المؤلفون: Alexander Jones, John Brognard, Yimin Yang, Gema Lordén, Alexandra C. Newton, Natalie L. Stephenson, Julia A. Callender

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 24

مصطلحات موضوعية: 0301 basic medicine, Aging, Neurodegenerative, Inbred C57BL, Alzheimer's Disease, Mice, 0302 clinical medicine, Catalytic Domain, Chlorocebus aethiops, enzyme mutation, 2.1 Biological and endogenous factors, Phosphorylation, PKC, Aetiology, Multidisciplinary, Chemistry, Brain, Cell biology, Protein destabilization, PNAS Plus, Gain of Function Mutation, Second messenger system, COS Cells, Signal transduction, Alzheimer’s disease, signal transduction, Signal Transduction, Protein Kinase C-alpha, Allosteric regulation, Down-Regulation, Catalysis, Cell Line, 03 medical and health sciences, Alzheimer Disease, Acquired Cognitive Impairment, Animals, Humans, Protein kinase A, Protein kinase C, Diacylglycerol kinase, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Mice, Inbred C57BL, Enzyme Activation, 030104 developmental biology, Protein kinase domain, Mutation, Calcium, Dementia, CRISPR-Cas Systems, 030217 neurology & neurosurgery, protein kinase C

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18276fc3e965284a0d17e12beae5ed5Test
https://escholarship.org/uc/item/3js1d9tnTest

المؤلفون: Julia A. Callender, Alexandra C. Newton

المصدر: Neuronal Signaling

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Biology, Molecular Bases of Health & Disease, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, medicine, Review Articles, Loss function, Protein kinase C, Diacylglycerol kinase, chemistry.chemical_classification, posttranslational modification, Post-Translational Modifications, Molecular Interactions, Neurodegeneration, neurodegeneration, Cancer, Alzheimer's disease, medicine.disease, Cell biology, 030104 developmental biology, Enzyme, chemistry, Mutation, 030217 neurology & neurosurgery, Neuroscience, protein kinase C

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1961077473400d72c05372787f79392eTest
https://doi.org/10.1042/ns20160005Test

المؤلفون: Elizabeth A. Roberts, Jessica E. Young, Mariah Dunlap, Lawrence S.B. Goldstein, Sol M. Reyna, Rik van der Kant, Grace Woodruff, Julia A. Callender

المصدر: Cell Reports, Vol 17, Iss 3, Pp 759-773 (2016)

مصطلحات موضوعية: 0301 basic medicine, PS1, Mutant, Endocytic cycle, Induced Pluripotent Stem Cells, Endocytic recycling, GTPase, Biology, Endocytosis, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Amyloid beta-Protein Precursor, Alzheimer Disease, medicine, Presenilin-1, endocytosis, Humans, RNA, Messenger, Axon, lcsh:QH301-705.5, Neurons, iPSC, FAD, Phenotype, Axons, Cell biology, Lipoproteins, LDL, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, Transcytosis, lcsh:Biology (General), nervous system, rab GTP-Binding Proteins, Mutation, lipids (amino acids, peptides, and proteins), Amyloid Precursor Protein Secretases, APP, Alzheimer’s disease, Low Density Lipoprotein Receptor-Related Protein-1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895ced638bc54630b5f43dd30c9d963dTest
https://europepmc.org/articles/PMC5796664Test/

المؤلفون: Basavaraj Hooli, Roberto Malinow, Michael Leitges, Kristina Mullin, Corina E. Antal, Alexandra C. Newton, Mathew A. Sherman, Julia A. Callender, Sylvain Lesné, Stephanie Alfonso, Rudolph E. Tanzi

المصدر: Science signaling, vol 9, iss 427

مصطلحات موضوعية: 0301 basic medicine, Aging, Hippocampus, Neurodegenerative, Alzheimer's Disease, medicine.disease_cause, Biochemistry, Synapse, Mice, Neoplasms, Chlorocebus aethiops, 2.1 Biological and endogenous factors, Aetiology, Mutation, Genome, COS cells, Neurodegenerative Diseases, Cell biology, Neurological, COS Cells, Alzheimer's disease, Human, Protein Kinase C-alpha, PDZ domain, Biology, Article, 03 medical and health sciences, Protein Domains, Alzheimer Disease, Acquired Cognitive Impairment, Genetics, medicine, Animals, Humans, Protein kinase A, Molecular Biology, Protein kinase C, Family Health, Genome, Human, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Cell Biology, medicine.disease, Brain Disorders, 030104 developmental biology, Synapses, Dementia, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12358b725c679c77ebbb2178a3b2af05Test
https://europepmc.org/articles/PMC5154619Test/