liquid chromatography, H2O2, hydrogen peroxide, mrpw, multiple reads per well, iNOS, inducible nitric oxide synthase, LPO, lipid peroxidation, Tocotrienol, HO-1, Heme oxygenase-1, Antioxidant, lcsh:Medicine (General), medicine.drug, Signal Transduction, Research Paper, DMSO, dimethylsulfoxide, NAPQI, DAD, diode array detector, Cell Survival, PCNA, proliferating cell nuclear antigen, bcl-X Protein, APAP, acetaminophen, FLD, fluorescence detector, Protective Agents, Nrf-2, nuclear factor erythroid 2-related factor, ROS, reactive oxygen species, PBS, phosphate buffered saline, Proliferating Cell Nuclear Antigen, medicine, Animals, IL-6, interleukin 6 (IL-6), Hepatoprotective Agent, Acetaminophen, Interleukin-6, Tumor Necrosis Factor-alpha, Organic Chemistry, MCB, monochlorobimane, GSH, L-glutathione reduced, Hydrogen Peroxide, α-T3, α-tocotrienol, medicine.disease, TP, tocopherol, SEM, standard error of means, Oxidative Stress, T3, tocotrienol, Gene Expression Regulation, lcsh:Biology (General), Hepatocytes, α-TP, α-tocopherol, BSA, bovine serum albumin, Lipid Peroxidation, Reactive Oxygen Species, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ab142df2b33df5b74bd59e3a7042d9Test
http://www.sciencedirect.com/science/article/pii/S2213231715000142Test -
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المصدر: DNA Repair
مصطلحات موضوعية: DSBs, DNA-double strand breaks, Pyrrolidines, Antioxidant, PDTC, pyrrolidine dithiocarbamate, medicine.medical_treatment, pATM, phosphorylated ATM, Gene Expression, Cell Cycle Proteins, Carboxy-H2DCFDA, 5-(and-6)-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, Ataxia Telangiectasia Mutated Proteins, medicine.disease_cause, Biochemistry, Antioxidants, 0302 clinical medicine, LDL, low-density lipoprotein, DNA Breaks, Double-Stranded, EA.hy926 cells, Phosphorylation, Colony forming efficiency assay, chemistry.chemical_classification, 0303 health sciences, p21, ROS, DNA-Binding Proteins, Lipoproteins, LDL, 030220 oncology & carcinogenesis, lipids (amino acids, peptides, and proteins), Cyclin-Dependent Kinase Inhibitor p21, Cell Survival, Protein Serine-Threonine Kinases, Biology, Article, Cell Line, ATM-I, ATM-kinase-inhibitor, 03 medical and health sciences, ATM, A-T mutated protein, ROS, reactive oxygen species, Thiocarbamates, medicine, Humans, Viability assay, Modified LDL, MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide, Protein Kinase Inhibitors, Molecular Biology, Transcription factor, 030304 developmental biology, Reactive oxygen species, Tumor Suppressor Proteins, Endothelial Cells, Cell Biology, Fibroblasts, Atherosclerosis, Hydrogen peroxide, Molecular biology, Oxidative Stress, DNA-double-strand breaks, DCF, dichlorofluorescein, oxLDL, oxidized low-density lipoprotein, chemistry, Cell culture, γ-H2AX, phosphorylated H2AX, Reactive Oxygen Species, A-T, Ataxia telangiectasia, Oxidative stress, Lipoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd467cd78b317982f01a978de6a36eddTest
https://doi.org/10.1016/j.dnarep.2011.05.004Test