نتائج البحث - "Hiromu Okano"

1

Oral Exposure to Lead Acetate for 28 Days Reduces the Number of Neural Progenitor Cells but Increases the Number and Synaptic Plasticity of Newborn Granule Cells in Adult Hippocampal Neurogenesis of Young-Adult Rats

المؤلفون: Natsuno Maeda, Saori Shimizu, Yasunori Takahashi, Reiji Kubota, Suzuka Uomoto, Keisuke Takesue, Kazumi Takashima, Hiromu Okano, Ryota Ojiro, Shunsuke Ozawa, Qian Tang, Meilan Jin, Yoshiaki Ikarashi, Toshinori Yoshida, Makoto Shibutani

المصدر: Neurotoxicity Research. 40:2203-2220

مصطلحات موضوعية: Neuronal Plasticity, Brain-Derived Neurotrophic Factor, Neurogenesis, General Neuroscience, Apoptosis, Toxicology, Hippocampus, Rats, Rats, Sprague-Dawley, Lead, Neural Stem Cells, Prenatal Exposure Delayed Effects, Neuroinflammatory Diseases, Dentate Gyrus, Animals, Humans, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df42f339db27e6e37d880be11e2e84d2Test
https://doi.org/10.1007/s12640-022-00577-5Test

2

Continuous Exposure to Alpha-Glycosyl Isoquercitrin from Gestation Ameliorates Disrupted Hippocampal Neurogenesis in Rats Induced by Gestational Injection of Valproic Acid

المؤلفون: Kazumi Takashima, Hiromu Okano, Ryota Ojiro, Qian Tang, Yasunori Takahashi, Shunsuke Ozawa, Xinyu Zou, Mihoko Koyanagi, Robert R. Maronpot, Toshinori Yoshida, Makoto Shibutani

المصدر: Neurotoxicity Research. 40:2278-2296

مصطلحات موضوعية: Autism Spectrum Disorder, Valproic Acid, Neurogenesis, General Neuroscience, Toxicology, Hippocampus, Antioxidants, Rats, Pregnancy, Prenatal Exposure Delayed Effects, Humans, Animals, Female, Ciliary Neurotrophic Factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ef35d9d6db74e63e76f56d79c21179Test
https://doi.org/10.1007/s12640-022-00574-8Test

3

Oral exposure to high-dose ethanol for 28 days in rats reduces neural stem cells and immediate nascent neural progenitor cells as well as FOS-expressing newborn granule cells in adult hippocampal neurogenesis

المؤلفون: Yasunori Takahashi, Hiromu Okano, Kazumi Takashima, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutani

المصدر: Toxicology Letters. 360:20-32

مصطلحات موضوعية: Rats, Sprague-Dawley, Ethanol, Neural Stem Cells, Pregnancy, Neurogenesis, Prenatal Exposure Delayed Effects, Dentate Gyrus, Animals, Female, General Medicine, Toxicology, Hippocampus, Rats

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b1d81a9bb2ab35f4ad8a2409409b15Test
https://doi.org/10.1016/j.toxlet.2022.02.006Test

4

Oral exposure to aluminum chloride for 28 days suppresses neural stem cell proliferation and increases mature granule cells in adult hippocampal neurogenesis of young‐adult rats

المؤلفون: Saori Shimizu, Natsuno Maeda, Yasunori Takahashi, Suzuka Uomoto, Keisuke Takesue, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Hiromu Okano, Kazumi Takashima, Gye‐Hyeong Woo, Toshinori Yoshida, Makoto Shibutani

المصدر: Journal of Applied Toxicology. 42:1337-1353

مصطلحات موضوعية: Rats, Sprague-Dawley, Mice, Neural Stem Cells, Neurogenesis, Dentate Gyrus, Aluminum Chloride, Animals, Toxicology, Hippocampus, Cell Proliferation, Rats

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f7dda9b20ae3085f415d9166d619cdTest
https://doi.org/10.1002/jat.4299Test

5

Gene expression profiles of multiple brain regions in rats differ between developmental and postpubertal exposure to valproic acid

المؤلفون: Meilan Jin, Kazumi Takashima, Ryota Ojiro, Toshinori Yoshida, Hiromu Okano, Yumi Akahori, Qian Tang, Shunsuke Ozawa, Yousuke Watanabe, Yasunori Takahashi, Fumiyo Saito, Makoto Shibutani

المصدر: Journal of Applied Toxicology. 42:864-882

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036b896b16efd2e224f99ff6bcacddfcTest
https://doi.org/10.1002/jat.4263Test

6

Ameliorating effect of continuous alpha-glycosyl isoquercitrin treatment starting from late gestation in a rat autism model induced by postnatal injection of lipopolysaccharides

المؤلفون: Hiromu Okano, Kazumi Takashima, Yasunori Takahashi, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Mihoko Koyanagi, Robert R. Maronpot, Toshinori Yoshida, Makoto Shibutani

المصدر: Chemico-biological interactions. 351

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b08141abd1de14715cee3f8e2e2d353Test
https://pubmed.ncbi.nlm.nih.gov/34863679Test

7

Disruption of postnatal neurogenesis and adult-stage suppression of synaptic plasticity in the hippocampal dentate gyrus after developmental exposure to sterigmatocystin in rats

المؤلفون: Qian Tang, Kota Nakajima, Saori Shimizu, Shunsuke Ozawa, Tomoya Yoshinari, Makoto Shibutani, Kazumi Takashima, Hiromu Okano, Toshinori Yoshida, Meilan Jin, Yoshiko Sugita-Konishi, Yasunori Takahashi, Ryota Ojiro

المصدر: Toxicology letters. 349

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Interneuron, Neurogenesis, Sterigmatocystin, Apoptosis, Weaning, Hippocampal formation, Biology, Toxicology, Subgranular zone, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Neural Stem Cells, Internal medicine, medicine, Animals, DNA Breaks, Double-Stranded, Cell Proliferation, No-Observed-Adverse-Effect Level, Arc (protein), Neuronal Plasticity, Dose-Response Relationship, Drug, Dentate gyrus, General Medicine, Receptors, Neurotransmitter, Oxidative Stress, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Gene Expression Regulation, Synaptic plasticity, Dentate Gyrus, NMDA receptor, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38da65b0dda76b2299c170bc2fa31adTest
https://pubmed.ncbi.nlm.nih.gov/34126181Test

8

Identification of gene targets of developmental neurotoxicity focusing on DNA hypermethylation involved in irreversible disruption of hippocampal neurogenesis in rats

المؤلفون: Makoto Shibutani, Gyeâ€Hyeong Woo, Satomi Kikuchi, Yasunori Takahashi, Qian Tang, Hiromu Okano, Kazumi Takashima, Ryota Ojiro, Toshinori Yoshida

المصدر: Journal of Applied Toxicology

مصطلحات موضوعية: Male, Propanols, glycidol (GLY), 010501 environmental sciences, Hippocampal formation, Toxicology, 01 natural sciences, Hippocampus, Pregnancy, rat, Research Articles, Neurons, 0303 health sciences, Arc (protein), Neuronal Plasticity, valproic acid (VPA), Neurogenesis, Gene Expression Regulation, Developmental, 6‐propyl‐2‐thiouracil (PTU), Maternal Exposure, Prenatal Exposure Delayed Effects, developmental neurotoxicity (DNT), Female, Neurotoxicity Syndromes, Research Article, medicine.medical_specialty, endocrine system, Offspring, Biology, CREB, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, medicine, Animals, Humans, 030304 developmental biology, 0105 earth and related environmental sciences, Dentate gyrus, DNA, DNA Methylation, hippocampal neurogenesis, Rats, Endocrinology, Propylthiouracil, Synaptic plasticity, Dentate Gyrus, biology.protein, gene expression, Epoxy Compounds, methylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa5082abdaaa905ef092e4f7a6be63bTest
https://pubmed.ncbi.nlm.nih.gov/33150595Test

9

Aberrant neurogenesis and late onset suppression of synaptic plasticity as well as sustained neuroinflammation in the hippocampal dentate gyrus after developmental exposure to ethanol in rats

المؤلفون: Yasunori Takahashi, Kazumi Takashima, Toshinori Yoshida, Makoto Shibutani, Shunsuke Ozawa, Ryota Ojiro, Hiromu Okano, Qian Tang, Bunichiro Ogawa, Risako Yamashita, Gye-Hyeong Woo

المصدر: Toxicology. 462:152958

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fca09c58b400e2e734c75966d1fa26bTest
https://doi.org/10.1016/j.tox.2021.152958Test

10

Induction of cellular senescence as a late effect and BDNF-TrkB signaling-mediated ameliorating effect on disruption of hippocampal neurogenesis after developmental exposure to lead acetate in rats

المؤلفون: Kazumi Takashima, Risako Yamashita, Ryota Ojiro, Mio Kobayashi, Reiji Kubota, Makoto Shibutani, Satomi Kikuchi, Yasunori Takahashi, Yoshiaki Ikarashi, Qian Tang, Toshinori Yoshida, Hiromu Okano, Bunichiro Ogawa, Meilan Jin

المصدر: Toxicology. 456:152782

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09163ba89d006878182e069956eea414Test
https://doi.org/10.1016/j.tox.2021.152782Test

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