المؤلفون: Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Male, 0301 basic medicine, obesity, Medical Sciences, FGF21, Adipose tissue, Mice, 0302 clinical medicine, Weight loss, Homeostasis, Medicine, Multidisciplinary, biology, Middle Aged, Biological Sciences, Adipose Tissue, Female, Adiponectin, Antibody, medicine.symptom, FGF21 receptor activation, Adult, Agonist, medicine.medical_specialty, Adolescent, medicine.drug_class, 030209 endocrinology & metabolism, Antibodies, Food Preferences, Young Adult, 03 medical and health sciences, Internal medicine, Weight Loss, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, Aged, business.industry, Fibroblast growth factor receptor 1, Body Weight, medicine.disease, Obesity, Fibroblast Growth Factors, stomatognathic diseases, Macaca fascicularis, 030104 developmental biology, Endocrinology, biology.protein, food preference, business, metabolism, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18Test
https://doi.org/10.1073/pnas.2012073117Test

المؤلفون: Sharmila Rajan, Thomas Gelzleichter, Amos Baruch, Junichiro Sonoda, C. Andrew Boswell, Dale Stevens, Eric Stefanich, Danielle Mandikian, Kyra J. Cowan

المصدر: mAbs. 9:1379-1388

مصطلحات موضوعية: Male, 0301 basic medicine, Receptor complex, FGF21, medicine.drug_class, Receptor expression, Immunology, Drug Evaluation, Preclinical, Adipose tissue, CHO Cells, Pharmacology, Biology, Diet, High-Fat, Monoclonal antibody, 03 medical and health sciences, Cricetulus, Report, Cricetinae, medicine, Animals, Immunology and Allergy, Tissue Distribution, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Adiponectin, Fibroblast growth factor receptor 1, Antibodies, Monoclonal, Fibroblast Growth Factors, Mice, Inbred C57BL, Macaca fascicularis, 030104 developmental biology, Adipose Tissue, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe09bafc48ef65e54437fd42a8236afTest
https://doi.org/10.1080/19420862.2017.1373923Test

المؤلفون: Kyra J. Cowan, Feng Yang, Mark Z. Chen, Ambrose Williams, Terry Hudson, Shannon Liu, Nicole Valle, Timothy Tully, Junichiro Sonoda, Thomas Gelzleichter, Sharmila Rajan, Frank Macchi

المصدر: Journal of pharmacological and toxicological methods. 94(Pt 1)

مصطلحات موضوعية: 0301 basic medicine, Male, Bispecific antibody, Receptor complex, Mice, Obese, CHO Cells, Toxicology, Antibodies, Cell Line, 03 medical and health sciences, Mice, Cricetulus, Animals, Humans, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Related impurities, Obese Mice, Pharmacology, Manufacturing process, Chemistry, Membrane Proteins, Highly selective, Combinatorial chemistry, Mice, Inbred C57BL, Molecular Weight, stomatognathic diseases, Disease Models, Animal, Drug Combinations, 030104 developmental biology, HEK293 Cells, Product (mathematics), Immunoglobulin G, Drug product, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b66987db00744fc1e7acdc79bb85f9Test
https://pubmed.ncbi.nlm.nih.gov/29660397Test

المؤلفون: Diana Ronai Dunshee, Jose Zavala-Solorio, Hok Seon Kim, Sharmila Rajan, Yongmei Chen, James A. Ernst, Elizabeth Luis, Ai-Luen Wu, Robert Soriano, Ganesh Kolumam, Amos Baruch, Mark Z. Chen, Raymond K. Tong, Shelby K. Wyatt, Richard A.D. Carano, Christoph Spiess, Owen P. McGuinness, Jean-Michel Vernes, Andrew S. Peterson, Søren Warming, Keith R. Anderson, Xin Y. Rairdan, Junichiro Sonoda, Matthew J. Brauer, Scott Stawicki, Benjamin Haley, Laetitia Comps-Agrar, Jed Ross, Y. Gloria Meng, Johnny Gutierrez, James Ziai, Thomas Gelzleichter, Travis W. Bainbridge, Nicholas Lewin-Koh, Yan Wu, Nicholas van Bruggen, Vineela D. Gandham, Lance Kates, Yingnan Zhang, Dale Stevens

المصدر: EBioMedicine, Vol 2, Iss 7, Pp 730-743 (2015)
EBioMedicine

مصطلحات موضوعية: Male, FGF21, medicine.medical_treatment, Bispecific antibody, Adipose tissue, Mice, Obese, lcsh:Medicine, White adipose tissue, Brown adipose tissue, FGF19, Therapeutic antibody, Adipose Tissue, Brown, Antibodies, Bispecific, Insulin, Mice, Inbred BALB C, lcsh:R5-920, NASH, Thermogenesis, Type 2 diabetes, General Medicine, medicine.anatomical_structure, Original Article, Adipose tissue browning, Adiponectin, lcsh:Medicine (General), Protein Binding, medicine.medical_specialty, UCP1, Humanized antibody, Biology, General Biochemistry, Genetics and Molecular Biology, Cell Line, Insulin resistance, Internal medicine, Weight Loss, medicine, Animals, Humans, betaKlotho, Receptor, Fibroblast Growth Factor, Type 1, Obesity, Klotho Proteins, Fibroblast growth factor receptor 1, lcsh:R, Membrane Proteins, Hepatosteatosis, medicine.disease, Fibroblast Growth Factors, Mice, Inbred C57BL, Macaca fascicularis, Endocrinology, HEK293 Cells, FGFR1, Energy Metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292cc2ae94284197f1952ee9ad725380Test
http://www.sciencedirect.com/science/article/pii/S235239641530030XTest