دورية أكاديمية
The prevalence, serogroup distribution and risk factors of meningococcal carriage in adolescents and young adults in Turkey
| العنوان: | The prevalence, serogroup distribution and risk factors of meningococcal carriage in adolescents and young adults in Turkey |
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| المؤلفون: | Rahmi Tuna Tekin, Ener Cagri Dinleyici, Mehmet Ceyhan, Adem Karbuz, Nuran Salman, Murat Sutçu, Zafer Kurugol, Yasemin Balliel, Melda Celik, Mustafa Hacimustafaoglu, Necdet Kuyucu, Meda Kondolot, Gülnar Sensoy, Ozge Metin, Soner Sertan Kara, Meltem Dinleyici, Omer Kılıç, Cihangul Bayhan, Venhar Gurbuz, Emre Aycan, Aygun Memedova, Arzu Karli, Gulçin Bozlu, Solmaz Celebi |
| المصدر: | Human Vaccines & Immunotherapeutics, Vol 13, Iss 5, Pp 1182-1189 (2017) |
| بيانات النشر: | Taylor & Francis Group |
| سنة النشر: | 2017 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | adolescents, meningococci, meningococcal vaccines, nasopharyngeal colonization, neisseria meningitidis, turkey, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | The serogroup epidemiology of invasive meningococcal disease (IMD), which varies considerably by geographic region and immunization schedule, changes continuously. Meningococcal carriage data are crucial for assessing IMD epidemiology and designing f potential vaccination strategies. Meningococcal seroepidemiology in Turkey differs from that in other countries: serogroups W and B are the predominant strains for IMD during childhood, whereas no serogroup C cases were identified over the last 10 y and no adolescent peak for IMD was found. There is a lack of data on meningococcal carriage that represents the whole population. The aims of this multicenter study (12 cities in Turkey) were to evaluate the prevalence of Neisseria meningitidis carriage, the serogroup distribution and the related risk factors (educational status, living in a dormitory or student house, being a household contact with Hajj pilgrims, smoking, completion of military service, attending bars/clubs) in 1518 adolescents and young adults aged 10–24 y. The presence of N. meningitidis DNA was tested, and a serogroup analysis was performed using polymerase chain reaction. The overall meningococcal carriage rate was 6.3% (n = 96) in the study population. A serogroup distribution of the 96 N. meningitidis strains isolated from the nasopharyngeal specimens revealed serogroup A in 5 specimens (5.2%), serogroup B in 9 specimens (9.4%), serogroup W in 64 specimens (66.6%), and serogroup Y in 4 specimens (4.2%); 14 were classified as non-grouped (14.4%). No serogroup C cases were detected. The nasopharyngeal meningococcal carriage rate was 5% in the 10–14 age group, 6.4% in the 15–17 age-group, and 4.7% in the 18–20 age group; the highest carriage rate was found in the 21–24 age group (9.1%), which was significantly higher than those of the other age groups (p < 0.05). The highest carriage rate was found in 17-year-old adolescents (11%). The carriage rate was higher among the participants who had had close contact with Hajj/Umrah pilgrims (p < 0.01) ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2164-5515 2164-554X |
| العلاقة: | http://dx.doi.org/10.1080/21645515.2016.1268304Test; https://doaj.org/toc/2164-5515Test; https://doaj.org/toc/2164-554XTest; https://doaj.org/article/391ff9044ce64771b25452c5eac65577Test |
| DOI: | 10.1080/21645515.2016.1268304 |
| الإتاحة: | https://doi.org/10.1080/21645515.2016.1268304Test https://doaj.org/article/391ff9044ce64771b25452c5eac65577Test |
| رقم الانضمام: | edsbas.4EBCC6C3 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 21645515 2164554X |
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| DOI: | 10.1080/21645515.2016.1268304 |