-
1دورية أكاديمية
المؤلفون: Hall, Colton, Wolfe, Hannah, Wells, Alyssa, Chien, Huan-Chieh, Colas, Claire, Schlessinger, Avner, Giacomini, Kathleen M, Thomas, Allen A
المصدر: Bioorganic & Medicinal Chemistry Letters. 29(16)
مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Neurosciences, Antineoplastic Agents, Brain Diseases, Click Chemistry, Dose-Response Relationship, Drug, Histidine, Humans, Large Neutral Amino Acid-Transporter 1, Molecular Structure, Neoplasms, Prodrugs, Structure-Activity Relationship, Triazoles, Tryptophan, Membrane transporter, Solute carrier family, Triazole, Click chemistry, Amino acid, Cancer, Blood-brain barrier, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry, Organic chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/0m85s7h1Test
-
2دورية أكاديمية
المؤلفون: Chien, Huan-Chieh, Colas, Claire, Finke, Karissa, Springer, Seth, Stoner, Laura, Zur, Arik A, Venteicher, Brooklynn, Campbell, Jerome, Hall, Colton, Flint, Andrew, Augustyn, Evan, Hernandez, Christopher, Heeren, Nathan, Hansen, Logan, Anthony, Abby, Bauer, Justine, Fotiadis, Dimitrios, Schlessinger, Avner, Giacomini, Kathleen M, Thomas, Allen A
المصدر: Journal of Medicinal Chemistry. 61(16)
مصطلحات موضوعية: Neurosciences, Underpinning research, 1.1 Normal biological development and functioning, Cancer, Amino Acid Transport Systems, Antiporters, Escherichia coli Proteins, HEK293 Cells, Humans, Large Neutral Amino Acid-Transporter 1, Ligands, Molecular Docking Simulation, Phenylalanine, Stereoisomerism, Structural Homology, Protein, Structure-Activity Relationship, Substrate Specificity, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/5rr3f8h3Test
-
3دورية أكاديمية
المؤلفون: Chen, Eugene C, Khuri, Natalia, Liang, Xiaomin, Stecula, Adrian, Chien, Huan-Chieh, Yee, Sook Wah, Huang, Yong, Sali, Andrej, Giacomini, Kathleen M
المصدر: Journal of Medicinal Chemistry. 60(7)
مصطلحات موضوعية: Liver Disease, Digestive Diseases, Drug Discovery, HEK293 Cells, Humans, Ligands, Molecular Docking Simulation, Organic Cation Transporter 1, Small Molecule Libraries, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/6n89c7smTest
-
4دورية أكاديمية
المؤلفون: Zur, Arik A, Chien, Huan-Chieh, Augustyn, Evan, Flint, Andrew, Heeren, Nathan, Finke, Karissa, Hernandez, Christopher, Hansen, Logan, Miller, Sydney, Lin, Lawrence, Giacomini, Kathleen M, Colas, Claire, Schlessinger, Avner, Thomas, Allen A
المصدر: Bioorganic & Medicinal Chemistry Letters. 26(20)
مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Rare Diseases, Cancer, Orphan Drug, Blood-Brain Barrier, Carboxylic Acids, Chromatography, High Pressure Liquid, HEK293 Cells, Humans, Hydroxamic Acids, Large Neutral Amino Acid-Transporter 1, Magnetic Resonance Spectroscopy, Structure-Activity Relationship, SLC7A5, Amino acid, Acyl sulfonamide, Tetrazole, Transporter substrate, Transporter inhibitor, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry, Organic chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7cq4q8r0Test
-
5دورية أكاديمية
المؤلفون: Chen, Eugene C., Matsson, Pär, Azimi, Mina, Zhou, Xujia, Handin, Niklas, Yee, Sook Wah, Artursson, Per, Giacomini, Kathleen M.
المساهمون: National Institutes of Health, Swedish Research Council
المصدر: Pharmaceutical Research ; volume 39, issue 7, page 1599-1613 ; ISSN 0724-8741 1573-904X
مصطلحات موضوعية: Pharmacology (medical), Organic Chemistry, Pharmaceutical Science, Pharmacology, Molecular Medicine, Biotechnology
-
6دورية أكاديمية
المؤلفون: Augustyn, Evan, Finke, Karissa, Zur, Arik A, Hansen, Logan, Heeren, Nathan, Chien, Huan-Chieh, Lin, Lawrence, Giacomini, Kathleen M, Colas, Claire, Schlessinger, Avner, Thomas, Allen A
المصدر: Bioorganic & Medicinal Chemistry Letters. 26(11)
مصطلحات موضوعية: Organic Chemistry, Chemical Sciences, Cancer, Dose-Response Relationship, Drug, Humans, Large Neutral Amino Acid-Transporter 1, Models, Molecular, Molecular Structure, Phenylalanine, Structure-Activity Relationship, Tyrosine, SLC7A5, Amino acid, Negishi coupling, Transporter substrate, Transporter inhibitor, Medicinal and Biomolecular Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry, Organic chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/87g0x645Test
-
7دورية أكاديمية
المؤلفون: Wittwer, Matthias B, Zur, Arik A, Khuri, Natalia, Kido, Yasuto, Kosaka, Alan, Zhang, Xuexiang, Morrissey, Kari M, Sali, Andrej, Huang, Yong, Giacomini, Kathleen M
المصدر: Journal of Medicinal Chemistry. 56(3)
مصطلحات موضوعية: Biomedical and Clinical Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Clinical Research, Patient Safety, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Computer Simulation, Fluorescent Dyes, Organic Cation Transport Proteins, Prescription Drugs, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/72h384gnTest
-
8دورية أكاديمية
المصدر: Pharmaceutical Research ; volume 29, issue 9, page 2345-2353 ; ISSN 0724-8741 1573-904X
مصطلحات موضوعية: Pharmacology (medical), Organic Chemistry, Pharmaceutical Science, Pharmacology, Molecular Medicine, Biotechnology
-
9دورية أكاديمية
المؤلفون: Li, Shuanglian, Chen, Ying, Zhang, Shuzhong, More, Swati S., Huang, Xiaozhu, Giacomini, Kathleen M.
المصدر: Pharmaceutical Research ; volume 28, issue 3, page 610-625 ; ISSN 0724-8741 1573-904X
مصطلحات موضوعية: Pharmacology (medical), Organic Chemistry, Pharmaceutical Science, Pharmacology, Molecular Medicine, Biotechnology
-
10دورية أكاديمية
المؤلفون: Yee, Sook Wah, Stecula, Adrian, Chien, Huan-Chieh, Zou, Ling, Feofanova, Elena V., van Borselen, Marjolein, Cheung, Kit Wun Kathy, Yousri, Noha A., Suhre, Karsten, Kinchen, Jason M., Boerwinkle, Eric, Irannejad, Roshanak, Yu, Bing, Giacomini, Kathleen M.
المصدر: PLoS Genetics; 9/25/2019, Vol. 15 Issue 9, p1-38, 38p
مصطلحات موضوعية: STEROIDS, STEROID hormones, BILE acids, COMPUTATIONAL biology, NUCLEAR receptors (Biochemistry)