المؤلفون: Tana Tandarić, Alja Prah, Jernej Stare, Janez Mavri, Robert Vianello

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 17; Pages: 6151

مصطلحات موضوعية: irreversible inhibition, monoamine oxidase, hydride transfer, antiparkinsonian drugs, neurodegeneration, flavoenzymes

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms21176151Test

الإتاحة: https://doi.org/10.3390/ijms21176151Test

المؤلفون: Rona R. Ramsay, Alen Albreht

المصدر: Chemistry, Vol 3, Iss 69, Pp 959-978 (2021)

مصطلحات موضوعية: kinetic mechanism, cysteine modification, oxidation, Monoamine oxidase, Chemistry, protein flexibility, General Medicine, Computational biology, reversible/irreversible inhibition, Monoamine neurotransmitter, chemical mechanism, Clinical information, QD1-999

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0dbd1066af8717a50c175aedacf37cTest
https://doi.org/10.3390/chemistry3030069Test

المؤلفون: Rona R. Ramsay, Matteo Pappalardo, Livia Basile, Maria Chiara Saija, Stefanie Hagenow, Sharon D. Bryant, Antonin Maniquet, Alen Albreht, Salvatore Guccione

المساهمون: University of St Andrews. School of Biology

المصدر: Molecules, Vol 25, Iss 5908, p 5908 (2020)
Molecules
Volume 25
Issue 24

مصطلحات موضوعية: computational modeling, Time Factors, QH301 Biology, Molecular Conformation, Pharmaceutical Science, Analytical Chemistry, Substrate Specificity, spectrum, chemistry.chemical_compound, 0302 clinical medicine, enzyme kinetics, Drug Discovery, Neurotransmitter metabolism, QD, 0303 health sciences, biology, adduct, Molecular Structure, Irreversible inhibition, Computational modeling, Molecular Docking Simulation, Chemistry (miscellaneous), Covalent bond, Molecular Medicine, Adduct, Oxidation-Reduction, Protein Binding, RM, Monoamine Oxidase Inhibitors, Monoamine oxidase, Stereochemistry, Imine, Flavin group, Molecular Dynamics Simulation, Cofactor, Article, lcsh:QD241-441, 03 medical and health sciences, QH301, Inhibitory Concentration 50, Structure-Activity Relationship, SDG 3 - Good Health and Well-being, lcsh:Organic chemistry, Spectrum, Humans, FAD, irreversible inhibition, enzyme kinetics, computational modeling, pharmacophore, spectrum, adduct, Physical and Theoretical Chemistry, Binding site, Monoamine Oxidase, 030304 developmental biology, irreversible inhibition, Binding Sites, Pharmacophore, Dose-Response Relationship, Drug, pharmacophore, FAD, Organic Chemistry, Enzyme kinetics, DAS, QD Chemistry, RM Therapeutics. Pharmacology, Enzyme Activation, Kinetics, chemistry, biology.protein, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcd8edd8493c4c963ee67729f94cea6Test
https://www.mdpi.com/1420-3049/25/24/5908Test

المؤلفون: Jernej Stare, Tana Tandarić, Robert Vianello, Janez Mavri, Alja Prah

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 6151, p 6151 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 17
International journal of molecular sciences

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, Pharmacy, lcsh:Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Catalytic Domain, lcsh:QH301-705.5, Spectroscopy, Molecular Structure, Chemistry, Selegiline, neurodegeneration, General Medicine, Rate-determining step, 3. Good health, Computer Science Applications, Indans, Flavin-Adenine Dinucleotide, Monoamine oxidase B, medicine.drug, Monoamine Oxidase Inhibitors, Monoamine oxidase, antiparkinsonian drugs, Flavin group, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, hydride transfer, medicine, Humans, Computer Simulation, Physical and Theoretical Chemistry, Molecular Biology, Monoamine Oxidase, irreversible inhibition, Rasagiline, Organic Chemistry, monoamine oxidase, flavoenzymes, Rational design, Combinatorial chemistry, 030104 developmental biology, Monoamine neurotransmitter, lcsh:Biology (General), lcsh:QD1-999, Energy Transfer, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd56360eaa73959eaca9e32f5be05a72Test
https://www.bib.irb.hr/1076290Test

المؤلفون: Di Pietro, Ornella, Alencar, Nelson, Esteban, Gerard, Viayna, Elisabet, Szałaj, Natalia, Vázquez, Javier, Juárez-Jiménez, Jordi, Sola, Irene, Pérez, Belén, Solé Piñol, Montserrat, Unzeta López, Mercedes, Muñoz-Torrero López-Ibarra, Diego, Luque Garriga, F. Xavier, Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular

المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

مصطلحات موضوعية: 0301 basic medicine, Monoamine Oxidase Inhibitors, Molecular model, Stereochemistry, Clinical Biochemistry, Triazole, Pharmaceutical Science, 01 natural sciences, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, Monoamine oxidase B, Monoamine Oxidase, Molecular Biology, Alkyl, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Irreversible inhibition, Alzheimer's disease, Cycloaddition, 0104 chemical sciences, Molecular Docking Simulation, 030104 developmental biology, Pargyline, chemistry, Click-chemistry, Drug Design, Click chemistry, Molecular Medicine, Selectivity

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df53678fd7026e019de1edc4e4dabc4Test
https://doi.org/10.1016/j.bmc.2016.06.045Test

المؤلفون: Robert Vianello, Tana Tandarić

المصدر: ACS Chemical Neuroscience

مصطلحات موضوعية: Monoamine Oxidase Inhibitors, Physiology, Stereochemistry, Monoamine oxidase, Cognitive Neuroscience, Molecular Dynamics Simulation, Biochemistry, Antiparkinson Agents, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Irreversible inhibition, monoamine oxidase, hydride transfer, antiparkinsonian drugs, neurodegeneration, flavoenzymes, Selegiline, medicine, Humans, Reactivity (chemistry), Monoamine Oxidase, 030304 developmental biology, Rasagiline, Flavin adenine dinucleotide, 0303 health sciences, biology, Active site, Cell Biology, General Medicine, Chemistry, Monoamine neurotransmitter, chemistry, Indans, biology.protein, Monoamine oxidase B, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d4ddfdc0c171ee81b5060bc0af3be3Test
https://www.bib.irb.hr/1015602Test

المؤلفون: Matic Pavlin, Matej Repič, Robert Vianello, Janez Mavri

المصدر: Journal of Neural Transmission. 120:875-882

مصطلحات موضوعية: Clorgyline, Monoamine Oxidase Inhibitors, Monoamine oxidase, medicine.drug_class, Stereochemistry, Flavin group, Computers, Molecular, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, Moiety, Monoamine Oxidase, Biological Psychiatry, 030304 developmental biology, Rasagiline, 0303 health sciences, Monoamine oxidase inhibitor, Selegiline, acetylenic inhibitors, antidepressant target, flavoenzymes, irreversible inhibition, monoamine oxidase inhibitors, Psychiatry and Mental health, Models, Chemical, Neurology, chemistry, Electrophile, Neurology (clinical), 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9930aa4bf4d507fcae00fbb37ddc8fTest
https://doi.org/10.1007/s00702-013-1016-yTest