نتائج البحث - "Frédéric Blanchard"

1

دورية أكاديمية

Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration

المؤلفون: Paul Humbert, Meadhbh Á. Brennan, Noel Davison, Philippe Rosset, Valérie Trichet, Frédéric Blanchard, Pierre Layrolle

المصدر: Frontiers in Immunology, Vol 10 (2019)

مصطلحات موضوعية: osteoimmunology, mesenchymal stromal cell, calcium phosphate biomaterial, bone regeneration, osteoclast, immune modulation, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fimmu.2019.00663/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/aab7e7e2a2cb45e0b63a95c1a062a192Test

View record in DOAJ

النص الكامل

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MicroRNA‐17‐5p Reduces Inflammation and Bone Erosions in Mice With Collagen‐Induced Arthritis and Directly Targets the JAK/STAT Pathway in Rheumatoid Arthritis Fibroblast‐like Synoviocytes

المؤلفون: Frédéric Blanchard, Benoit Le Goff, Carl S. Goodyear, Pauline Preuss, Benjamin Ory, Shatakshi Sood, Steven Georges, Ursula Fearon, Thibaut Quillard, Aurélie Najm, Douglas J. Veale, François-Marie Masson

المساهمون: Service de rhumatologie [Nantes], Université de Nantes (UN)-Hôtel-Dieu-Centre hospitalier universitaire de Nantes (CHU Nantes), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Sarcomes osseux et remodelage des tissus calcifiés - Phy-Os [Nantes - INSERM U1238] (Phy-Os), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Bretagne Loire (UBL)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Equipe Labellisée LIGUE 2012 [Nantes]

المصدر: Arthritis & rheumatology
Arthritis & rheumatology, Wiley, 2020, ⟨10.1002/art.41441⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Immunology, Arthritis, Inflammation, Proinflammatory cytokine, Arthritis, Rheumatoid, Mice, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Osteoclast, medicine, Animals, Humans, Immunology and Allergy, STAT3, B cell, Cell Proliferation, Janus Kinases, biology, business.industry, Synovial Membrane, Fibroblasts, medicine.disease, Arthritis, Experimental, Synoviocytes, MicroRNAs, STAT Transcription Factors, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Rheumatoid arthritis, Cancer research, biology.protein, Cytokines, Tumor necrosis factor alpha, medicine.symptom, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c571e8cbb277887258fd44d100e2cc34Test
https://hal.archives-ouvertes.fr/hal-03004321Test

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Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration

المؤلفون: Paul Humbert, Meadhbh Á. Brennan, Noel Davison, Philippe Rosset, Valérie Trichet, Frédéric Blanchard, Pierre Layrolle

المساهمون: Sarcomes osseux et remodelage des tissus calcifiés - Phy-Os [Nantes - INSERM U1238] (Phy-Os), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Bretagne Loire (UBL)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Harvard University [Cambridge], MERLN Institute for Technology-Inspired Regenerative Medicine [Maastricht, Netherlands], Instructure Labs B.V. [The Hague, Netherlands], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Bretagne Loire (UBL)-Centre hospitalier universitaire de Nantes (CHU Nantes), maurice, sandrine

المصدر: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2019, 10, ⟨10.3389/fimmu.2019.00663⟩

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3ed60318a0287af242b0b4316936fe85Test
https://pubmed.ncbi.nlm.nih.gov/31001270Test

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BYL719, a new α-specific PI3K inhibitor: Single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma

المؤلفون: Françoise Rédini, Marc Baud' Huin, Frédéric Blanchard, Dominique Heymann, Rachel Lanel, Séverine Battaglia, Céline Charrier, Frédéric Lézot, Bérengère Gobin, Francois Lamoureux, Benjamin Ory

المصدر: International Journal of Cancer. 136:784-796

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f0daacc0f289cf3afa4c21466dae095aTest
https://doi.org/10.1002/ijc.29040Test

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Direct anti-cancer effect of oncostatin M on chondrosarcoma

المؤلفون: Stéphanie Ponsolle, Ronan Le Bot, Anne Riet, Carl D. Richards, Pierre J. Guihard, Séverine Battaglia, Frédéric Blanchard, Françoise Rédini, Céline Charrier, Dominique Heymann, François Gouin, Bénédicte Brounais, Emmanuelle David

المصدر: International Journal of Cancer. 128:1822-1835

مصطلحات موضوعية: Male, musculoskeletal diseases, Cancer Research, Pathology, medicine.medical_specialty, Osteolysis, Angiogenesis, Blotting, Western, Chondrosarcoma, Osteoclasts, Antineoplastic Agents, Apoptosis, Core Binding Factor Alpha 1 Subunit, Oncostatin M, Adenoviridae, Rats, Sprague-Dawley, Mice, Osteoclast, Matrix Metalloproteinase 13, Tumor Cells, Cultured, medicine, Animals, RNA, Messenger, Cell Proliferation, biology, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Cell Cycle, RANK Ligand, fungi, Janus Kinase 3, Cell Differentiation, SOX9 Transcription Factor, medicine.disease, Rats, Survival Rate, STAT1 Transcription Factor, medicine.anatomical_structure, Oncology, RANKL, biology.protein, Osteosarcoma, Sarcoma, Tumor Suppressor Protein p53, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6f3a06a96db7f413c9f57285eabb05Test
https://doi.org/10.1002/ijc.25776Test

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BYL719, a new α-specific PI3K inhibitor: Single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma

المؤلفون: Bérengère, Gobin, Marc Baud', Huin, François, Lamoureux, Benjamin, Ory, Céline, Charrier, Rachel, Lanel, Séverine, Battaglia, Françoise, Redini, Frédéric, Lezot, Frédéric, Blanchard, Dominique, Heymann

المساهمون: Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Equipe LIGUE Nationale Contre le Cancer 2012, Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Centre hospitalier universitaire de Nantes (CHU Nantes), Department of Oncology and Metabolism [Sheffield, UK], The University of Sheffield [Sheffield, U.K.]

المصدر: International Journal of Cancer
International Journal of Cancer, Wiley, 2015, 136 (4), pp.784-796. ⟨10.1002/ijc.29040⟩

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ab939e622b530751bf3265414ed26845Test
https://www.hal.inserm.fr/inserm-01644799Test

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Characterization of osteoprotegerin binding to glycosaminoglycans by surface plasmon resonance: Role in the interactions with receptor activator of nuclear factor κB ligand (RANKL) and RANK

المؤلفون: Frédéric Blanchard, P Vusio, Sandrine Théoleyre, Françoise Rédini, Yannick Fortun, Marc Padrines, S. Ricard-Blum, John T Gallagher, S. Kwan Tat, Dominique Heymann

المصدر: Biochemical and Biophysical Research Communications. 347:460-467

مصطلحات موضوعية: musculoskeletal diseases, Time Factors, Blotting, Western, Biophysics, Oligosaccharides, Receptors, Cytoplasmic and Nuclear, Binding, Competitive, Models, Biological, Biochemistry, Receptors, Tumor Necrosis Factor, Dermatan sulfate, Cell Line, chemistry.chemical_compound, Sulfation, Osteoprotegerin, Osteoclast, medicine, Humans, Chondroitin sulfate, Molecular Biology, Glycoproteins, Glycosaminoglycans, Membrane Glycoproteins, Receptor Activator of Nuclear Factor-kappa B, biology, Heparin, Sulfates, Chemistry, RANK Ligand, Cell Biology, Heparan sulfate, Surface Plasmon Resonance, Cell biology, Kinetics, medicine.anatomical_structure, RANKL, biology.protein, Carrier Proteins, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095f941c7dc774c03214e527aec5d446Test
https://doi.org/10.1016/j.bbrc.2006.06.120Test

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Novel anti-cancer strategy in bone tumors by targeting molecular and cellular modulators of bone resorption

المؤلفون: Françoise Rédini, Carmen Ruiz, Frédéric Blanchard, Francois Lamoureux, Julie Rousseau, Dominique Heymann, Bénédicte Brounais

المصدر: Recent patents on anti-cancer drug discovery. 3(3)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963b6874766da838892dc9d55d0fb6aeTest
https://pubmed.ncbi.nlm.nih.gov/18991786Test

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Interleukin-6 inhibits receptor activator of nuclear factor kappaB ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: key role of Serine727 phosphorylation of signal transducer and activator of transcription 3

المؤلفون: Dominique Heymann, Marc Baud'huin, Frédéric Blanchard, Martine Berreur, Laurence Duplomb, Céline Charrier, Valérie Trichet

المساهمون: Heymann, D, Physiopathologie de la résorption osseuse et thérapie des tumeurs osseuses primitives, Université de Nantes (UN)-IFR26-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre hospitalier universitaire de Nantes (CHU Nantes), This work was supported by the Région des Pays de la Loire (Program entitled 'Ciblage Moléculaire et Applications Thérapeutique') and the Agence Nationale de la Recherche 2007 Institut National de la Santé et de la Recherche Médicale Pathophysiology of Human Deseases Project No. R07196NS. L.D. has been supported by an Association pour la Recherche sur le Cancer postdoctoral fellowship

المصدر: Endocrinology
Endocrinology, Endocrine Society, 2008, 149 (7), pp.3688-97. ⟨10.1210/en.2007-1719⟩

مصطلحات موضوعية: Lipopolysaccharide Receptors, Gene Expression, Osteoclasts, MESH: Flow Cytometry, MESH: Monocytes, Monocytes, Mice, Endocrinology, MESH: Osteoclasts, MESH: Reverse Transcriptase Polymerase Chain Reaction, Serine, MESH: Animals, Phosphorylation, STAT3, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, CD11b Antigen, Receptor Activator of Nuclear Factor-kappa B, MESH: Antigens, CD14, Reverse Transcriptase Polymerase Chain Reaction, MESH: Bone Marrow Cells, MESH: STAT3 Transcription Factor, Cell Differentiation, Flow Cytometry, MESH: RANK Ligand, medicine.anatomical_structure, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, RANKL, MESH: Cell Differentiation, musculoskeletal diseases, STAT3 Transcription Factor, medicine.medical_specialty, MESH: Gene Expression, Blotting, Western, Bone Marrow Cells, Biology, Models, Biological, Cell Line, Osteoclast, Internal medicine, medicine, MESH: Blotting, Western, Animals, Humans, MESH: Serine, MESH: Mice, MESH: Humans, MESH: Phosphorylation, Activator (genetics), Interleukin-6, Macrophages, RANK Ligand, MESH: Antigens, CD11b, MESH: Models, Biological, MESH: Macrophages, MESH: Interleukin-6, MESH: Cell Line, MESH: Receptor Activator of Nuclear Factor-kappa B, STAT protein, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d95b27b9f58c81d24832c22006cba1fTest
https://pubmed.ncbi.nlm.nih.gov/18403479Test

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Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption

المؤلفون: Francois Lamoureux, Peggy Richard, Frédéric Blanchard, François Gouin, Séverine Battaglia, Françoise Rédini, Paul Pilet, Bruno Pitard, Dominique Heymann, Valérie Trichet, Yohann Wittrant

المصدر: Cancer research. 67(15)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05ab25984216ee5a93ea59e45a726b1Test
https://pubmed.ncbi.nlm.nih.gov/17671200Test

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