المؤلفون: Rachel Lasry, Adina Maria Palhegyi, Timothy Barrett, Congxin Sun, Malkiel A. Cohen, Surbhi Verma, Yosef Buganim, Moriyah Naama, Tatiana R. Rosenstock, Sovan Sarkar, Dhiraj Kumar, Elena Seranova, Simona Dimova

المصدر: Journal of Molecular Biology. 432:2754-2798

مصطلحات موضوعية: Cell type, Induced Pluripotent Stem Cells, Biology, Models, Biological, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Autophagy, medicine, Animals, Humans, Induced pluripotent stem cell, Molecular Biology, Tissue homeostasis, 030304 developmental biology, Neurons, 0303 health sciences, Drug discovery, Neurodegeneration, Cell Differentiation, Neurodegenerative Diseases, Cellular Reprogramming, medicine.disease, 3. Good health, Stem cell, Neuroscience, Reprogramming, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd642c610fa0f8d523ce20962b754631Test
https://doi.org/10.1016/j.jmb.2020.01.024Test

المؤلفون: Congxin Sun, Sovan Sarkar, Tatiana R. Rosenstock, Malkiel A. Cohen

المصدر: Methods in Molecular Biology ISBN: 9781071625842

مصطلحات موضوعية: Autophagosome, medicine.anatomical_structure, Drug discovery, Autophagy, Neurodegeneration, Cell, medicine, Cellular homeostasis, Biology, medicine.disease, Intracellular, Energy homeostasis, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6b43e0447deaa930d7156fff7815f8dbTest
https://doi.org/10.1007/7651_2021_420Test

المؤلفون: Luiz Felipe Souza E Silva, Miruna Chipara, Amanda Siena, Mariana Dutra Brito, Sovan Sarkar, Tatiana R. Rosenstock

المصدر: Toxicity Assessment ISBN: 9781071610909

مصطلحات موضوعية: 0301 basic medicine, Chemistry, Neurodegeneration, chemistry.chemical_element, Metabolism, Cell fate determination, Mitochondrion, medicine.disease, Oxygen, Neuroprotection, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cell culture, medicine, 030217 neurology & neurosurgery, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::142a5351a9f95518e98c6ba83bf26888Test
https://doi.org/10.1007/978-1-0716-1091-6_15Test

المؤلفون: Qing Gao, Dorothea Maetzel, Rudolf Jaenisch, Albert W. Cheng, Maisam Mitalipova, Sovan Sarkar, Lina Abi-Mosleh, Ping Xu, Haoyi Wang

المساهمون: Massachusetts Institute of Technology. Department of Biology, Whitehead Institute for Biomedical Research, Maetzel, Dorothea, Sarkar, Sovan, Wang, Haoyi, Xu, Ping, Cheng, Albert W., Gao, Qing, Mitalipova, Maisam, Jaenisch, Rudolf

المصدر: Stem Cell Reports, Vol 2, Iss 6, Pp 866-880 (2014)
Stem Cell Reports
Elsevier

مصطلحات موضوعية: Adult, medicine.medical_specialty, Cell type, Lipid storage disorder, Induced Pluripotent Stem Cells, Biology, Biochemistry, Article, Internal medicine, Genetics, medicine, Autophagy, Humans, Viability assay, Induced pluripotent stem cell, Child, lcsh:QH301-705.5, Cells, Cultured, Neurons, lcsh:R5-920, Niemann–Pick disease, type C, Neurodegeneration, Niemann-Pick Disease, Type C, Cell Biology, medicine.disease, 3. Good health, Endocrinology, Cholesterol, lcsh:Biology (General), Child, Preschool, Cancer research, Hepatocytes, NPC1, lcsh:Medicine (General), Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3b92af7541ac0603677a70b275bf39Test

المؤلفون: Sovan Sarkar

المصدر: Biochemical Society Transactions. 41:1103-1130

مصطلحات موضوعية: Cell Survival, TOR Serine-Threonine Kinases, Transgene, medicine.medical_treatment, Neurodegeneration, Autophagy, Neurodegenerative Diseases, Drug action, Biology, medicine.disease, Biochemistry, Cell biology, Targeted therapy, Small Molecule Libraries, Cytosol, medicine, Humans, Molecular Targeted Therapy, PI3K/AKT/mTOR pathway, Signal Transduction, Calcium signaling

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3262b36fdca0f00fb5027319d7be3d3bTest
https://doi.org/10.1042/bst20130134Test

المؤلفون: Sara Imarisio, Sovan Sarkar, Andrea Williams, Guido Kroemer, Maurizio Renna, Angeleen Fleming, Cahir J. O'Kane, David C. Rubinsztein, Claudia Rose, Viktor I. Korolchuk, Shouqing Luo, Moisés García-Arencibia, Benjamin R. Underwood

المساهمون: Fleming, Angeleen [0000-0003-3721-7126], Underwood, Benjamin [0000-0003-3427-9487], O'Kane, Cahir [0000-0002-3488-2078], Rubinsztein, David [0000-0001-5002-5263], Apollo - University of Cambridge Repository, Sarkar, Sovan, Korolchuk, Viktor I., Renna, Maurizio, Imarisio, Sara, Fleming, Angeleen, Mazza, WILLIAM ANDREA, Garcia-Arencibia, Moise, Rose, Claudia, Luo, Shouqing, Underwood, Benjamin R., Kroemer, Guido, O'Kane, Cahir J., Rubinsztein, David C.

المصدر: Molecular Cell

مصطلحات موضوعية: Autophagosome, mTORC1, HeLa Cell, chemistry.chemical_compound, Mice, 0302 clinical medicine, HEK293 Cell, Enzyme Inhibitor, Protein Isoforms, Enzyme Inhibitors, Phosphorylation, Membrane Protein, Class III Phosphatidylinositol 3-Kinase, Nuclear Protein, 0303 health sciences, Huntingtin Protein, Apoptosis Regulatory Protein, biology, TOR Serine-Threonine Kinase, TOR Serine-Threonine Kinases, Neurodegeneration, Nuclear Proteins, 3. Good health, Cell biology, I-kappa B Kinase, Nitric oxide synthase, Huntington Disease, NG-Nitroarginine Methyl Ester, Proto-Oncogene Proteins c-bcl-2, Beclin-1, Human, Nerve Tissue Proteins, Mechanistic Target of Rapamycin Complex 1, Nitric Oxide, Article, Nitric oxide, Cell Line, 03 medical and health sciences, Tuberous Sclerosis Complex 2 Protein, medicine, Autophagy, Animals, Humans, Mitogen-Activated Protein Kinase 8, Molecular Biology, 030304 developmental biology, Tumor Suppressor Protein, Animal, Protein, Tumor Suppressor Proteins, AMPK, Protein Isoform, Membrane Proteins, Proteins, Cell Biology, medicine.disease, Class III Phosphatidylinositol 3-Kinases, Rats, HEK293 Cells, chemistry, Multiprotein Complexes, Nerve Tissue Protein, biology.protein, Multiprotein Complexe, Rat, Nitric Oxide Synthase, Apoptosis Regulatory Proteins, 030217 neurology & neurosurgery, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209d48dfccc0685060c450c44197eabbTest
http://europepmc.org/articles/PMC3149661Test

المؤلفون: Sovan Sarkar, Viktor I. Korolchuk, Brinda Ravikumar, Ashley R. Winslow, Janet E. Davies, Dunecan Massey, Shouqing Luo, Usha Narayanan, Zeyn W. Green-Thompson, Moisés García-Arencibia, Benjamin R. Underwood, Farah H. Siddiqi, Maike Lichtenberg, Maria Jimenez-Sanchez, Fiona M. Menzies, David C. Rubinsztein, Kevin Moreau, Maurizio Renna, Marie Futter

المساهمون: Ravikumar, Brinda, Sarkar, Sovan, Davies, Janet E., Futter, Marie, Garcia-Arencibia, Moise, Green-Thompson, Zeyn W., Jimenez-Sanchez, Maria, Korolchuk, Viktor I., Lichtenberg, Maike, Luo, Shouqing, Massey, Dunecan C. O., Menzies, Fiona M., Moreau, Kevin, Narayanan, Usha, Renna, Maurizio, Siddiqi, Farah H., Underwood, Benjamin R., Winslow And, Ashley R., Rubinsztein, David C.

المصدر: Physiological Reviews. 90:1383-1435

مصطلحات موضوعية: Physiology, Epiphenomenon, Eukaryotic Cell, Disease, Biology, Mammal, Downregulation and upregulation, Stress, Physiological, Phagosomes, Physiology (medical), Autophagy, medicine, Animals, Humans, Molecular Biology, Phagosome, Mammals, Animal, Autophagy database, Neurodegeneration, General Medicine, medicine.disease, Cell biology, Eukaryotic Cells, Cytoplasm, Signal transduction, Human, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316b80a8b46b28f6911271c0c17edd0cTest
https://doi.org/10.1152/physrev.00030.2009Test

المؤلفون: Michael P. Murphy, Charles Joseph O'Kane, Phoebe Heard, Angeleen Fleming, Claudia Rose, David C. Rubinsztein, Sovan Sarkar, Gauri Krishna, Marie Quick, Moisés García-Arencibia, Benjamin R. Underwood, Viktor I. Korolchuk, Maurizio Renna, Sara Imarisio

المساهمون: Underwood, Benjamin [0000-0003-3427-9487], Fleming, Angeleen [0000-0003-3721-7126], O'Kane, Cahir [0000-0002-3488-2078], Murphy, Mike [0000-0003-1115-9618], Rubinsztein, David [0000-0001-5002-5263], Apollo - University of Cambridge Repository, Underwood, Benjamin R., Imarisio, Sara, Fleming, Angeleen, Rose, Claudia, Krishna, Gauri, Heard, Phoebe, Quick, Marie, Korolchuk, Viktor I., Renna, Maurizio, Sarkar, Sovan, García-arencibia, Moisé, O'Kane, Cahir J., Murphy, Michael P., Rubinsztein, David C.

المصدر: Human Molecular Genetics

مصطلحات موضوعية: Antioxidant, medicine.medical_treatment, Cercopithecus aethiop, Disease, HeLa Cell, medicine.disease_cause, Antioxidants, Mice, 0302 clinical medicine, Chlorocebus aethiops, Zebrafish, Genetics (clinical), chemistry.chemical_classification, 0303 health sciences, Neurodegeneration, Neurodegenerative Diseases, Articles, General Medicine, 3. Good health, Cell biology, Biochemistry, Peptide, COS Cells, Toxicity, Drosophila, Reactive Oxygen Specie, Human, Biology, 03 medical and health sciences, Genetic, COS Cell, Autophagy, Genetics, medicine, Animals, Humans, Molecular Biology, 030304 developmental biology, Reactive oxygen species, Neurodegenerative Disease, Animal, Oxidative Stre, medicine.disease, biology.organism_classification, Mice, Inbred C57BL, Disease Models, Animal, Oxidative Stress, chemistry, Peptides, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0840f5420c83edef34f71184b374039Test
https://doi.org/10.1093/hmg/ddq253Test

المؤلفون: Gautam Goel, Szu Yu Kuo, Kara L. Conway, Kara G. Lassen, Dorothea Maetzel, Rudolf Jaenisch, Petric Kuballa, Sovan Sarkar, Alykhan F. Shamji, Leslie N. Aldrich, Vlado Dančík, Isabel J. Latorre, Paul A. Clemons, Adam B. Castoreno, Ramnik J. Xavier, Stuart L. Schreiber

المصدر: Proceedings of the National Academy of Sciences. 112

مصطلحات موضوعية: Genetics, Medical, Green Fluorescent Proteins, Induced Pluripotent Stem Cells, Interleukin-1beta, Cellular homeostasis, Context (language use), Biology, Models, Biological, Small Molecule Libraries, Niemann-Pick C1 Protein, Autophagy, medicine, Humans, Enhancer, Cell Aggregation, Neurons, Membrane Glycoproteins, Multidisciplinary, Bacteria, Neurodegeneration, Intracellular Signaling Peptides and Proteins, Niemann-Pick Disease, Type C, medicine.disease, Phenotype, Human genetics, Cell aggregation, High-Throughput Screening Assays, Cell biology, PNAS Plus, Carrier Proteins, Peptides, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a055d21881399a769ee1e590baf6c3Test
https://doi.org/10.1073/pnas.1512289112Test

المؤلفون: Carmen Aguado, Olga Criado-García, Santiago Vernia, David C. Rubinsztein, Pascual Sanz, Viktor I. Korolchuk, Santiago Rodríguez de Córdoba, Sovan Sarkar, Erwin Knecht, Patricia Boya

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Proteasome Endopeptidase Complex, Ubiquitin-Protein Ligases, Protein tyrosine phosphatase, Biology, glycogen metabolism, Lafora disease, Inclusion bodies, malin, Mice, neurogeneration, medicine, Autophagy, Animals, Humans, Molecular Biology, Neurodegeneration, Cell Biology, medicine.disease, Spinal cord, Protein Tyrosine Phosphatases, Non-Receptor, Autophagic Punctum, medicine.anatomical_structure, Biochemistry, Cancer research, laforin, Carrier Proteins, Laforin, Intracellular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c60e8b4481d2d2537a0c77cac4a4505Test
http://hdl.handle.net/10261/53039Test