المؤلفون: David G. Schatz, Jean-Marie Buerstedde, Suhas S.P. Rao, Jukka Alinikula, Filip Šenigl, Yaakov Maman, Ravi K. Dinesh, Lubomira Pecnova, David Weisz, Jiri Hejnar, Rafael Casellas, Rashu B. Seth, Arina D. Omer, Erez Lieberman Aiden

المصدر: Cell reports
Cell Reports, Vol 29, Iss 12, Pp 3902-3915.e8 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Somatic hypermutation, RNA polymerase II, Computational biology, Genome, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Cell Line, Tumor, Cytidine Deaminase, Activation-induced (cytidine) deaminase, Humans, Enhancer, lcsh:QH301-705.5, Gene, Transcription factor, 030304 developmental biology, 0303 health sciences, biology, Lentivirus, Chromatin, 030104 developmental biology, Enhancer Elements, Genetic, HEK293 Cells, lcsh:Biology (General), Mutation, biology.protein, RNA Polymerase II, Somatic Hypermutation, Immunoglobulin, 030217 neurology & neurosurgery, Plasmids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a368ddd3906f056ea5c400d34747c64Test
https://doi.org/10.2139/ssrn.3383796Test

المؤلفون: J. Bachl, Jean-Marie Buerstedde, Randolph B. Caldwell

المصدر: Cytogenet. Genome Res. 117, 189-194 (2007)

مصطلحات موضوعية: B-Lymphocytes, Focus (computing), business.industry, Gene Expression, Biology, Cell Line, Protein evolution, Biotechnology, Green fluorescent protein, Directed enzyme evolution, In-vitro recombination, Somatic hypermutation, Gene conversion, Phage display, Region hypermutation, Antibody diversity, Escherichia-coli, Lympocyte line, B cell line, Genes, Reporter, Mutation, Genetics, Animals, Humans, business, Chickens, Molecular Biology, Genetics (clinical), Pharmaceutical industry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8c0db9cc2e133ab83b2b3ef573c606Test
https://doi.org/10.1159/000103179Test

المؤلفون: Jean-Marie Buerstedde, Joanna Wesoly, Roland Kanaar, Linda Bross, Heinz Jacobs

المساهمون: Molecular Genetics

المصدر: Eur. J. Immunol. 33, 352-357 (2003)
European Journal of Immunology, 33, 352-357. Wiley-VCH

مصطلحات موضوعية: Somatic cell, Immunology, Immunoglobulin Variable Region, RAD51, Somatic hypermutation, Biology, Immunoglobulin light chain, medicine.disease_cause, Polymerase Chain Reaction, Mice, Immunoglobulin lambda-Chains, medicine, Animals, Gene Rearrangement, B-Lymphocyte, Light Chain, Immunology and Allergy, Mutation frequency, Mice, Knockout, Recombination, Genetic, B-Lymphocytes, Mutation, Genes, Immunoglobulin, fungi, DNA Helicases, Nuclear Proteins, Germinal center, Germinal Center, Molecular biology, Homologous recombination, Rad54, Immunoglobulin lambda light chain, Immunization, Somatic Hypermutation, Immunoglobulin, Immunologic Memory

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526944d91715b75086345d5bb2515feTest
https://doi.org/10.1002/immu.200310009Test

المؤلفون: David G. Schatz, Jessica J. McDonald, Jean-Marie Buerstedde, Jukka Alinikula, Hiroshi Arakawa

المصدر: PLoS Biology
PLoS Biology, Vol 12, Iss 4, p e1001831 (2014)

مصطلحات موضوعية: B Cells, Transcription, Genetic, Lymphocyte Activation, Biochemistry, E-Box Elements, White Blood Cells, Gene Knockout Techniques, Mice, 0302 clinical medicine, Animal Cells, Nucleic Acids, Molecular Cell Biology, Biology (General), Immune Response, 0303 health sciences, B-Lymphocytes, Immune System Proteins, MEF2 Transcription Factors, General Neuroscience, NF-kappa B, Cytidine deaminase, 3. Good health, Enhancer Elements, Genetic, Cellular Types, General Agricultural and Biological Sciences, DNA modification, Research Article, QH301-705.5, Immune Cells, DNA transcription, Immunology, Green Fluorescent Proteins, Somatic hypermutation, Biology, General Biochemistry, Genetics and Molecular Biology, Antibodies, Cell Line, Affinity maturation, 03 medical and health sciences, Immunoglobulin kappa-Chains, Immunoglobulin lambda-Chains, Cytidine Deaminase, Genetics, Animals, Humans, Enhancer, Uracil-DNA Glycosidase, Gene, Transcription factor, 030304 developmental biology, Blood Cells, Binding Sites, General Immunology and Microbiology, Biology and life sciences, Point mutation, Proteins, DNA, Cell Biology, Molecular biology, Mutation, Gene expression, Somatic Hypermutation, Immunoglobulin, Chickens, Sequence Alignment, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2c7f03381e457777efb988037e9aaTest
http://europepmc.org/articles/PMC3972084Test

المؤلفون: Jean-Marie Buerstedde, Karl Heinimann, Hansjakob Müller, Karl Siebold, Rodney J. Scott, Walter Weber, Zuzana Dobbie, Michèle Attenhofer

المصدر: Cancer. 85:2512-2518

مصطلحات موضوعية: Genetics, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Amsterdam criteria, Mutation, business.industry, Colorectal cancer, nutritional and metabolic diseases, Cancer, Microsatellite instability, Gene mutation, medicine.disease, medicine.disease_cause, digestive system diseases, Germline mutation, Oncology, Medicine, DNA mismatch repair, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7000aa89726d22f353b59788b793bb52Test
https://doi.org/10.1002Test/(sici)1097-0142(19990615)85:12<2512::aid-cncr4>3.0.co;2-g

المؤلفون: Jean-Marie Buerstedde, Yuko Yamaguchi-Iwai, Arkadiy Silbergleit, Shunichi Takeda, Olga Bezzubova

المصدر: Cell. 89:185-193

مصطلحات موضوعية: Immunoglobulin gene, Alkylating Agents, DNA, Complementary, Saccharomyces cerevisiae Proteins, Mitotic crossover, DNA repair, Molecular Sequence Data, Mutant, DNA, Recombinant, Gene Conversion, Saccharomyces cerevisiae, Biology, Radiation Tolerance, General Biochemistry, Genetics and Molecular Biology, Cell Line, Fungal Proteins, Animals, Amino Acid Sequence, Gene conversion, Cloning, Molecular, Recombination, Genetic, B-Lymphocytes, Base Sequence, Genes, Immunoglobulin, Sequence Homology, Amino Acid, Biochemistry, Genetics and Molecular Biology(all), fungi, DNA Helicases, Gene targeting, Methyl Methanesulfonate, Molecular biology, Non-homologous end joining, DNA Repair Enzymes, Immunoglobulin M, Gamma Rays, Gene Targeting, Mutation, Immunoglobulin Light Chains, Homologous recombination, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0c3e6b8f33ddf483b1021a4a5b3787Test
https://doi.org/10.1016/s0092-8674Test(00)80198-1

المؤلفون: Jamie L. Duke, David G. Schatz, Steven H. Kleinstein, Sally Tan, Hiroshi Arakawa, Kristin M. Kohler, Jean-Marie Buerstedde, Jessica J. McDonald

المصدر: Journal of immunology (Baltimore, Md. : 1950). 189(11)

مصطلحات موضوعية: Chromatin Immunoprecipitation, Transcription, Genetic, DNA damage, Immunology, Immunoglobulin Variable Region, Somatic hypermutation, RNA polymerase II, Biology, Article, Affinity maturation, Cytidine Deaminase, Serine, Immunology and Allergy, Animals, 3' Flanking Region, Phosphorylation, Enhancer, Gene, Cells, Cultured, Genetics, Immunoassay, B-Lymphocytes, Genes, Immunoglobulin, Cytidine deaminase, DNA, Enhancer Elements, Genetic, Genetic Loci, Mutation, biology.protein, RNA Polymerase II, Somatic Hypermutation, Immunoglobulin, Chromatin immunoprecipitation, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f049bc5a8ee3e29ffcfaadef56d0c2Test
https://pubmed.ncbi.nlm.nih.gov/23087403Test

المؤلفون: Vera, Batrak, Artem, Blagodatski, Jean-Marie, Buerstedde

المصدر: Methods in molecular biology (Clifton, N.J.). 745

مصطلحات موضوعية: Cell Line, Tumor, Mutation, Animals, Immunoglobulins, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, Flow Cytometry, Chickens, Polymerase Chain Reaction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::f8674eaddf727767614b6b5d9912a425Test
https://pubmed.ncbi.nlm.nih.gov/21660702Test

المؤلفون: Koji Kikuchi, Shunichi Takeda, Alihossein Saberi, Hiroshi Arakawa, Julian E. Sale, Makoto Nakahara, Jean-Marie Buerstedde, Ken Ichi Yamamoto, Eiichiro Sonoda

المصدر: Molecular and cellular biology. 28(19)

مصطلحات موضوعية: Immunoglobulin gene, Mutant, RAD51, Gene Conversion, Cell Cycle Proteins, Cell Line, Bursa of Fabricius, Cytidine Deaminase, Proliferating Cell Nuclear Antigen, Animals, Gene conversion, Molecular Biology, Recombination, Genetic, B-Lymphocytes, DNA clamp, biology, Genes, Immunoglobulin, Point mutation, Ubiquitination, Cell Biology, DNA, Articles, Molecular biology, Mutation, biology.protein, Antibody, Homologous recombination, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8626caa5c4af98367ddadedcb1db0c0aTest
https://pubmed.ncbi.nlm.nih.gov/18662998Test

المؤلفون: Artem Blagodatski, Jean-Marie Buerstedde, Sabine Schmidl, Hiroshi Arakawa, Ulrike Schoetz, Vera Batrak, Randolph B. Caldwell

المصدر: PLoS Genetics
PLoS Genetics, Vol 5, Iss 1, p e1000332 (2009)
PLoS Genet. 5:e1000332 (2009)

مصطلحات موضوعية: Cancer Research, lcsh:QH426-470, Green Fluorescent Proteins, Somatic hypermutation, Locus (genetics), Regulatory Sequences, Nucleic Acid, Transfection, Transcription (biology), Genes, Reporter, Cytidine Deaminase, Genetics, Activation-induced (cytidine) deaminase, Animals, Insertion, Gene, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, AID, B cell, DT40, enhancer, gene conversion, immunoglobulin, somatic hypermutation, transcription, B-Lymphocytes, biology, Activator (genetics), Chromosome Mapping, Genetic Variation, Cytidine deaminase, Sequence Analysis, DNA, Cell Biology, Flow Cytometry, lcsh:Genetics, Gene Expression Regulation, Mutation, biology.protein, Genetics and Genomics/Genetics of the Immune System, Genes, Immunoglobulin Light Chain, Somatic Hypermutation, Immunoglobulin, Immunology/Genetics of the Immune System, Chickens, Gene Deletion, Research Article, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9303381e5327b68fc6465265d13502Test
https://pubmed.ncbi.nlm.nih.gov/19132090Test