المؤلفون: Juri Rappsilber, Pablo Alcón, Lori A. Passmore, Shabih Shakeel, Zhuo A. Chen, Ketan J. Patel

المصدر: Alcón, P, Shakeel, S, Chen, Z A, Rappsilber, J, Patel, K J & Passmore, L A 2020, ' FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair ', Nature Structural and Molecular Biology, vol. 27, no. 3, pp. 240-248 . https://doi.org/10.1038/s41594-020-0380-1Test
Nature structural & molecular biology

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA damage, DNA repair, DNA-binding protein, Article, law.invention, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ubiquitin, Structural Biology, law, hemic and lymphatic diseases, FANCD2, Monoubiquitination, Molecular Biology, 030304 developmental biology, 0303 health sciences, biology, nutritional and metabolic diseases, Cell biology, chemistry, Recombinant DNA, biology.protein, 030217 neurology & neurosurgery, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dee59bf22e62e4f4da816000c77deeTest
https://www.pure.ed.ac.uk/ws/files/157669496/PMID32066963_AAM_Rappsilber.pdfTest

المؤلفون: Iván V. Rosado, Arno F. Alpi, Ketan J. Patel, Wojciech Niedzwiedz

المصدر: Nucleic Acids Research

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA Repair, DNA damage, DNA repair, Amino Acid Motifs, Sister chromatid exchange, Genome Integrity, Repair and Replication, Cell Line, Avian Proteins, hemic and lymphatic diseases, Genetics, Sister chromatids, Animals, Point Mutation, FANCM, Alleles, biology, Point mutation, Genetic Complementation Test, DNA Helicases, Helicase, nutritional and metabolic diseases, Fanconi Anemia Complementation Group Proteins, Protein Structure, Tertiary, Phenotype, biology.protein, Homologous recombination, Chickens, Sister Chromatid Exchange

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8583be9693540404083b4440cdd43201Test
https://ora.ox.ac.uk/objects/uuid:c03d9cc8-87ff-4f16-acb9-903e25d978dfTest

المؤلفون: Mark J. Arends, Iván V. Rosado, Frederic Langevin, Ketan J. Patel, Gerry P. Crossan

المصدر: Nature. 475:53-58

مصطلحات موضوعية: Cisplatin, congenital, hereditary, and neonatal diseases and abnormalities, Multidisciplinary, DNA damage, nutritional and metabolic diseases, DNA Repair Pathway, Biology, medicine.disease, medicine.disease_cause, Fanconi anemia, hemic and lymphatic diseases, FANCD2, Immunology, medicine, Cancer research, Carcinogen, Genotoxicity, medicine.drug, ALDH2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::302e8a07b6d4a5773946145b2b2b009cTest
https://doi.org/10.1038/nature10192Test

المؤلفون: Gerry P. Crossan, Mikko I. Kettunen, Frederic Langevin, Mark J. Arends, David Y. Lewis, Sanger Mouse Genetics, Iván V. Rosado, David J. Adams, Louise van der Weyden, Pierre-Henri L. Gaillard, Ferdia A. Gallagher, Ketan J. Patel, Kevin M. Brindle, Rebecca E. McIntyre

المساهمون: Medical Research Council, The Wellcome Trust Sanger Institute [Cambridge], Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Centre de Recherche en Cancérologie de Marseille (CRCM / U891 Inserm), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Cancer Research UK Cambridge Institute [Cambridge, Royaume-Uni] (CRUK), University of Cambridge [UK] (CAM), Addenbrooke's Hospital, Cambridge University NHS Trust

المصدر: Nature Genetics
Nature Genetics, Nature Publishing Group, 2011, 43 (2), pp.147-152. ⟨10.1038/ng.752⟩
Crossan, G P, van der Weyden, L, Rosado, I V, Langevin, F, Gaillard, P-H L, McIntyre, R E, Gallagher, F, Kettunen, M I, Lewis, D Y, Brindle, K, Arends, M J & Adams, D J & Patel, K J 2011, ' Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia ', Nature Genetics, vol. 43, no. 2, pp. 147-152 . https://doi.org/10.1038/ng.752Test
Nature genetics

مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, Fanconi anemia, complementation group C, DNA damage, Regulator, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Biology, Article, Recombinases, Mice, 03 medical and health sciences, 0302 clinical medicine, Fanconi anemia, hemic and lymphatic diseases, Genetics, medicine, Recombinase, Animals, Humans, Gene, Cellular Senescence, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Mice, Knockout, Phenocopy, 0303 health sciences, Genetic Complementation Test, nutritional and metabolic diseases, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.BBM.MN]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular Networks [q-bio.MN], Fibroblasts, Hematopoietic Stem Cells, medicine.disease, Magnetic Resonance Imaging, Cross-Linking Reagents, Fanconi Anemia, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, 030220 oncology & carcinogenesis, Female, Cell aging, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81175b7943a670092081f0bdd7fd2d8bTest
https://doi.org/10.1038/ng.752Test

المؤلفون: Frederic Langevin, Mioko Ohzeki, Laura J. Simpson, Julian E. Sale, Hendrik J. Kuiken, Wojciech Niedzwiedz, Ketan J. Patel, Minoru Takata, Paul E. Pace, Vibe H. Oestergaard

المصدر: Molecular Cell

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA Repair, DNA damage, DNA repair, PROTEINS, Mitomycin, Blotting, Western, Apoptosis, Biology, DNA polymerase delta, Article, hemic and lymphatic diseases, Proliferating Cell Nuclear Antigen, Endopeptidases, Monoubiquitination, Animals, Molecular Biology, Ubiquitin, Fanconi Anemia Complementation Group D2 Protein, Mutagenesis, Cell Cycle, Ubiquitination, nutritional and metabolic diseases, DNA, Cell Biology, Molecular biology, Chromatin, Proliferating cell nuclear antigen, Cross-Linking Reagents, Fanconi Anemia, Gene Expression Regulation, Gene Targeting, Mutation, biology.protein, Mutagenesis, Site-Directed, DNA mismatch repair, Ubiquitin-Specific Proteases, Cisplatin, Chickens, Protein Processing, Post-Translational, DNA Damage, Subcellular Fractions

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bfd5d03dd78296515fb680645a2b4aTest

المؤلفون: Mark S. Johnson, Wojciech Niedzwiedz, Paul E. Pace, Chong Yi Ong, Ketan J. Patel, Georgina Mosedale

المصدر: Molecular Cell. 15:607-620

مصطلحات موضوعية: DNA Replication, congenital, hereditary, and neonatal diseases and abnormalities, Fanconi anemia, complementation group C, DNA Repair, DNA damage, DNA repair, Recombinant Fusion Proteins, Cell Cycle Proteins, DNA-Directed DNA Polymerase, Biology, Cell Line, Chromosomal Instability, hemic and lymphatic diseases, FANCD2, Animals, Humans, FANCM, Molecular Biology, Recombination, Genetic, Genetics, Fanconi Anemia Complementation Group D2 Protein, X-Rays, FAN1, Fanconi Anemia Complementation Group C Protein, Nuclear Proteins, Proteins, nutritional and metabolic diseases, Epistasis, Genetic, DNA, Cell Biology, DNA repair protein XRCC4, Nucleotidyltransferases, Fanconi Anemia Complementation Group Proteins, DNA-Binding Proteins, Cross-Linking Reagents, Fanconi Anemia, Homologous recombination, Chickens, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f530c927d53cbf01b09a3cc6a94e682Test
https://doi.org/10.1016Test/j.molcel.2004.08.009

المؤلفون: Fanni Gergely, Donna L. Mallery, Chong Yi Ong, Kevin Hiom, Paul E. Pace, Ketan J. Patel, Cassandra J. Vandenberg

المصدر: Molecular Cell. 12(1):247-254

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, endocrine system diseases, DNA damage, Ubiquitin-Protein Ligases, Ubiquitin-conjugating enzyme, medicine.disease_cause, Ligases, hemic and lymphatic diseases, BARD1, Iron-Binding Proteins, FANCD2, medicine, Ring finger, Monoubiquitination, Animals, Humans, RNA, Small Interfering, skin and connective tissue diseases, Molecular Biology, Mutation, biology, Cell-Free System, BRCA1 Protein, Ubiquitin, Fanconi Anemia Complementation Group D2 Protein, Tumor Suppressor Proteins, nutritional and metabolic diseases, Nuclear Proteins, Cell Biology, Molecular biology, Ubiquitin ligase, Protein Structure, Tertiary, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Fanconi Anemia, Ubiquitin-Conjugating Enzymes, biology.protein, Carrier Proteins, DNA Damage, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d54a4604bac1b4a3daa92255850a11aTest

المؤلفون: Paul E. Pace, Georgina Mosedale, Johan P. de Winter, Fanni Gergely, Mark S. Johnson, Maureen E. Hoatlin, Ketan J. Patel, Hans Joenje, Wu Meng Tan, Chelvin C A Sng

المصدر: The EMBO journal. 21(13)

مصطلحات موضوعية: Cell Cycle Proteins, FANCE, FANCF, Fanconi anemia, FANCG, hemic and lymphatic diseases, Chlorocebus aethiops, Protein Interaction Mapping, Nuclear protein, Fanconi Anemia Complementation Group G Protein, General Neuroscience, Fanconi Anemia Complementation Group D2 Protein, Fanconi Anemia Complementation Group C Protein, Nuclear Proteins, RNA-Binding Proteins, Chromosome Breakage, Fanconi Anemia Complementation Group E Protein, Fanconi Anemia Complementation Group Proteins, DNA-Binding Proteins, COS Cells, Chromosome breakage, Protein Binding, congenital, hereditary, and neonatal diseases and abnormalities, Fanconi anemia, complementation group C, Macromolecular Substances, Recombinant Fusion Proteins, Active Transport, Cell Nucleus, Mutation, Missense, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, Fanconi Anemia Complementation Group F Protein, Structure-Activity Relationship, Bacterial Proteins, FANCD2, medicine, Animals, Humans, Molecular Biology, Cell Nucleus, General Immunology and Microbiology, nutritional and metabolic diseases, Proteins, medicine.disease, Molecular biology, Luminescent Proteins, Fanconi Anemia, Amino Acid Substitution, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad66d0e2b3b7f5a815ac6c0d6bba6790Test
https://pubmed.ncbi.nlm.nih.gov/12093742Test