دورية أكاديمية
Post-COVID-19 vaccination inflammatory syndrome: A case report
| العنوان: | Post-COVID-19 vaccination inflammatory syndrome: A case report |
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| المؤلفون: | Durucan I., Guner S., Kilickiran Avci B., Unverengil G., Melikoglu M., Ugurlu S. |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | BNT162b2, COVID-19, myocarditis, myositis, vaccine, alanine aminotransferase, aspartate aminotransferase, bnt 162b 2, C reactive protein, creatine kinase, creatinine, lactate dehydrogenase, metoprolol, muscle relaxant agent, nonsteroid antiinflammatory agent, prednisolone, ramipril, spironolactone, steroid, tozinameran, troponin T, abnormal urine composition, adult, alanine aminotransferase blood level, Article, aspartate aminotransferase blood level, body weight loss, burning sensation, case report, clinical article |
| الوصف: | A previously healthy 24-year-old male patient was referred to our clinic with bilateral lower extremity pain and dark urine, which were developed 2 weeks after receiving the second dose of the BNT162b2 vaccine against severe acute respiratory coronavirus 2. Laboratory tests indicated rhabdomyolysis. Lower extremity magnetic resonance imaging was compatible with myositis. Myositis-related antibodies were negative. Biopsy taken from gastrocnemius muscle revealed muscle necrosis and striking expression of major histocompatibility complex class I antigen. He was successfully treated, and his complaints were resolved. One week later at follow-up, he reported new-onset exertional dyspnoea with palpitations. ST-segment depressions were spotted on electrocardiography. Troponin T was found elevated as 0.595 ng/ml (normal <0.014 ng/ml). Echocardiography showed a hypokinetic left ventricle with an ejection fraction of 40% and pericardial effusion of 2 mm. An appropriate treatment plan was formulated for the diagnosis of myocarditis, eventually, the patient recovered within 10 days. The BNT162b2 messenger ribonucleic acid (mRNA) vaccine was felt to cause the aforementioned condition since no other aetiology could be identified. Although it is known that BNT162b2 may induce myocarditis, myositis concomitant myocarditis appears to be a very rare adverse effect of this vaccine. © 2022 Japan College of Rheumatology. Published by Oxford University Press. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 24725625 |
| العلاقة: | Modern Rheumatology Case Reports; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.1093/mrcr/rxac041Test; https://hdl.handle.net/20.500.12831/19693Test; 280; 282; 2-s2.0-85146735444 |
| DOI: | 10.1093/mrcr/rxac041 |
| الإتاحة: | https://doi.org/10.1093/mrcr/rxac041Test https://doi.org/20.500.12831/19693Test https://hdl.handle.net/20.500.12831/19693Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.4B5F5DD |
| قاعدة البيانات: | BASE |
| تدمد: | 24725625 |
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| DOI: | 10.1093/mrcr/rxac041 |