دورية أكاديمية
Association between the Mediterranean Diet and Metabolic Syndrome with Serum Levels of miRNA in Morbid Obesity.
| العنوان: | Association between the Mediterranean Diet and Metabolic Syndrome with Serum Levels of miRNA in Morbid Obesity. |
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| المؤلفون: | Fontalba-Romero, María I, Lopez-Enriquez, Soledad, Lago-Sampedro, Ana, García-Escobar, Eva, Pastori, Ricardo L, Domínguez-Bendala, Juan, Álvarez-Cubela, Silvia, Valdes, Sergio, Rojo, Gemma, Garcia-Fuentes, Eduardo, Labajos-Manzanares, María T, García-Serrano, Sara |
| سنة النشر: | 2021 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | Mediterranean diet, metabolic syndrome, miRNA, morbid obesity, type 2 diabetes mellitus, Cardiometabolic Risk Factors, Diabetes Mellitus, Type 2, Diet Surveys, Diet, Mediterranean, Eating, Female, Humans, Incidence, Male, MicroRNAs, Middle Aged, Obesity, Morbid, Patient Compliance |
| الوصف: | The Mediterranean diet (MD) could be involved in the regulation of different miRNAs related to metabolic syndrome (MS). We analyzed the serum level of mir-let7a-5p, mir-21, mir-590, mir-107 and mir-192 in patients with morbid obesity and its association with the MD and MS. There is an association between the adherence to MD and higher serum levels of mir-590. Mir-590 was lower in those patients who consumed >2 commercial pastries/week. Mir-let7a was lower in those who consumed ≥1 sweetened drinks, in those who consumed ≥3 pieces of fruit/day and in those who consumed less red than white meat. A lower mir-590 and mir-let7a, and a higher mir-192 level, were found in patients who met the high-density lipoprotein cholesterol (HDL) criterion of MS. A higher mir-192 was found in those patients who met the triglyceride criterion of MS and in those with type 2 diabetes (T2DM). There is an association between specific serum levels of miRNAs and the amount and kind of food intake related to MD. Mir-590 was positively associated with a healthy metabolic profile and type of diet, while mir-192 was positively associated with a worse metabolic profile. These associations could be suggestive of a possible modulation of these miRNAs by food. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| العلاقة: | http://hdl.handle.net/10668/17155Test; PMC7911421; https://www.mdpi.com/2072-6643/13/2/436/pdf?version=1612533860Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911421/pdfTest |
| DOI: | 10.3390/nu13020436 |
| الإتاحة: | https://doi.org/10.3390/nu13020436Test http://hdl.handle.net/10668/17155Test https://www.mdpi.com/2072-6643/13/2/436/pdf?version=1612533860Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911421/pdfTest |
| حقوق: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0Test/ ; open access |
| رقم الانضمام: | edsbas.5D678C76 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20726643 |
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| DOI: | 10.3390/nu13020436 |