التفاصيل البيبلوغرافية
| العنوان: |
MPGN type I induced by granulocyte colony stimulating factor. |
| المؤلفون: |
Magen, D., Mandel, Hana, Berant, Moshe, Ben-Izhak, Ofer, Zelikovic, Israel |
| المصدر: |
Pediatric Nephrology. May2002, Vol. 17 Issue 5, p370. 3p. |
| مصطلحات موضوعية: |
*NEUTROPENIA, *GRANULOCYTE-colony stimulating factor, *GLOMERULONEPHRITIS |
| مستخلص: |
We report a girl with severe congenital neutropenia who has received long-term granulocyte-colony stimulating factor (G-CSF) therapy and has developed macroscopic hematuria, proteinuria, and decreased renal function associated with biopsy-proven membranoproliferative glomerulonephritis (MPGN) type I. Temporary discontinuation of G-CSF therapy as well as the use of glycosylated G-CSF has resulted in improvement in renal manifestations. We postulate that the MPGN was G-CSF- induced. Long-term G-CSF therapy should be used with great caution and close surveillance of kidney function. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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