التفاصيل البيبلوغرافية
| العنوان: |
Organ Preservation in Rectal Cancer: An Overview of the Dutch Perspective and Recent Developments. |
| المؤلفون: |
Verrijssen, A.E.1 (AUTHOR) an-sofie.verrijssen@catharinaziekenhuis.nl, Ketelaers, S.H.J.2 (AUTHOR), Rutten, H.J.T.2 (AUTHOR), Theuws, J.1 (AUTHOR), Burger, J.W.A.2 (AUTHOR), Cnossen, J.S.1 (AUTHOR) |
| المصدر: |
Clinical Oncology. Feb2023, Vol. 35 Issue 2, p107-116. 10p. |
| مصطلحات موضوعية: |
*ATTITUDES of medical personnel, *CANCER relapse, *PRESERVATION of organs, tissues, etc., *PATIENTS' attitudes, *CHEMORADIOTHERAPY, *RECTUM, *COMBINED modality therapy, *RADIOISOTOPE brachytherapy, RECTUM tumors |
| مصطلحات جغرافية: |
NETHERLANDS |
| مستخلص: |
Although current guidelines on rectal cancer treatment often recommend rectal resection with or without neoadjuvant (chemo)radiotherapy, there is growing interest in organ-preserving treatment approaches among patients and clinicians in the Netherlands. Currently, multiple ongoing studies are investigating the value of different non-operative treatment modalities to improve tumour response rates and increase the chance of successful organ preservation. Papillon contact X-ray brachytherapy is a promising treatment modality to improve the chance of organ preservation, which seems especially relevant for elderly and frail patients unable or refusing to undergo total mesorectal excision surgery. The elderly and frail patient with rectal cancer poses a significant challenge and warrants a thorough multidisciplinary approach to provide the most optimal organ-preserving treatment. In this overview, an insight into the Dutch perspectives and developments within the field of organ preservation and the set-up of a Papillon facility to complete the spectrum of organ-preserving treatment options in a tertiary referral centre for rectal cancer treatment has been provided. • Within rectal cancer treatment, there is a growing interest in organ preserving treatment approaches among patients and clinicians. • A multidisciplinary approach is essential to optimise the organ preserving treatment of elderly and frail patients. • Contact X-ray brachytherapy seems a useful modality to improve the chance for successful organ preservation. • The addition of contact X-ray brachytherapy completes the spectrum of organ preserving treatment options in dedicated tertiary referral centres for rectal cancer treatment. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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