Study of Neurodevelopmental Outcome in Patients with Non-tumoral Hydrocephalus with Shunt Surgery Done in Infancy
| العنوان: | Study of Neurodevelopmental Outcome in Patients with Non-tumoral Hydrocephalus with Shunt Surgery Done in Infancy |
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| المؤلفون: | Naresh Biyani, Shilpa D Kulkarni, Sandeep Garg, Chandrashekhar E Deopujari |
| المصدر: | Journal of Pediatric Neurosciences |
| بيانات النشر: | Wolters Kluwer - Medknow, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, Neurology, Intelligence quotient, business.industry, neurodevelopmental outcome of pediatric hydrocephalus, General Neuroscience, Retrospective cohort study, Neurological disorder, medicine.disease, Infantile VP shunt outcome, Shunt (medical), Hydrocephalus, Pediatrics, Perinatology and Child Health, medicine, Etiology, pediatric hydrocephalus outcome, Outpatient clinic, Original Article, business |
| الوصف: | Background: Hydrocephalus (HC) is a common neurological disorder presenting in infancy, with a myriad of etiologies requiring early neurosurgical intervention. Objective: To study neurodevelopmental outcome in patients with HC with shunt surgery done in infancy. Materials and Methods: This was an observational retrospective cohort study of 50 pediatric patients (2 years to 16 years of age). These patients were diagnosed with HC and were operated on with ventriculo-peritoneal shunt (VP shunt) insertion in infancy (did not include patients with brain tumors) and then later following in the neurology outpatient department (OPD). Clinical records and neurodevelopmental assessment (intelligence quotient [IQ]/development quotient [DQ] and vision and hearing assessment) were reviewed. Results: Only 50% of the patients with congenital HC were diagnosed at birth, which included patients who had been diagnosed antenatally and they had lesser complications and better intellectual outcome (P = 0.12), compared with those who presented later with HC. Patient-related factors such as etiology of HC, antenatal diagnosis, and requirement of shunt revisions had poor correlation with neurodevelopmental outcome. Patients with late postoperative complications had significantly poor neurodevelopmental outcome (P ≤ 0.001). Patients with post-meningitis HC required a significantly higher number of shunt revisions than patients with other causes (P = 0.04). Conclusion: Better neurodevelopmental outcome depends on early diagnosis and early referral for the management than the cause of HC. Regular head circumference monitoring is the most feasible and sensitive screening tool for early pickup. Larger studies are needed for accurate prognostication. |
| اللغة: | English |
| تدمد: | 1998-3948 1817-1745 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9eb1f5a5fde76579dc9d88b8fbd180Test http://europepmc.org/articles/PMC8276960Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3d9eb1f5a5fde76579dc9d88b8fbd180 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19983948 18171745 |
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