المؤلفون: Chun Liang Chen, Tim H M Huang, Xiang Gu, Thu Minh Duong, Marieke Burleson, Haojie Huang, Yuqian Yan, Yi Zou, Michael A. Liss, Thomas G. Boyer, Lu-Zhe Sun, P. Renee Yew, Acarizia Easley, Addanki P. Kumar, Debodipta Das, Janice Jianhong Deng, Yi Chen, Tai Qin, Roble Bedolla

المصدر: Mol Cancer Res

مصطلحات موضوعية: Male, Cancer Research, animal structures, medicine.drug_class, Nerve Tissue Proteins, SPOP, Article, Mice, Prostate cancer, Castration Resistance, Zinc Finger Protein Gli3, Cell Line, Tumor, medicine, Animals, Humans, Sonic hedgehog, Molecular Biology, biology, business.industry, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, Gene signature, Androgen, medicine.disease, Repressor Proteins, Androgen receptor, Prostatic Neoplasms, Castration-Resistant, Oncology, Receptors, Androgen, Mutation, embryonic structures, biology.protein, Cancer research, Signal transduction, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ce740d5638259a84c2bc8945818a08Test
https://doi.org/10.1158/1541-7786.mcr-21-0108Test

المؤلفون: Medina, Ricardo F., Van Wijnen, Andre J., Stein, Gary S., Stein, Janet L.

المساهمون: Department of Cell Biology

المصدر: Biochemistry ; 45 ; 51 ; 15915-20

مصطلحات موضوعية: Cell Cycle, Cell Cycle Proteins, Cyclin E, Cyclin-Dependent Kinase 2, Half-Life, Hela Cells, Histones, Humans, Nuclear Proteins, Proteasome Endopeptidase Complex, RNA, Messenger, Repressor Proteins, Signal Transduction, Trans-Activators, Ubiquitin-Protein Ligase Complexes, Cell Biology

العلاقة: Link to Article in PubMed; http://dx.doi.org/10.1021/bi061425mTest; Biochemistry. 2006 Dec 26;45(51):15915-20. Link to article on publisher's site; 0006-2960 (Linking); http://hdl.handle.net/20.500.14038/49625Test; https://escholarship.umassmed.edu/stein/53Test; 1724093; stein/53

الإتاحة: https://doi.org/10.1021/bi061425mTest
https://doi.org/20.500.14038/49625Test
https://hdl.handle.net/20.500.14038/49625Test
https://escholarship.umassmed.edu/stein/53Test

المؤلفون: Bin Wang, Zhaohua Dai, Qian Gao, Yang Liu, Guoxiao Gu, Huixiao Zheng

المصدر: Biochemical and biophysical research communications. 594

مصطلحات موضوعية: Blood Glucose, Male, Inflammasomes, Ubiquitin-Protein Ligases, Biophysics, Down-Regulation, Kidney, Biochemistry, Streptozocin, Mice, Microscopy, Electron, Transmission, NLR Family, Pyrin Domain-Containing 3 Protein, Animals, Humans, Diabetic Nephropathies, Molecular Biology, Inflammation, Mice, Knockout, Podocytes, Ubiquitin, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, Cell Biology, Mice, Inbred C57BL, Repressor Proteins, HEK293 Cells, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5c1884de379abea40b5d0010430ac2Test
https://pubmed.ncbi.nlm.nih.gov/35081502Test

المؤلفون: Francesco Bertoni, Steven A. Carr, Manuela Cavalli, Holger Moch, Anna Rinaldi, Arianna Vallerga, Azzurra Mutti, Tanya Svinkina, Ze Dong, Hana Janouskova, Geniver El Tekle, Tiziano Bernasocchi, Simon Linder, Giuseppina M. Carbone, Daniela Bossi, Marianna Kruithof-de Julio, Roger Geiger, Laura P. Brandt, Wilbert Zwart, Andrea Rinaldi, Simone Mosole, Marita Zoma, Marco Bolis, Jean-Philippe Theurillat, Filippo Spriano, Andrea Alimonti, Peter Schraml, Cai-Guang Yang, Domenico Albino, Valentina Ceserani, Namrata D. Udeshi, Mark A. Rubin

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Bernasocchi, Tiziano; El Tekle, Geniver; Bolis, Marco; Mutti, Azzurra; Vallerga, Arianna; Brandt, Laura P.; Spriano, Filippo; Svinkina, Tanya; Zoma, Marita; Ceserani, Valentina; Rinaldi, Anna; Janouskova, Hana; Bossi, Daniela; Cavalli, Manuela; Mosole, Simone; Geiger, Roger; Dong, Ze; Yang, Cai-Guang; Albino, Domenico; Rinaldi, Andrea; ... (2021). Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer. Nature communications, 12(1), p. 734. Nature Publishing Group 10.1038/s41467-020-20820-x <http://dx.doi.org/10.1038/s41467-020-20820-xTest>
Nature Communications, 12

مصطلحات موضوعية: Proteomics, Male, Cancer therapy, medicine.drug_class, Science, Mice, Nude, 610 Medicine & health, Cell Cycle Proteins, SPOP, medicine.disease_cause, Article, Tumour biomarkers, Prostate cancer, Mice, Transcriptional Regulator ERG, Cell Line, Tumor, medicine, Biomarkers, Tumor, Animals, Humans, Immunoprecipitation, Transcription factor, Cancer genetics, Oncogene Proteins, biology, Nuclear Proteins, Prostatic Neoplasms, Ubiquitin-Protein Ligase Complexes, medicine.disease, Androgen, Immunohistochemistry, Ubiquitin ligase, Androgen receptor, DNA-Binding Proteins, Repressor Proteins, HEK293 Cells, Androgen Therapy, Receptors, Androgen, Mutation, biology.protein, Cancer research, Carcinogenesis, 610 Medizin und Gesundheit, Co-Repressor Proteins, Protein Binding, Signal Transduction

وصف الملف: application/pdf; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe8919843ab06744fd7a44c9ed8c87aTest

المؤلفون: Fuminori Tokunaga, Ayumi Shintani, Daijiro Kabata, Hirohisa Miyashita, Daisuke Oikawa, Seigo Terawaki

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Programmed cell death, Immunology, Apoptosis, Hydrocarbons, Aromatic, NF-κB, 03 medical and health sciences, chemistry.chemical_compound, Ubiquitin, Interferon, xenophagy, Macroautophagy, ubiquitin, LUBAC, medicine, Xenophagy, NDP52, Immunology and Allergy, Humans, Enzyme Inhibitors, Original Research, Innate immune system, 030102 biochemistry & molecular biology, biology, Tumor Necrosis Factor-alpha, Intrinsic apoptosis, NF-kappa B, Ubiquitination, Nuclear Proteins, Salmonella enterica, Ubiquitin-Protein Ligase Complexes, Immunity, Innate, Cell biology, Crosstalk (biology), 030104 developmental biology, HEK293 Cells, chemistry, A549 Cells, biology.protein, lcsh:RC581-607, medicine.drug, HeLa Cells, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1757ce3e853caa5adcb2baca5dc501Test
https://pubmed.ncbi.nlm.nih.gov/33815386Test

المؤلفون: Hongchen Cai, Aimin Liu

المصدر: Proceedings of the National Academy of Sciences. 113:14751-14756

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, Patched, Heterozygote, animal structures, Indian hedgehog, Ubiquitin-Protein Ligases, Kruppel-Like Transcription Factors, Nerve Tissue Proteins, Biology, SPOP, Bone and Bones, Mice, 03 medical and health sciences, Chondrocytes, Genes, Reporter, Zinc Finger Protein Gli3, GLI2, GLI3, Animals, Hedgehog Proteins, Hedgehog, Crosses, Genetic, Multidisciplinary, Gene Expression Regulation, Developmental, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, Cell Differentiation, Biological Sciences, biology.organism_classification, Cell biology, Ubiquitin ligase, Repressor Proteins, body regions, 030104 developmental biology, Lac Operon, Ubiquitin ligase complex, embryonic structures, biology.protein, Osteoporosis, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4da081d0789d93a175fad62b9ac9efTest
https://doi.org/10.1073/pnas.1612520114Test

المؤلفون: Torsten Hartwig, Sebastian Kupka, Helena Draberova, Matthias Reichert, Lucia Taraborrelli, Eva Rieser, Elodie Lafont, Henning Walczak, Diego de Miguel, Peter Draber, Katrin Rittinger, Lisanne Spilgies, Luigi Martino, Silvia Surinova

المصدر: Cell Reports
Cell Reports, Vol 13, Iss 10, Pp 2258-2272 (2015)

مصطلحات موضوعية: Transcriptional Activation, Tumor suppressor gene, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Deubiquitinating enzyme, Ubiquitin, Transduction, Genetic, immune system diseases, hemic and lymphatic diseases, Humans, Immunoprecipitation, lcsh:QH301-705.5, Tumor Necrosis Factor alpha-Induced Protein 3, Regulation of gene expression, Innate immune system, Cell Death, biology, Tumor Suppressor Proteins, Intracellular Signaling Peptides and Proteins, Ubiquitination, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, Deubiquitinating Enzyme CYLD, 3. Good health, Cell biology, DNA-Binding Proteins, lcsh:Biology (General), biology.protein, Signal transduction, Signal Transduction, Deubiquitination

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0eeab16ff3b54ecc6463e1bfb0a77fTest
https://doi.org/10.1016/j.celrep.2015.11.009Test

المؤلفون: Amina Zoubeidi, Martin E. Gleave

المصدر: EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
EMBO Molecular Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Medicine (General), Genotype, Blotting, Western, Phenylenediamines, QH426-470, Biology, Histone Deacetylases, Mice, 03 medical and health sciences, Prostate cancer, R5-920, 0302 clinical medicine, Genetics, medicine, Animals, Humans, Immunoprecipitation, News & Views, Pharmacology & Drug Discovery, Protein kinase B, PI3K/AKT/mTOR pathway, Cancer, Mice, Knockout, Acrylamides, Activator (genetics), TOR Serine-Threonine Kinases, PTEN Phosphohydrolase, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, medicine.disease, HDAC3, Molecular medicine, Repressor Proteins, Androgen receptor, HEK293 Cells, 030104 developmental biology, Receptors, Androgen, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Signal transduction, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac2eb55281872036bca2ab9e8d270d9Test
https://doi.org/10.15252/emmm.201808928Test

المؤلفون: Hongchen Cai, Aimin Liu

المصدر: Developmental biology. 432(1)

مصطلحات موضوعية: 0301 basic medicine, animal structures, Nerve Tissue Proteins, SPOP, Zinc Finger Protein Gli2, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Neural Stem Cells, GLI1, Interneurons, Zinc Finger Protein Gli3, GLI2, GLI3, medicine, Animals, Hedgehog Proteins, Sonic hedgehog, Molecular Biology, Floor plate, Body Patterning, biology, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, Cell Differentiation, Cell Biology, Spinal cord, Repressor Proteins, 030104 developmental biology, medicine.anatomical_structure, Spinal Cord, embryonic structures, Mutation, Cancer research, biology.protein, Trans-Activators, Spinal cord patterning, 030217 neurology & neurosurgery, Developmental Biology, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f7db1194548affc667793ba65a6889Test
https://pubmed.ncbi.nlm.nih.gov/28412462Test

المؤلفون: Chen Zhang, Zhengchang Liu, Melissa S. Overstreet, Sylvester Tumusiime

المصدر: Journal of Biological Chemistry. 286:4620-4631

مصطلحات موضوعية: Cytoplasm, Saccharomyces cerevisiae Proteins, Ubiquitin-Protein Ligases, Saccharomyces cerevisiae, Biochemistry, Anaphase-Promoting Complex-Cyclosome, Gene Expression Regulation, Fungal, Extracellular, Cell division control protein 4, Amino Acids, Molecular Biology, Transcription factor, Cellular localization, chemistry.chemical_classification, biology, F-Box Proteins, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Nuclear Proteins, RNA-Binding Proteins, Ubiquitin-Protein Ligase Complexes, Cell Biology, Protein Structure, Tertiary, Ubiquitin ligase, Amino acid, Cell biology, DNA-Binding Proteins, chemistry, Ubiquitin-Conjugating Enzymes, biology.protein, Serine Proteases, Carrier Proteins, Nuclear localization sequence, Transcription Factors, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04015301d7e5560c9bc4733ee1edc8cdTest
https://doi.org/10.1074/jbc.m110.195313Test