نتائج البحث - "Jack van Horssen"

1

Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders

المؤلفون: Pablo R. Moya, Niels Hellings, Tim Vanmierlo, Assia Tiane, Lieve van Veggel, Jack van Horssen, David M. Wilson, Melissa Schepers, Bert O. Eijnde, Elisabeth Piccart, Wim Derave, Jan H. Spaas, Rudy Schreiber

المصدر: Cellular and Molecular Life Sciences
Spaas, J, van Veggel, L, Schepers, M, Tiane, A, van Horssen, J, Wilson, D M, Moya, P R, Piccart, E, Hellings, N, Eijnde, B O, Derave, W, Schreiber, R & Vanmierlo, T 2021, ' Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders ', Cellular and Molecular Life Sciences, vol. 78, no. 10, pp. 4615-4637 . https://doi.org/10.1007/s00018-021-03802-0Test
CELLULAR AND MOLECULAR LIFE SCIENCES

مصطلحات موضوعية: 0301 basic medicine, Cell type, Central nervous system, Oxidative phosphorylation, Review, Biology, medicine.disease_cause, 03 medical and health sciences, Cellular and Molecular Neuroscience, Myelination, 0302 clinical medicine, Oligodendrocyte precursor cell, medicine, Medicine and Health Sciences, Animals, Humans, Remyelination, Neurodegeneration, Molecular Biology, Pharmacology, Oligodendrocyte Precursor Cells, Multiple sclerosis, Carbonyl stress, Biology and Life Sciences, Cell Differentiation, Cell Biology, medicine.disease, Oligodendrocyte, Cell biology, Oxidative Stress, stomatognathic diseases, 030104 developmental biology, medicine.anatomical_structure, nervous system, Oxidative stress, Molecular Medicine, Nervous System Diseases, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9b1af3fb7aed57f30ae9595bd0749eTest
http://www.scopus.com/inward/record.url?scp=85102348725&partnerID=8YFLogxKTest

2

Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

المؤلفون: Sina C. Rosenkranz, Simone Bauer, Charlotte Schubert, Jan Broder Engler, Simone Träger, Celina Schwencke-Westphal, Nanne Paauw, Artem A Shaposhnykov, Marc Freichel, Benjamin Schattling, Vanessa Roth, Jack van Horssen, Manuel A. Friese, Vanessa Vieira, Lukas Can Bal, Ole Pless, Maarten E. Witte

المساهمون: Molecular cell biology and Immunology, AII - Inflammatory diseases, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation, Publica

المصدر: eLife
eLife, 10:e61798, 1-60. eLife Sciences Publications Limited
eLife, Vol 10 (2021)
Rosenkranz, S C, Shaposhnykov, A A, Traeger, S, Engler, J B, Witte, M E, Roth, V, Vieira, V, Paauw, N, Bauer, S, Schwencke-Westphal, C, Schubert, C, Bal, L C, Schattling, B, Pless, O, van Horssen, J, Freichel, M & Friese, M A 2021, ' Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis ', eLife, vol. 10, e61798, pp. 1-60 . https://doi.org/10.7554/eLife.61798Test, https://doi.org/10.7554/eLife.61798Test

مصطلحات موضوعية: 0301 basic medicine, Male, Mitochondrial DNA, Multiple Sclerosis, Ppargc1a, Mouse, QH301-705.5, Science, Calcium buffering, oxidative phosphorylation, Inflammation, Biology, Mitochondrion, Neuroprotection, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Immunology and Inflammation, medicine, Animals, Biology (General), Neurons, General Immunology and Microbiology, EAE, General Neuroscience, Experimental autoimmune encephalomyelitis, Neurodegeneration, General Medicine, medicine.disease, Cell biology, Mitochondria, Disease Models, Animal, 030104 developmental biology, Medicine, neuroprotection, Female, PPARGC1A, medicine.symptom, 030217 neurology & neurosurgery, Research Article, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8d3e60a01db468e5ad64f4d602f157Test
https://doi.org/10.7554/elife.61798Test

3

Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

المؤلفون: Lydian Knoop, Alwin Kamermans, Susanne M. A. van der Pol, Svenja Kiljan, Marc Franssen, Geert J. Schenk, Carmen Picón, Jack van Horssen, Evelien Drost, Nicholas D. Mazarakis, Sandra Amor, Lynn van Olst, Richard Reynolds, Helga E. de Vries, Rachel E. James, Maarten E. Witte, Iliana Michailidou, Jeroen J. G. Geurts, Carla Rodriguez-Mogeda

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Anatomy and neurosciences, Amsterdam Neuroscience - Neurodegeneration, Pathology, AII - Inflammatory diseases, ACS - Microcirculation, Amsterdam Neuroscience - Neurovascular Disorders

المصدر: Acta Neuropathologica, 141(6), 881-899. Springer Verlag
van Olst, L, Rodriguez Mogeda, C, Picon, C, Kiljan, S, James, R E, Kamermans, A, van der Pol, S M A, Knoop, L, Michailidou, I, Drost, E, Franssen, M, Schenk, G J, Geurts, J J G, Amor, S, Mazarakis, N D, van Horssen, J, de Vries, H E, Reynolds, R & Witte, M E 2021, ' Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration ', Acta Neuropathologica, vol. 141, no. 6, pp. 881-899 . https://doi.org/10.1007/s00401-021-02293-4Test
Acta Neuropathologica

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0957b67feeac3b0e4dfd13e8b3902887Test
https://research.vumc.nl/en/publications/1f92b2d0-c8fa-4105-bbe6-f8f866702a82Test

4

Author response: Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

المؤلفون: Artem A Shaposhnykov, Marc Freichel, Celina Schwencke-Westphal, Maarten E. Witte, Nanne Paauw, Ole Pless, Jan Broder Engler, Sina C. Rosenkranz, Vanessa Vieira, Jack van Horssen, Lukas Can Bal, Benjamin Schattling, Simone Bauer, Charlotte Schubert, Vanessa Roth, Simone Träger, Manuel A. Friese

مصطلحات موضوعية: business.industry, Multiple sclerosis, Neurodegeneration, medicine, medicine.disease, business, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b6fb0804a7295cadd08a4e5eb4b484c1Test
https://doi.org/10.7554/elife.61798.sa2Test

5

Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter

المؤلفون: Rachel James, Richard Reynolds, Anusha Jayaraman, Carmen Picón, Patricia Gallego, Jack van Horssen, Catriona Beck, Maarten E. Witte, Nicholas D. Mazarakis

المساهمون: Molecular cell biology and Immunology, AII - Inflammatory diseases, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation, Multiple Sclerosis Society, National Multiple Sclerosis Society, Medical Research Council (MRC)

المصدر: Acta Neuropathologica
Acta Neuropathologica, 141(4), 585-604. Springer Verlag
Picon, C, Jayaraman, A, James, R, Beck, C, Gallego, P, Witte, M E, van Horssen, J, Mazarakis, N D & Reynolds, R 2021, ' Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter ', Acta Neuropathologica, vol. 141, no. 4, pp. 585-604 . https://doi.org/10.1007/s00401-021-02274-7Test, https://doi.org/10.1007/s00401-021-02274-7Test

مصطلحات موضوعية: Adult, Male, Necroptosis, Clinical Neurology, Apoptosis, Grey matter, Receptors, Tumor Necrosis Factor, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, RIPK1, Meninges, Pathology, medicine, Animals, Humans, FADD, Gray Matter, Neurodegeneration, Aged, Cerebral Cortex, Neurons, Original Paper, Science & Technology, Neurology & Neurosurgery, biology, Tumor Necrosis Factor-alpha, Neurosciences, 1103 Clinical Sciences, Middle Aged, Multiple Sclerosis, Chronic Progressive, medicine.disease, Cell biology, Rats, medicine.anatomical_structure, biology.protein, Cytokines, Tumor necrosis factor alpha, Female, Neurosciences & Neurology, Neurology (clinical), Neuron, Signal transduction, 1109 Neurosciences, Life Sciences & Biomedicine, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a1efddbfaa635db122af5a7ce2e3f5Test
https://pubmed.ncbi.nlm.nih.gov/33569629Test

6

Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

المؤلفون: Lynn van Olst, Carla Rodriguez-Mogeda, Carmen Picon-Munoz, Svenja Kiljan, Rachel E. James, Alwin Kamermans, Susanne M.A. van der Pol, Lydian Knoop, Evelien Drost, Marc Franssen, Geert Schenk, Jeroen J.G. Geurts, Sandra Amor, Nicholas D. Mazarakis, Jack van Horssen, Helga E. de Vries, Richard Reynolds, Maarten E. Witte

مصطلحات موضوعية: Microglia, Multiple sclerosis, Phagocytosis, Neurodegeneration, Meninges, Inflammation, Biology, medicine.disease, Phenotype, medicine.anatomical_structure, Cortex (anatomy), medicine, medicine.symptom, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7cadc3543b3664ab6af55209a5faad29Test
https://doi.org/10.1101/2020.09.03.281543Test

7

Enhancing mitochondrial activity in neurons protects against neurodegeneration in CNS inflammation

المؤلفون: Maarten E. Witte, Simone Bauer, Marc Freichel, Vanessa Vieira, Celina Schwencke-Westphal, Jan Broder Engler, Nanne Paauw, Ole Pless, Lukas Can Bal, Sina C. Rosenkranz, Jack van Horssen, Artem A Shaposhnykov, Simone Träger, Vanessa Roth, Manuel A. Friese, Benjamin Schattling

مصطلحات موضوعية: Mitochondrial DNA, Neurodegeneration, Calcium buffering, Central nervous system, Experimental autoimmune encephalomyelitis, Inflammation, Mitochondrion, Biology, medicine.disease, Neuroprotection, Cell biology, medicine.anatomical_structure, medicine, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::58416ed2b8ca880bcbb32df5c4637996Test
https://doi.org/10.1101/2020.06.19.161091Test

8

Setmelanotide, a Novel, Selective Melanocortin Receptor-4 Agonist Exerts Anti-inflammatory Actions in Astrocytes and Promotes an Anti-inflammatory Macrophage Phenotype

المؤلفون: Maarten E. Witte, Tom Verhoeven, Jasper J. Koning, Jack van Horssen, Bert van het Hof, Lauri Borghuis, Merel Rijnsburger, Alwin Kamermans, Helga E. de Vries

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, ACS - Microcirculation

المصدر: Kamermans, A, Verhoeven, T, van het Hof, B, Koning, J J, Borghuis, L, Witte, M, van Horssen, J, de Vries, H E & Rijnsburger, M 2019, ' Setmelanotide, a Novel, Selective Melanocortin Receptor-4 Agonist Exerts Anti-inflammatory Actions in Astrocytes and Promotes an Anti-inflammatory Macrophage Phenotype ', Frontiers in Immunology, vol. 10, 2312 . https://doi.org/10.3389/fimmu.2019.02312Test
Frontiers in Immunology, 10:2312
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Agonist, lcsh:Immunologic diseases. Allergy, medicine.drug_class, Immunology, Anti-Inflammatory Agents, macrophage, multiple sclerosis, Neuroprotection, 03 medical and health sciences, 0302 clinical medicine, astrocyte, Melanocortin receptor, medicine, Humans, Immunology and Allergy, melanocortin, Phosphorylation, Cyclic AMP Response Element-Binding Protein, Cells, Cultured, Original Research, Aged, melanocortin receptor-4, Interleukin-6, Chemistry, Macrophages, Neurodegeneration, Interleukin, Middle Aged, Interleukin-11, medicine.disease, Melanocortin 4 receptor, Phenotype, 030104 developmental biology, medicine.anatomical_structure, alpha-MSH, inflammation, Astrocytes, Cancer research, Receptor, Melanocortin, Type 4, Female, Melanocortin, lcsh:RC581-607, 030215 immunology, Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b17f5ae96d8db4852179819d9bb35Test
https://research.vumc.nl/en/publications/ca4f60ca-aecc-435f-9bd3-00a1d1002c6aTest

9

Inflammation and mitochondrial dysfunction

المؤلفون: Maarten E. Witte, Jack van Horssen, Pauline van Schaik

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Neuroscience Letters, 710:132931. Elsevier Ireland Ltd
van Horssen, J, van Schaik, P & Witte, M 2019, ' Inflammation and mitochondrial dysfunction : A vicious circle in neurodegenerative disorders? ', Neuroscience Letters, vol. 710, 132931 . https://doi.org/10.1016/j.neulet.2017.06.050Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dc4baab575355a8ae54ba627d82a95Test
https://doi.org/10.1016/j.neulet.2017.06.050Test

10

Experimental models of cortical multiple sclerosis pathology

المؤلفون: Jack van Horssen, Maarten E. Witte

المصدر: Witte, M E & van Horssen, J 2017, ' Experimental models of cortical multiple sclerosis pathology ', Drug Discovery Today: Disease Models, vol. 25-26, pp. 69-74 . https://doi.org/10.1016/j.ddmod.2018.09.002Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f291adfccfe899f7599407de472097f2Test
https://doi.org/10.1016/j.ddmod.2018.09.002Test

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