دورية أكاديمية
Food-specific serum IgG and symptom reduction with a personalized, unrestricted-calorie diet of six weeks in Irritable Bowel Syndrome (IBS)
| العنوان: | Food-specific serum IgG and symptom reduction with a personalized, unrestricted-calorie diet of six weeks in Irritable Bowel Syndrome (IBS) |
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| المؤلفون: | Mattia Cappelletti, Emiliana Tognon, Linda Vona, Katia Basello, Andrea Costanzi, Michela Carola Speciani, Attilio Francesco Speciani |
| المصدر: | Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-6 (2020) |
| بيانات النشر: | BMC, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: | Irritable bowel syndrome, B-cell activating factor, Platelet activating factor, IgG, Nutrition, Diet, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: | Abstract Background Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life. Despite the prevalence of IBS, its etiology and pathophysiology are still to be fully understood, but immune response is known to be involved. In this study, we investigated the variation of two specific cytokines, B-cell activating factor (BAFF) and platelet-activating factor (PAF), the levels of food-specific IgG and the symptom severity, using Irritable Bowel Syndrome—Symptom Severity Score (IBS-SSS), following a personalized and unrestricted-calorie diet. Methods We enrolled 30 subjects with diagnosis of IBS, according to Rome-IV criteria, whose inflammatory markers were measured at baseline and after 6 weeks of dietary intervention. The subjects were monitored in a general practice outpatient setting and nutritional advice was offered remotely via two telephone sessions with a nutritionist. Results BAFF and PAF values did not differ between baseline and end of study, both in compliant (C) and non-compliant (NC) subjects. IgG levels significantly decreased only in compliant subjects: 37.32 (23.24–93.67) IU/mL; 27.9 (7.56–93.96) IU/mL (p = 0.02) and in non-compliant went from 51.83 (13.17–113.1) IU/mL to 44.06 (4.96–255.4) IU/mL (p = 0.97, ns). IBS-SSS significantly decreased in both compliant subjects, from 245 (110–480) to 110 (0–140) (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1743-7075 |
| العلاقة: | https://doaj.org/toc/1743-7075Test |
| DOI: | 10.1186/s12986-020-00528-x |
| الوصول الحر: | https://doaj.org/article/3e8167a6387e4421bf217548dc377519Test |
| رقم الانضمام: | edsdoj.3e8167a6387e4421bf217548dc377519 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17437075 |
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| DOI: | 10.1186/s12986-020-00528-x |