التفاصيل البيبلوغرافية
| العنوان: |
Validity, reliability, and sensitivity to change of the myasthenia gravis activities of daily living profile in a sample of Italian myasthenic patients. |
| المؤلفون: |
Raggi, Alberto1 alberto.raggi@istituto-besta.it, Antozzi, Carlo2, Baggi, Fulvio2, Leonardi, Matilde1, Maggi, Lorenzo2, Mantegazza, Renato2 |
| المصدر: |
Neurological Sciences. Nov2017, Vol. 38 Issue 11, p1927-1931. 5p. |
| مصطلحات موضوعية: |
*MYASTHENIA gravis, *KRUSKAL-Wallis Test, *RANK correlation (Statistics), *PATIENTS, *WILCOXON signed-rank test, *COMPARATIVE studies, *FUNCTIONAL assessment, *LONGITUDINAL method, *RESEARCH methodology, *MEDICAL cooperation, *RESEARCH, *SELF-evaluation, *ACTIVITIES of daily living, *EVALUATION research, *PSYCHOLOGY, *DIAGNOSIS, RESEARCH evaluation |
| مصطلحات جغرافية: |
ITALY |
| مستخلص: |
The purpose of this study is to report on the validity, reliability, and sensitivity of the myasthenia gravis activities of daily living profile (MG-ADL) in a sample of Italian patients. Patients with myasthenia gravis (MG) completed a protocol that included the MG-ADL, the WHO Disability Assessment Schedule (WHODAS 2.0), the Besta Neurological Institute rating scale for myasthenia gravis, and the MG-composite. Cronbach's alpha was used to test reliability, Spearman's correlation and intra-class correlation coefficient (ICC) to test short-term test-retest, Kruskal-Wallis test to assess differences in MG-ADL between patients with different disease severity, and Wilcoxon signed-rank test to assess sensitivity to change. In total, 58 patients were enrolled: 44 were females, mean MG duration 10.5 ± 10.4 years, mean MG-ADL 3.98 ± 3.07. The MG-ADL showed good internal consistency (alpha = .774), stability (test-retest correlation = .98, ICC = .97). It was superior to the WHODAS 2.0 in differentiating patients with different MG type and severity (P < .001), it showed higher sensitivity to change (P = .001 for improved and P = .007 for worsened patients) and higher correlation with the MG-composite (RHO = .625). Our analysis shows that the Italian version of the MG-ADL is valid, reliable, stable, and sensitive to change. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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