التفاصيل البيبلوغرافية
| العنوان: |
Presymptomatic testing for BRCA1 and BRCA2: how distressing are the pre-test weeks? Rotterdam/Leiden Genetics Working Group |
| المؤلفون: |
Lodder, L. (Litanja), Devilee, P. (Peter), Niermeijer, M.F. (Martinus), Cornelisse, C.J. (Cees), Frets, P.G., Trijsburg, R.W. (Wim), Meijers-Heijboer, E.J. (Hanne), Klijn, J.G.M. (Jan), Duivenvoorden, H.J. (Hugo), Tibben, A. (Arend), Wagner, A. (Anja), Meer, C.A. van der |
| المصدر: |
Journal of Medical Genetics |
| سنة النشر: |
1999 |
| المجموعة: |
RePub - Publications from Erasmus University, Rotterdam |
| مصطلحات موضوعية: |
Adult, Aged, Anxiety/psychology, BRCA1 Protein/*genetics, BRCA2 Protein, Breast Neoplasms/genetics/*psychology, Female, Genetic Markers, Genetic Screening/*psychology, Humans, Middle aged, Neoplasm Proteins/*genetics, Research Support, Non-U.S. Gov't, Transcription Factors/*genetics |
| الوصف: |
Presymptomatic DNA testing for autosomal dominant hereditary breast/ovarian cancer (HBOC) became an option after the identification of the BRCA1 and BRCA2 genes in 1994-1995. Healthy female mutation carriers have a high lifetime risk for breast cancer (56-87%) or ovarian cancer (10-60%) and may opt for intensive breast and ovary surveillance or prophylactic surgery (mastectomy/oophorectomy).We studied general and cancer related distress in 85 healthy women with a 25% or 50% risk of being carrier of a BRCA1/BRCA2 gene mutation and 66 partners in the six to eight week |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://repub.eur.nl/pub/9211Test; urn:hdl:1765/9211 |
| الإتاحة: |
http://repub.eur.nl/pub/9211Test |
| حقوق: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.9C399E8B |
| قاعدة البيانات: |
BASE |
