التفاصيل البيبلوغرافية
| العنوان: |
Radiogenomics and Its Role in Lymphoma. |
| المؤلفون: |
Khan, Saman, Naim, Sohaib, Bilwani, Rania, Salem, Amirah, Gorlin, David, Muhammad, Ahmad, Gul, Maryam, Imam, Muhammad H., Chaudhry, Ammar |
| المصدر: |
Current Hematologic Malignancy Reports; Jun2020, Vol. 15 Issue 3, p211-224, 14p |
| مستخلص: |
Purpose of Review: Imaging features of lymphoma vary regionally. Awareness of site-specific key imaging characteristics of lymphoma can aid in rapid staging and assist in prompt treatment. FDG PET/CT and conventional MRI are readily available diagnostic modalities with excellent sensitivity and good specificity. Diagnostic specificity can be enhanced using emerging PET radiotracers, e.g., FLT and FET. Recent Findings: Emerging research has shown higher dimensional analysis (radiomics and radiogenomics) of imaging data can yield information of the underlying genetic aberrations in lymphoma, which can aid in assessing real-time evolution of tumor. Summary: CT, PET/CT, MRI, and ultrasound accentuate the intrinsic qualities of lymphoma (e.g., FDG PET/CT for increased metabolic activity, FLT PET/CT for increased proliferation index, and DWI for increased cellularity) and play an essential role in its diagnosis and examination. Advanced radiogenomic analyses use radiomic parameters to deduce genetic variations of lymphoma, providing noninvasive, repeatable, and real-time surveillance of its genetic progression. [ABSTRACT FROM AUTHOR] |
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Copyright of Current Hematologic Malignancy Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
