دورية أكاديمية
Protein S-nitrosylation in photosynthetic organisms: A comprehensive overview with future perspectives
| العنوان: | Protein S-nitrosylation in photosynthetic organisms: A comprehensive overview with future perspectives |
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| المؤلفون: | ZAFFAGNINI, MIRKO, De Mia, M., Morisse, S., Di Giacinto, N., Marchand, C. H., Maes, A., Lemaire, S. D, TROST, PAOLO BERNARDO |
| المساهمون: | Zaffagnini, Mirko, De Mia, M., Morisse, S., Di Giacinto, N., Marchand, C. H., Maes, A., Lemaire, S. D, Trost, PAOLO BERNARDO |
| سنة النشر: | 2016 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | Cysteine, Denitrosylation, Nitric oxide, Nitrosothiol, Redox signaling, S-nitrosylation, Biochemistry, Biophysic, Analytical Chemistry, Molecular Biology |
| الوصف: | Background The free radical nitric oxide (NO) and derivative reactive nitrogen species (RNS) play essential roles in cellular redox regulation mainly through protein S-nitrosylation, a redox post-translational modification in which specific cysteines are converted to nitrosothiols. Scope of view This review aims to discuss the current state of knowledge, as well as future perspectives, regarding protein S-nitrosylation in photosynthetic organisms. Major conclusions NO, synthesized by plants from different sources (nitrite, arginine), provides directly or indirectly the nitroso moiety of nitrosothiols. Biosynthesis, reactivity and scavenging systems of NO/RNS, determine the NO-based signaling including the rate of protein nitrosylation. Denitrosylation reactions compete with nitrosylation in setting the levels of nitrosylated proteins in vivo. General significance Based on a combination of proteomic, biochemical and genetic approaches, protein nitrosylation is emerging as a pervasive player in cell signaling networks. Specificity of protein nitrosylation and integration among different post-translational modifications are among the major challenges for future experimental studies in the redox biology field. This article is part of a Special Issue entitled: Plant Proteomics — a bridge between fundamental processes and crop production, edited by Dr. Hans-Peter Mock. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/26861774; info:eu-repo/semantics/altIdentifier/wos/WOS:000379276000008; volume:1864; issue:8; firstpage:952; lastpage:966; numberofpages:15; journal:BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS; http://hdl.handle.net/11585/559693Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84975742792; http://www.elsevier.com/locate/bbapapTest |
| DOI: | 10.1016/j.bbapap.2016.02.006 |
| الإتاحة: | https://doi.org/10.1016/j.bbapap.2016.02.006Test http://hdl.handle.net/11585/559693Test http://www.elsevier.com/locate/bbapapTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.14646BA4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.bbapap.2016.02.006 |
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