المؤلفون: Choi, Roy B, Bullock, Whitney A, Hoggatt, April M, Loots, Gabriela G, Genetos, Damian C, Robling, Alexander G

المصدر: JBMR Plus. 5(5)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Osteoporosis, Musculoskeletal, BONE ANABOLISM, OSTEOPOROSIS, SCLEROSTIN Dkk1, Wnt, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8tj8j8vcTest

المؤلفون: Donham, Cristine, Chicana, Betsabel, Robling, Alexander G, Mohamed, Asmaa, Elizaldi, Sonny, Chi, Michael, Freeman, Brian, Millan, Alberto, Murugesh, Deepa K, Hum, Nicholas R, Sebastian, Aimy, Loots, Gabriela G, Manilay, Jennifer O

المصدر: International Journal of Molecular Sciences. 22(17)

مصطلحات موضوعية: Stem Cell Research, Osteoporosis, Stem Cell Research - Nonembryonic - Non-Human, Hematology, Aging, Adaptor Proteins, Signal Transducing, Animals, Antibodies, Monoclonal, Bone Marrow, Cytokines, Female, Gene Knockout Techniques, Hematopoietic Stem Cells, Inflammation, Male, Mice, Mice, Knockout, Myelopoiesis, osteoimmunology, osteopetrosis, genetic animal models, aging, Other Chemical Sciences, Genetics, Other Biological Sciences, Chemical Physics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1wc135k1Test

المؤلفون: Bullock, Whitney A, Hoggatt, April M, Horan, Daniel J, Elmendorf, Andrew J, Sato, Amy Y, Bellido, Teresita, Loots, Gabriela G, Pavalko, Fredrick M, Robling, Alexander G

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Osteoporosis, 2.1 Biological and endogenous factors, Aetiology, Biological Sciences, Cell Biology, Molecular Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2b90p0drTest

المؤلفون: Bullock, Whitney A, Hoggatt, April M, Horan, Daniel J, Lewis, Karl J, Yokota, Hiroki, Hann, Steven, Warman, Matthew L, Sebastian, Aimy, Loots, Gabriela G, Pavalko, Fredrick M, Robling, Alexander G

المصدر: Journal of Bone and Mineral Research. 34(10)

مصطلحات موضوعية: Osteoporosis, 2.1 Biological and endogenous factors, Aetiology, Musculoskeletal, Animals, Bone Density, Mechanotransduction, Cellular, Mice, Mice, Transgenic, Osteocytes, Osteogenesis, Tibia, X-Ray Microtomography, beta Catenin, beta-CATENIN, CTNNB1, WNT, DISUSE, OSTEOPOROSIS, β-CATENIN, Biological Sciences, Engineering, Medical and Health Sciences, Anatomy & Morphology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0976w1ffTest

المؤلفون: Yee, Cristal S, Manilay, Jennifer O, Chang, Jiun C, Hum, Nicholas R, Murugesh, Deepa K, Bajwa, Jamila, Mendez, Melanie E, Economides, Aris E, Horan, Daniel J, Robling, Alexander G, Loots, Gabriela G

المصدر: Journal of Bone and Mineral Research. 33(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Stem Cell Research, Stem Cell Research - Nonembryonic - Non-Human, Osteoporosis, Musculoskeletal, Adaptor Proteins, Signal Transducing, Animals, B-Lymphocytes, Bone Marrow, Cancellous Bone, Cell Lineage, Collagen Type X, Extracellular Matrix Proteins, Female, Femur, Gene Deletion, Glycoproteins, Homeodomain Proteins, Integrases, Intercellular Signaling Peptides and Proteins, Lumbar Vertebrae, Lymphocytes, Mesenchymal Stem Cells, Mice, Inbred C57BL, Organ Size, Osteoblasts, Osteogenesis, Phenotype, X-Ray Microtomography, SCLEROSTIN, MSC, OSTEOBLAST, OSTEOCYTE, CHONDROCYTE, WnT SIGNALING, WnT, Biological Sciences, Engineering, Medical and Health Sciences, Anatomy & Morphology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3c4679hbTest

المؤلفون: Witcher, Phillip C, Miner, Sara E, Horan, Daniel J, Bullock, Whitney A, Lim, Kyung-Eun, Kang, Kyung Shin, Adaniya, Alison L, Ross, Ryan D, Loots, Gabriela G, Robling, Alexander G

المصدر: JCI Insight. 3(11)

مصطلحات موضوعية: Aging, Osteoporosis, Clinical Research, Aetiology, 2.1 Biological and endogenous factors, Musculoskeletal, Adaptor Proteins, Signal Transducing, Anabolic Agents, Animals, Antibodies, Neutralizing, Bone Morphogenetic Proteins, Disease Models, Animal, Female, Femur, Genetic Markers, Glycoproteins, Humans, Hyperostosis, Intercellular Signaling Peptides and Proteins, Loss of Function Mutation, Male, Mice, Osteocytes, Osteogenesis, Spine, Syndactyly, Treatment Outcome, Up-Regulation, Wnt Signaling Pathway, X-Ray Microtomography, Bone Biology, Osteoclast/osteoblast biology, Therapeutics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4p73c52cTest

المؤلفون: Robling, Alexander G, Kang, Kyung Shin, Bullock, Whitney A, Foster, William H, Murugesh, Deepa, Loots, Gabriela G, Genetos, Damian C

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Stem Cell Research, Genetics, Osteoporosis, Stem Cell Research - Nonembryonic - Non-Human, 1.1 Normal biological development and functioning, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, Musculoskeletal, Adaptation, Physiological, Adaptor Proteins, Signal Transducing, Animals, Biomechanical Phenomena, Bone Morphogenetic Proteins, Enhancer Elements, Genetic, Female, Glycoproteins, Intercellular Signaling Peptides and Proteins, Mice, Mice, Knockout, Mice, Transgenic, Osteocytes, Osteogenesis, RNA, Untranslated, Sost, Sclerostin, Mechanotransduction, ECR5, Enhancer, Skeleton, Disuse, Biological Sciences, Engineering, Medical and Health Sciences, Endocrinology & Metabolism, Clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7sk2x2bjTest

المؤلفون: Choi, Roy B., Hoggatt, April M., Horan, Daniel J., Rogers, Emily Z., Hong, Jung Min, Robling, Alexander G.

المساهمون: Anatomy, Cell Biology and Physiology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Wnt, Sclerostin Dkk1, Bone anabolism, Osteoporosis

وصف الملف: application/pdf

العلاقة: Aging and Disease; Choi RB, Hoggatt AM, Horan DJ, Rogers EZ, Hong JM, Robling AG. Targeting Sclerostin and Dkk1 at Optimized Proportions of Low-Dose Antibody Achieves Similar Skeletal Benefits to Higher-Dose Sclerostin Targeting in the Mature Adult and Aged Skeleton. Aging Dis. 2022;13(6):1891-1900. Published 2022 Dec 1. doi:10.14336/AD.2022.0315; https://hdl.handle.net/1805/35912Test

الإتاحة: https://doi.org/10.14336/AD.2022.0315Test
https://hdl.handle.net/1805/35912Test

المؤلفون: Collette, Nicole M, Yee, Cristal S, Hum, Nicholas R, Murugesh, Deepa K, Christiansen, Blaine A, Xie, LiQin, Economides, Aris N, Manilay, Jennifer O, Robling, Alexander G, Loots, Gabriela G

مصطلحات موضوعية: Femur, Bony Callus, Periosteum, Osteoblasts, Stem Cells, Mesenchymal Stem Cells, Animals, Mice, Inbred C57BL, Actins, Bone Morphogenetic Proteins, Organ Size, Fracture Healing, Cell Differentiation, Cell Proliferation, Gene Deletion, Calcification, Physiologic, Osteogenesis, Phenotype, X-Ray Microtomography, Wnt Signaling Pathway, Nestin, Biomechanical Phenomena, Cancellous Bone, Cortical Bone, Sp7 Transcription Factor, Bone regeneration, Ectodin, Fracture repair, Sost, Sost-like, Sostdc1, Usag-1, Wise, Wnt signaling, Adaptor Proteins, Signal Transducing, Stem Cell Research, Osteoporosis, Stem Cell Research - Nonembryonic - Non-Human, Regenerative Medicine, 2.1 Biological and endogenous factors, Aetiology, Musculoskeletal, Biological Sciences, Engineering, Medical and Health Sciences, Endocrinology & Metabolism

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/10c8v4h9Test

المؤلفون: Knapik, Derrick M, Perera, Priyangi, Nam, Jin, Blazek, Alisa D, Rath, Björn, Leblebicioglu, Binnaz, Das, Hiranmoy, Wu, Lai Chu, Hewett, Timothy E, Agarwal, Suresh K, Robling, Alexander G, Flanigan, David C, Lee, Beth S, Agarwal, Sudha

المصدر: Antioxidants and Redox Signaling. 20(6)

مصطلحات موضوعية: Osteoporosis, Bioengineering, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Musculoskeletal, Animals, Bone and Bones, Humans, Inflammation, Mechanotransduction, Cellular, NF-kappa B, Wounds and Injuries, Biochemistry and Cell Biology, Medical Biochemistry and Metabolomics, Pharmacology and Pharmaceutical Sciences, Biochemistry & Molecular Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/96w3r56rTest