المؤلفون: Pavithran Keechilat, Chethampadi Gopi Mohan, Lalitha Biswas, Anu R. Melge, Pooja S. Panicker

المصدر: Chemical Biology & Drug Design. 90:629-636

مصطلحات موضوعية: 0301 basic medicine, Databases, Pharmaceutical, Quantitative Structure-Activity Relationship, Antineoplastic Agents, Computational biology, Pharmacology, Hydroxamic Acids, Biochemistry, Small Molecule Libraries, Erlotinib Hydrochloride, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, Drug Discovery, medicine, Humans, Epidermal growth factor receptor, Protein Kinase Inhibitors, EGFR inhibitors, Virtual screening, biology, Drug discovery, Chemistry, Organic Chemistry, ErbB Receptors, Molecular Docking Simulation, 030104 developmental biology, Drug Design, 030220 oncology & carcinogenesis, Mutation, Quinazolines, biology.protein, Computer-Aided Design, Molecular Medicine, Erlotinib, Pharmacophore, Decoy, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787d72413eccea881eca90c0b57bf918Test
https://doi.org/10.1111/cbdd.12977Test

المؤلفون: Erika Martinelli, Elena Vigliar, Floriana Morgillo, Fortunato Ciardiello, Giancarlo Troncone, Teresa Troiani, Carminia Maria Della Corte, Umberto Malapelle, Vincenza Ciaramella, Francesco Pepe, Valentina Belli

المساهمون: Della Corte, Cm, Malapelle, U, Vigliar, E, Pepe, F, Troncone, G, Ciaramella, V, Troiani, Teresa, Martinelli, Erika, Belli, V, Ciardiello, Fortunato, Morgillo, Floriana, Della Corte, Carminia Maria, Malapelle, Umberto, Vigliar, Elena, Pepe, Francesco, Troncone, Giancarlo, Ciaramella, Vincenza, Belli, Valentina

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Afatinib, Cetuximab, Pharmacology, Mice, T790M, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Medicine, Osimertinib, Epidermal growth factor receptor, EGFR inhibitors, Mice, Inbred BALB C, biology, EMT, Gefitinib, cell signalling, ErbB Receptors, EGFR inhibitor, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Female, Erlotinib, Research Paper, Signal Transduction, medicine.drug, hedgehog, Mice, Nude, Antineoplastic Agents, Drug Administration Schedule, Erlotinib Hydrochloride, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Hedgehog Proteins, Protein Kinase Inhibitors, Cell Proliferation, business.industry, Xenograft Model Antitumor Assays, respiratory tract diseases, lung cancer, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Quinazolines, Cancer research, biology.protein, EGFR Activating Mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9f216c256203a3c756669673f4b7bdTest
https://doi.org/10.18632/oncotarget.15479Test

المؤلفون: Ludmila Elfineh, Ulf Martens, Ida-Maria Sintorn, Shimei Wee, Narendra Padhan, Sathishkumar Baskaran, Linnéa Schmidt, Maria Häggblad, Karin Forsberg-Nilsson, Bengt Westermark, Patrik Johansson, Ingrid Lönnstedt, Michael Andäng, Lydia C. Green, Lene Uhrbom, Sven Nelander, Lena Claesson-Welsh, Bo Lundgren, Damian J. Matuszewski, Cecilia Krona

المصدر: Oncotarget

مصطلحات موضوعية: Male, 0301 basic medicine, Pterostilbene, Cell, Pharmacology, stilbenoids, chemistry.chemical_compound, Antineoplastic Combined Chemotherapy Protocols, Stilbenes, EGFR inhibitors, Aged, 80 and over, drug repurposing, Brain Neoplasms, Cell Cycle, Drug Synergism, Gefitinib, Middle Aged, Cell cycle, Phenotype, medicine.anatomical_structure, Oncology, Gene Knockdown Techniques, Chromosomal region, Female, TXNIP, Research Paper, medicine.drug, DNA Copy Number Variations, MAP Kinase Signaling System, cancer therapeutics, 03 medical and health sciences, Cell Line, Tumor, medicine, glioblastoma initiating cells, Humans, Protein Kinase Inhibitors, Aged, Cell Proliferation, Cell growth, business.industry, Gene Expression Profiling, glioblastoma, Antineoplastic Agents, Phytogenic, 030104 developmental biology, chemistry, Mutation, Quinazolines, Transcriptome, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a090c37376c7b084e8c6c8b00ddb8f5Test
https://doi.org/10.18632/oncotarget.12298Test

المؤلفون: Tomonori Haruma, Kaoru Funabashi, Koichi Goto, Kazutaka Miyadera, Mikiko Shibuya, Ryoto Fujita, Daniel B. Costa, Rumi Fujioka, Shinichi Hasako, Toshiharu Komori, Yumi Hakozaki, Miki Terasaka, Naomi Abe, Akihiro Hashimoto, Hibiki Udagawa, Susumu Kobayashi, Akihiro Ohashi, Hiroyuki Yasuda

المصدر: Mol Cancer Res

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, Afatinib, Antineoplastic Agents, medicine.disease_cause, Article, 03 medical and health sciences, Exon, Erlotinib Hydrochloride, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Benzene Derivatives, Humans, Osimertinib, Lung cancer, Molecular Biology, Protein Kinase Inhibitors, EGFR inhibitors, Mutation, Acrylamides, Aniline Compounds, business.industry, Indolizines, Poziotinib, Exons, medicine.disease, respiratory tract diseases, ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Quinazolines, Erlotinib, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daf5b52fb3871eea522a9ccb0bce480Test
https://pubmed.ncbi.nlm.nih.gov/31467113Test

المؤلفون: Ajay Manaithiya, Tauquir Alam, Ozair Alam, Perwaiz Alam, Vrinda Sharma, Parth Bhatia, Kahksha, Mohd. Imran

المصدر: European Journal of Medicinal Chemistry. 204:112640

مصطلحات موضوعية: 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Breast cancer, Pancreatic cancer, Drug Discovery, medicine, Quinazoline, Humans, Osimertinib, Lung cancer, Protein Kinase Inhibitors, 030304 developmental biology, EGFR inhibitors, Pharmacology, 0303 health sciences, 010405 organic chemistry, Kinase, Organic Chemistry, General Medicine, medicine.disease, 0104 chemical sciences, ErbB Receptors, Molecular Docking Simulation, chemistry, Drug Resistance, Neoplasm, Mutation, Quinazolines, Cancer research, Over expression

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b1b9e4015b43b9562117c80693ca23Test
https://doi.org/10.1016/j.ejmech.2020.112640Test

المؤلفون: Cheng-Chu Zeng, Leifu Yang, Xuemei Qin, Peng Liu, Zhipeng Li, Liming Hu, Zhiyong Pan

المصدر: Bioorganic & Medicinal Chemistry. 24:2871-2881

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Inhibitory Concentration 50, 03 medical and health sciences, T790M, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, Quinazoline, Humans, Potency, Epidermal growth factor receptor, Molecular Biology, IC50, Cell Proliferation, EGFR inhibitors, Molecular Structure, biology, Kinase, Organic Chemistry, respiratory tract diseases, ErbB Receptors, 030104 developmental biology, chemistry, A549 Cells, Docking (molecular), 030220 oncology & carcinogenesis, Mutation, Quinazolines, biology.protein, Molecular Medicine, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a5b76486e3ee1d0f58aa1777cfc6f1Test
https://doi.org/10.1016/j.bmc.2016.01.003Test

المؤلفون: Mark Yang, Jia-Lin Yang, David Goldstein, Philip J. Crowe, Kerryn Garrett, Xiaochun Wang, Nikolajs Zeps

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, Pathology, sarcoma, medicine.medical_treatment, Drug resistance, Targeted therapy, STAT3, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Epidermal growth factor receptor, EGFR inhibitors, Mice, Inbred BALB C, biology, Soft tissue sarcoma, Benzenesulfonates, Drug Synergism, Gefitinib, targeted therapy, ErbB Receptors, Treatment Outcome, 030220 oncology & carcinogenesis, Sarcoma, medicine.drug, Research Paper, Signal Transduction, STAT3 Transcription Factor, medicine.medical_specialty, EGFR, Blotting, Western, Mice, Nude, resistance, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Protein Kinase Inhibitors, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Aminosalicylic Acids, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, biology.protein, Quinazolines, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4882c5d18cfb9c26e30e79c7f194ba96Test
http://europepmc.org/articles/PMC5008301Test

المؤلفون: David F, Heigener, Christian, Schumann, Martin, Sebastian, Parvis, Sadjadian, Ingo, Stehle, Angela, Märten, Anne, Lüers, Frank, Griesinger, Matthias, Scheffler, I, Zander

المصدر: The Oncologist. 20:1167-1174

مصطلحات موضوعية: Adult, Compassionate Use Trials, Male, Oncology, Cancer Research, medicine.medical_specialty, Pathology, Lung Neoplasms, Afatinib, medicine.medical_treatment, Antineoplastic Agents, Exon, T790M, Carcinoma, Non-Small-Cell Lung, Internal medicine, medicine, Humans, Treatment Failure, Epidermal growth factor receptor, Lung cancer, Protein Kinase Inhibitors, Aged, EGFR inhibitors, Aged, 80 and over, Chemotherapy, biology, business.industry, Point mutation, Lung Cancer, Middle Aged, medicine.disease, respiratory tract diseases, ErbB Receptors, Mutation, Quinazolines, biology.protein, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8afc83c1cb04ba5a5c3ba0e93fb1d0cTest
https://doi.org/10.1634/theoncologist.2015-0073Test

المؤلفون: Amir Faisal, Kwai-Ming J. Cheung, Julian Blagg, Grace Mak, Amy Wood, Swen Hoelder, Paul Workman, Craig McAndrew, Kathy Boxall, Mark D. Gurden, Rob L. M. van Montfort, Spiros Linardopoulos, Jessica Schmitt, Sébastien Naud, Rosemary Burke, Isaac M. Westwood

المصدر: Cancer Research. 75:3340-3354

مصطلحات موضوعية: Models, Molecular, Cancer Research, Cell Survival, medicine.medical_treatment, Cell Cycle Proteins, Drug resistance, Protein Serine-Threonine Kinases, Pharmacology, Biology, medicine.disease_cause, Heterocyclic Compounds, 2-Ring, Targeted therapy, Gefitinib, Cell Line, Tumor, Neoplasms, medicine, Humans, Point Mutation, Protein Kinase Inhibitors, EGFR inhibitors, Mutation, Aniline Compounds, Dose-Response Relationship, Drug, Molecular Structure, Point mutation, Cancer, Protein-Tyrosine Kinases, HCT116 Cells, medicine.disease, Protein Structure, Tertiary, ErbB Receptors, HEK293 Cells, Oncology, Drug Resistance, Neoplasm, Cancer cell, Quinazolines, Cancer research, Pyrazoles, Protein Binding, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddf1bc7cf1e14d08b8022796a1b8910Test
https://doi.org/10.1158/0008-5472.can-14-3272Test

المؤلفون: Hong Yan, Victor Ho-Fun Lee, Bin Zou

المصدر: BMC Bioinformatics
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Multilinear principal component analysis, Drug resistance, Biology, lcsh:Computer applications to medicine. Medical informatics, Epidermal growth factor receptor mutation, Biochemistry, 03 medical and health sciences, Exon, Erlotinib Hydrochloride, 0302 clinical medicine, Gefitinib, Structural Biology, Carcinoma, Non-Small-Cell Lung, medicine, Humans, Computer Simulation, Molecular Biology, lcsh:QH301-705.5, neoplasms, Protein Kinase Inhibitors, EGFR inhibitors, Principal Component Analysis, Drug discovery, Molecular dynamics simulations, Applied Mathematics, Point mutation, Exons, Computer Science Applications, respiratory tract diseases, ErbB Receptors, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Mutation, Cancer research, Quinazolines, lcsh:R858-859.7, Interaction fingerprints, Erlotinib, medicine.drug, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28dd2f1611fc82d14455047cc2dc3b3Test
http://europepmc.org/articles/PMC5842518Test