المؤلفون: Yasmin A. Kadry, Eric S. Witze, Jia-Ying Lee

المصدر: Open Biology, Vol 11, Iss 10 (2021)
Open Biology

مصطلحات موضوعية: Lung Neoplasms, QH301-705.5, Lipoylation, EGFR, Immunology, Adenocarcinoma of Lung, Review, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, lung, Proto-Oncogene Proteins p21(ras), Mice, Protein Domains, Palmitoylation, medicine, Animals, Humans, cancer, palmitoylation, Epidermal growth factor receptor, signalling, Biology (General), Review Articles, EGFR inhibitors, Egfr signalling, biology, General Neuroscience, Cancer, medicine.disease, ErbB Receptors, Gene Expression Regulation, Neoplastic, Signalling, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, Carcinogenesis, Acyltransferases, Signal Transduction, DHHC20

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a085d6bc23140dc47b5846ea0aa44fTest
https://royalsocietypublishing.org/doi/10.1098/rsob.210033Test

المؤلفون: A. Fernández Montes, E. Élez, A. Vivancos, N. Martínez, P. González, M. Covela, J. de la Cámara, A. Cousillas, J. C. Méndez, B. Graña, E. Aranda

المساهمون: Institut Català de la Salut, [Fernández Montes A] Medical Oncology Department, Complexo Hospitalario Universitario de Ourense, Ourense, Spain. [Élez E] Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Vivancos A] Cancer Genomics Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Martínez N] Medical Oncology Department, Hospital Universitario A Coruña, A Coruña, Spain. [González P] Medical Oncology Department, Hospital Universitario Álvaro Cunqueiro, Vigo, Spain. [Covela M] Medical Oncology Department, Hospital Universitario Lucus Augusti, Lugo, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia

مصطلحات موضوعية: Cancer Research, Circulating tumor DNA, EGFR inhibitors, Liquid biopsy, Metastatic colorectal cancer, Panitumumab, Cells::Cells, Cultured::Clone Cells [ANATOMY], Genetic Phenomena::Genetic Variation::Mutation [PHENOMENA AND PROCESSES], General Medicine, neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales [ENFERMEDADES], Clone Cells, Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [DISEASES], RAS mutant, Oncology, Còlon - Càncer, Antineoplastic Combined Chemotherapy Protocols, Colonic Neoplasms, Mutation, Recte - Càncer, Humans, células::células cultivadas::células clonales [ANATOMÍA], Fluorouracil, Clonatge molecular, Colorectal Neoplasms, fenómenos genéticos::variación genética::mutación [FENÓMENOS Y PROCESOS]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416be7a035a6458eb1b872ffd2b8f4dcTest
https://pubmed.ncbi.nlm.nih.gov/34997474Test

المؤلفون: Darren Cross, Matthew J. Martin, Carine M. Guérot, Nicolas Floc'h, Clare Gregson, Jonathan P. Orme, Michal Bista, Lin Xue, Xu Li, Amar Rahi, Xiliang Zhao, Richard A. Ward, L. Evans, Gail L. Wrigley, Arash Mosallanejad, Tieguang Yao, Claire McWhirter, David J. Hargreaves, Nicola Colclough, Sue Bickerton, Darren Mckerrecher, Peter Barton, Yang Ye, Yi Liu, Marta Wylot, M. Raymond V. Finlay, Xiaoming Kang, Eva M. Lenz, Daniel O'Neill, Verity Talbot, Olivier Lorthioir, Paul D. Smith

المصدر: Journal of medicinal chemistry. 64(18)

مصطلحات موضوعية: Mice, Nude, Antineoplastic Agents, Mice, SCID, medicine.disease_cause, T790M, Organophosphorus Compounds, In vivo, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Animals, Humans, Osimertinib, Epidermal growth factor receptor, Lung cancer, Cell potency, Protein Kinase Inhibitors, EGFR inhibitors, Mutation, biology, Chemistry, medicine.disease, Xenograft Model Antitumor Assays, Rats, ErbB Receptors, Pyrimidines, Drug Resistance, Neoplasm, Cancer research, biology.protein, Molecular Medicine, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58199c545ee296c2c44cec7db12bfba5Test
https://pubmed.ncbi.nlm.nih.gov/34491761Test

المؤلفون: John V. Heymach, Jacqulyne P. Robichaux, Xiuning Le, Monique B. Nilsson

المصدر: Cancer cell. 39(9)

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, Lung Neoplasms, Bevacizumab, VEGF receptors, Mutant, medicine.disease_cause, Egfr tki, Erlotinib Hydrochloride, Carcinoma, Non-Small-Cell Lung, medicine, Humans, Lung cancer, Protein Kinase Inhibitors, EGFR inhibitors, Mutation, biology, business.industry, medicine.disease, respiratory tract diseases, ErbB Receptors, Oncology, Cancer research, biology.protein, Erlotinib, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ed27d5c837b282f20bf90988adbce3Test
https://pubmed.ncbi.nlm.nih.gov/34388377Test

المؤلفون: Jiajia Gu, Suresh S. Ramalingam, Yong He, Qiming Wang, Lei Zhu, Guojing Zhang, Zhen Chen, Taofeek K. Owonikoko, Hongjing Zang, Shi-Yong Sun, Songqing Fan, Kevin D.-Y. Sun

المصدر: Cancer Res

مصطلحات موضوعية: Cancer Research, Proteasome Endopeptidase Complex, Mutant, Apoptosis, Protein degradation, medicine.disease_cause, Article, Proto-Oncogene Proteins c-myc, T790M, Cell Line, Tumor, Medicine, Animals, Humans, Osimertinib, Protein Kinase Inhibitors, EGFR inhibitors, Mutation, Gene knockdown, Acrylamides, Aniline Compounds, business.industry, Xenograft Model Antitumor Assays, respiratory tract diseases, ErbB Receptors, Disease Models, Animal, Oncology, Mechanism of action, Drug Resistance, Neoplasm, Cancer research, medicine.symptom, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eda8766e6b90596a52b1db1f3d1f4b5Test
https://europepmc.org/articles/PMC8448971Test/

المؤلفون: Shujing Shen, Ruipan Zheng, Peizhu Hu, Xingya Li, Ziheng Zhang, Yurong Wang

المصدر: BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cancer

مصطلحات موضوعية: Oncology, Male, Cancer Research, Lung Neoplasms, EGFR TKI, medicine.disease_cause, NSCLC, T790M, Exon, Resistance mechanism, Surgical oncology, Clinical outcomes, Carcinoma, Non-Small-Cell Lung, Epidermal growth factor receptor, RC254-282, EGFR inhibitors, education.field_of_study, Mutation, Aniline Compounds, biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Exons, Middle Aged, Progression-Free Survival, ErbB Receptors, Disease Progression, Female, Research Article, Adult, medicine.medical_specialty, Genotype, Population, Internal medicine, Genetics, medicine, Humans, education, Protein Kinase Inhibitors, Aged, Retrospective Studies, Acrylamides, business.industry, Retrospective cohort study, Genes, erbB-1, Mutagenesis, Insertional, EGFR exon 19 deletion-insertion, biology.protein, business, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afcb5b82c72a100d035448232dbecdcTest
https://pubmed.ncbi.nlm.nih.gov/34774017Test

المؤلفون: Kamrine E. Poels, Chelsi Napoli, Yosef Tobi, Helena A. Yu, Manli Shi, Weiwei Tan, Tom O. McDonald, Franziska Michor, Scott L. Weinrich, Shaon Chakrabarti, Yuli Wang, Aaron N. Hata, Adam J. Schoenfeld, Heidie Frisco-Cabanos, Alex Makhnin

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, Combination therapy, Cancer therapy, Cell Survival, Science, General Physics and Astronomy, Phases of clinical research, Antineoplastic Agents, General Biochemistry, Genetics and Molecular Biology, Article, Cohort Studies, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Humans, Medicine, Computer Simulation, Osimertinib, Dosing, Lung cancer, Quinazolinones, EGFR inhibitors, Acrylamides, Aniline Compounds, Models, Statistical, Multidisciplinary, business.industry, General Chemistry, Models, Theoretical, medicine.disease, Applied mathematics, Dacomitinib, ErbB Receptors, Clinical trial, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e0bdb52f3393033766da9119f216d6Test
http://europepmc.org/articles/PMC8211846Test

المؤلفون: Longke Ran, Jing Song, Fangzhou Song, Jiayi Lai, Shiqi Miao, Yongyao Tang, Chuang Ge, Weiqi Nian, Ruihan Luo, Xiao Xiao

المصدر: Briefings in Bioinformatics

مصطلحات موضوعية: Male, Lung Neoplasms, AcademicSubjects/SCI01060, DNA Copy Number Variations, Drug resistance, NSCLC, drug target, Epigenesis, Genetic, resistance, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Databases, Genetic, Biomarkers, Tumor, medicine, Humans, Lung cancer, genomic alteration, Molecular Biology, Gene, Aged, 030304 developmental biology, EGFR inhibitors, Genetic association, Aged, 80 and over, 0303 health sciences, Tumor microenvironment, business.industry, Computational Biology, Genetic Variation, FCGR3A, Molecular Sequence Annotation, systemic treatment, Genomics, DNA Methylation, Middle Aged, Prognosis, medicine.disease, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, DNA methylation, Cancer research, Problem Solving Protocol, Female, Transcriptome, business, Information Systems

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62737df9f8eb6b389b03b8ceacfd8658Test
https://doi.org/10.1093/bib/bbab187Test

المؤلفون: C. Hu, C.A. Leche, Kathryn M. Ferguson, Anatoly Kiyatkin, Mark A. Lemmon, S.E. Stayrook

مصطلحات موضوعية: Mutation, biology, Chemistry, Growth factor, medicine.medical_treatment, medicine.disease_cause, Epiregulin, medicine, Cancer research, biology.protein, Functional selectivity, Epidermal growth factor receptor, Receptor, Tyrosine kinase, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::12d18f098a15490623352d83fe407621Test
https://doi.org/10.1101/2021.05.04.442654Test

المؤلفون: Gege Gui, Charles G. Eberhart, Hongkai Ji, Weiqiang Zhou, Mingyao Ying, Shuli Xia, Bachuchu Lal, Yunqing Li, Yi Fu, Minling Gao, John Laterra

المصدر: Cancer Res

مصطلحات موضوعية: 0301 basic medicine, STAT3 Transcription Factor, Cancer Research, Cell, Antineoplastic Agents, Apoptosis, Mice, SCID, Biology, medicine.disease_cause, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Mice, Inbred NOD, Neurosphere, Radioresistance, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, Osimertinib, Transcription factor, EGFR inhibitors, Cell Proliferation, Mutation, Acrylamides, Aniline Compounds, Hyperactivation, Brain Neoplasms, Xenograft Model Antitumor Assays, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Cancer research, Female, Glioblastoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8713574eaa0f09e2168f87f01240957Test
https://europepmc.org/articles/PMC8277712Test/