المؤلفون: Yap, TA, Krebs, MG, Postel-Vinay, S, El-Khouiery, A, Soria, J-C, Lopez, J, Berges, A, Cheung, SYA, Irurzun-Arana, I, Goldwin, A, Felicetti, B, Jones, GN, Lau, A, Frewer, P, Pierce, AJ, Clack, G, Stephens, C, Smith, SA, Dean, E, Hollingsworth, SJ

المساهمون: Lopez, Juanita

مصطلحات موضوعية: Antineoplastic Combined Chemotherapy Protocols, Ataxia Telangiectasia Mutated Proteins, Carboplatin, Humans, Indoles, Maximum Tolerated Dose, Morpholines, Neoplasms, Neutropenia, Nuclear Proteins, Protein Kinase Inhibitors, Pyrimidines, Sulfonamides, Sulfoxides, Thrombocytopenia

جغرافية الموضوع: United States

وصف الملف: Print; 5224; application/pdf

العلاقة: 1078-0432.CCR-21-1032; Clinical Cancer Research, 2021, 27 (19), pp. 5213 - 5224; https://repository.icr.ac.uk/handle/internal/5802Test

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-21-1032Test
https://repository.icr.ac.uk/handle/internal/5802Test

المؤلفون: Campbell, J, Ryan, CJ, Brough, R, Bajrami, I, Pemberton, HN, Chong, IY, Costa-Cabral, S, Frankum, J, Gulati, A, Holme, H, Miller, R, Postel-Vinay, S, Rafiq, R, Wei, W, Williamson, CT, Quigley, DA, Tym, J, Al-Lazikani, B, Fenton, T, Natrajan, R, Strauss, SJ, Ashworth, A, Lord, CJ

المساهمون: Campbell, James, Chong, Yu-Shing, Al-Lazikani, Bissan, Natrajan, Rachael, Lord, Christopher

مصطلحات موضوعية: Cell Line, Tumor, Humans, Neoplasms, Protein Kinases, Receptor, erbB-2, RNA, Small Interfering, Gene Expression Profiling, RNA Interference, Mutation, Fibroblast Growth Factor, Type 1, Smad4 Protein

وصف الملف: Print-Electronic; 2501; application/pdf

العلاقة: Cell reports, 2016, 14 (10), pp. 2490 - 2501; https://repository.icr.ac.uk/handle/internal/109Test

الإتاحة: https://doi.org/10.1016/j.celrep.2016.02.023Test
https://repository.icr.ac.uk/handle/internal/109Test

المؤلفون: Touat, M, Sourisseau, T, Dorvault, N, Chabanon, RM, Garrido, M, Morel, D, Krastev, DB, Bigot, L, Adam, J, Frankum, JR, Durand, S, Pontoizeau, C, Souquère, S, Kuo, M-S, Sauvaigo, S, Mardakheh, F, Sarasin, A, Olaussen, KA, Friboulet, L, Bouillaud, F, Pierron, G, Ashworth, A, Lombès, A, Lord, CJ, Soria, J-C, Postel-Vinay, S

المساهمون: Krastev, Dragomir, Lord, Christopher

مصطلحات موضوعية: Animals, Humans, Mice, Nude, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms, Experimental, NAD, Endonucleases, DNA-Binding Proteins, Neoplasm Proteins, Cytokines, DNA Repair, Nicotinamide Phosphoribosyltransferase, A549 Cells

وصف الملف: Print-Electronic; 1687; application/pdf

العلاقة: The Journal of clinical investigation, 2018, 128 (4), pp. 1671 - 1687; https://repository.icr.ac.uk/handle/internal/2869Test

الإتاحة: https://doi.org/10.1172/jci90277Test
https://repository.icr.ac.uk/handle/internal/2869Test

المؤلفون: Carden, CP, Sarker, D, Postel-Vinay, S, Yap, TA, Attard, G, Banerji, U, Garrett, MD, Thomas, GV, Workman, P, Kaye, SB, de Bono, JS

المساهمون: Garrett, Michelle Dawn, De Bono, Johann, Banerji, Udai, Workman, Paul, Kaye, Stanley Bernard, Attard, Gerhardt, Yap, Timothy, Turner, Lydia

مصطلحات موضوعية: Humans, Neoplasms, Antineoplastic Agents, Drug Approval, Pharmacogenetics, Models, Biological, Patient Selection, Clinical Trials, Phase I as Topic, Biomarkers, Pharmacological, Drug Discovery

وصف الملف: Print-Electronic; 97

العلاقة: Drug discovery today, 2010, 15 (3-4), pp. 88 - 97; https://repository.icr.ac.uk/handle/internal/1964Test

الإتاحة: https://doi.org/10.1016/j.drudis.2009.11.006Test
https://repository.icr.ac.uk/handle/internal/1964Test

المؤلفون: Illouz, Frédéric, Wang, Daniel Y, Ye, Fei, Zhao, Shilin, Johnson, Douglas B, Gupta, A., De Felice, K. M., Loftus, E. V., Khanna, S., Beck, Kimberly E., Blansfield, Joseph A., Tran, Khoi Q., Feldman, Andrew L., Hughes, Marybeth S., Royal, Richard E., Kammula, Udai S., Topalian, Suzanne L., Sherry, Richard M., Kleiner, David, Quezado, Martha, Lowy, Israel, Yellin, Michael, Rosenberg, Steven A., Yang, James C., Michot, J. M., Bigenwald, C., Champiat, S., Collins, M., Carbonnel, Franck, Postel-Vinay, S., Berdelou, A., Varga, A., Bahleda, R., Hollebecque, A., Massard, C., Fuerea, A., Ribrag, V., Gazzah, A., Armand, J. P., Amellal, N., Angevin, E., Noel, N., Boutros, C., Mateus, C., Robert, C., Soria, J. C., Marabelle, A., Lambotte, O., Gonzalez, Raul S., Salaria, Safia N., Bohannon, Caitlin D., Huber, Aaron R., Feely, Michael M., Shi, Chanjuan, Marthey, L., Mussini, C., Nachury, M., Nancey, S., Grange, F., Zallot, C., Peyrin-Biroulet, L., Rahier, J. F., de Beauregard, M. Bourdier, Mortier, L., Coutzac, C., Soularue, E., Lanoy, E., Kapel, N., Planchard, D., Chaput, N., Benson, Al B., Ajani, Jaffer A., Catalano, Robert B., Engelking, Constance, Kornblau, Steven M., Martenson, James A., McCallum, Richard, Mitchell, Edith P., O'Dorisio, Thomas M., Vokes, Everett E., Wadler, Scott, Haanen, J B A G, Kerr, K M, Peters, S, Larkin, J, Jordan, K, Bergqvist, Viktoria, Hertervig, Erik, Gedeon, Peter, Kopljar, Marija, Griph, Håkan, Kinhult, Sara, Carneiro, Ana, Marsal, Jan, Hsieh, Amy Hsin Chieh, Ferman, Mutaz, Brown, Michael P., Andrews, Jane M., Trainer, Harris, Hulse, Paul, Higham, Claire E, Trainer, Peter, Lorigan, Paul, Hughes, Jing, Vudattu, Nalini, Sznol, Mario, Gettinger, Scott, Kluger, Harriet, Lupsa, Beatrice, Herold, Kevan C

المصدر: Illouz, F, Wang, D Y, Ye, F, Zhao, S, Johnson, D B, Gupta, A, De Felice, K M, Loftus, E V, Khanna, S, Beck, K E, Blansfield, J A, Tran, K Q, Feldman, A L, Hughes, M S, Royal, R E, Kammula, U S, Topalian, S L, Sherry, R M, Kleiner, D, Quezado, M, Lowy, I, Yellin, M, Rosenberg, S A, Yang, J C, Michot, J M, Bigenwald, C, Champiat, S, Collins, M, Carbonnel, F, Postel-Vinay, S, Berdelou, A, Varga, A, Bahleda, R, Hollebecque, A, Massard, C, Fuerea, A, Ribrag, V, Gazzah, A, Armand, J P, Amellal, N, Angevin, E, Noel, N, Boutros, C, Mateus, C, Robert, C, Soria, J C, Marabelle, A, Lambotte, O, Gonzalez, R S, Salaria, S N, Bohannon, C D, Huber, A R, Feely, M M, Shi, C, Marthey, L, Mateus, C, Mussini, C, Nachury, M, Nancey, S, Grange, F, Zallot, C, Peyrin-Biroulet, L, Rahier, J F, de Beauregard, M B, Mortier, L, Coutzac, C, Soularue, E, Lanoy, E, Kapel, N, Planchard, D, Chaput, N, Robert, C, Carbonnel, F, Benson, A B, Ajani, J A, Catalano, R B, Engelking, C, Kornblau, S M, Martenson, J A, McCallum, R, Mitchell, E P, O'Dorisio, T M, Vokes, E E, Wadler, S, Haanen, J B A G, Carbonnel, F, Robert, C, Kerr, K M, Peters, S, Larkin, J, Jordan, K, Bergqvist, V, Hertervig, E, Gedeon, P, Kopljar, M, Griph, H, Kinhult, S, Carneiro, A, Marsal, J, Hsieh, A H C, Ferman, M, Brown, M P, Andrews, J M, Trainer, H, Hulse, P, Higham, C E, Trainer, P, Lorigan, P, Hughes, J, Vudattu, N, Sznol, M, Gettinger, S, Kluger, H, Lupsa, B & Herold, K C 2006, ' Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4 ', Journal of Clinical Oncology, pp. 2283-2289 . https://doi.org/10.1200/JCO.2005.04.5716Test

مصطلحات موضوعية: Male, Skin Neoplasms, Cytotoxic, medicine.medical_treatment, Autoimmunity, Dermatitis, Lymphocyte Activation, Gastroenterology, Immune-related adverse events, T-Lymphocyte Subsets, Adrenal Cortex Hormones, 80 and over, Immune-checkpoint inhibitor induced enterocolitis, Neoplasm Metastasis, Melanoma, Enterocolitis, Membrane Glycoproteins, Subcutaneous, Vaccination, Antibodies, Monoclonal, programmed cell death protein 1, Kidney Neoplasms, Neoplasm Proteins, Oncology, Disease Progression, chemically induced, Lung cancer, Nivolumab, gastroenteritis, Type 1, medicine.medical_specialty, Antineoplastic Agents, chemistry, Antigen, Antigens, CD, HLA-A2 Antigen, Diabetes Mellitus, Humans, Tumour neoantigen, Aged, ResearchInstitutes_Networks_Beacons/mcrc, Immunotherapy, medicine.disease, Peptide Fragments, Immunology, adverse effects, gastrointestinal tract, Peptides, Immune checkpoint blockade, Autoimmune, Cancer Research, colitis, T-Lymphocytes, Programmed Cell Death 1 Receptor, administration & dosage, Anti-CTLA-4, Hepatitis, immunology, Neoplasms, Monoclonal, CTLA-4 Antigen, Manchester Cancer Research Centre, Anti-PD-1 antibody, Cytotoxic T-lymphocyte-associated antigen 4, Middle Aged, CD, Differentiation, Female, immunotherapy, medicine.symptom, Intravenous, gp100 Melanoma Antigen, medicine.drug, Adult, etiology, Vitiligo, chemical and pharmacologic phenomena, Ipilimumab, Cancer Vaccines, Antibodies, Autoimmune Diseases, Injections, Gastrointestinal Agents, blood, Internal medicine, Immune Tolerance, medicine, Antigens, Vedolizumab treatment against irAEs, Carcinoma, Renal Cell, Salvage Therapy, therapy, business.industry, Cancer, Antigens, Differentiation, Infliximab, therapeutic use, physiology, Neoplasm, pathology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f963594b903746c33682947dc0a8bfTest
https://doi.org/10.1200/jco.2005.04.5716Test

المؤلفون: Johann S. de Bono, Petri Bono, John Aspegren, Sophie Postel-Vinay, Amir Snapir, Malaka Ameratunga, Irene Brana, Ruth Plummer, Timo Korjamo

المساهمون: HUS Comprehensive Cancer Center, Heikki Joensuu / Principal Investigator, Department of Oncology, Institut Català de la Salut, [Ameratunga M] The Institute of Cancer Research and Royal Marsden, London, UK. Monash University, Melbourne, Australia. [Braña I] Vall d’Hebron Institut of Oncology (VHIO), Barcelona, Spain. [Bono P] Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland. University of Helsinki, Helsinki, Finland. Terveystalo Finland and University of Helsinki, Helsinki, Finland. [Postel-Vinay S] Drug Development Department, DITEP, Gustave Roussy, Villejuif, France. [Plummer R] Translational and Clinical Research Institute, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. [Aspegren J] Orion Corporation Orion Pharma, Espoo, Finland, Vall d'Hebron Barcelona Hospital Campus

المصدر: British Journal of Cancer
Scientia

مصطلحات موضوعية: Male, Cancer Research, Lung Neoplasms, Pyridines, Administration, Oral, Càncer - Quimioteràpia, Other subheadings::Other subheadings::/drug therapy [Other subheadings], Gastroenterology, RECOMMENDATIONS, Medicaments antineoplàstics, 0302 clinical medicine, Breast cancer, Carcinoma, Non-Small-Cell Lung, Neoplasms, LYMPHOMA, Medicine, Melanoma, Oxazoles, Fatigue, Ovarian Neoplasms, 0303 health sciences, Prostate cancer, Pharmaceutics, Lymphoma, Non-Hodgkin, Sarcoma, Middle Aged, CANCER, 3. Good health, Prostatic Neoplasms, Castration-Resistant, Editorial, Oncology, 030220 oncology & carcinogenesis, Toxicity, Vomiting, Quinolines, Female, Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents [CHEMICALS AND DRUGS], medicine.symptom, Adult, Blood Platelets, medicine.medical_specialty, Adolescent, Maximum Tolerated Dose, Nausea, 3122 Cancers, Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores], Biological Availability, Antineoplastic Agents, Breast Neoplasms, Drug development, Anorexia, Article, Drug Administration Schedule, neoplasias [ENFERMEDADES], BET inhibitor, 03 medical and health sciences, Young Adult, Pharmacokinetics, Protein Domains, Internal medicine, DOSE-ESCALATION, Humans, 030304 developmental biology, Aged, business.industry, acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antineoplásicos [COMPUESTOS QUÍMICOS Y DROGAS], Proteins, Small Cell Lung Carcinoma, P-TEFB, Discontinuation, Neoplasms [DISEASES], Clinical trial, business, BROMODOMAIN INHIBITION

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2306c38aafebd4ec618c7b751cd3d071Test
https://pubmed.ncbi.nlm.nih.gov/32989227Test